| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the etilefrine-4590 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 |
| BCL2A1 | BCL2-related protein A1 |
| BMP2 | bone morphogenetic protein 2 |
| C5 | complement component 5 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CD24 | CD24 molecule |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CLDN8 | claudin 8 |
| CLEC11A | C-type lectin domain family 11, member A |
| CREM | cAMP responsive element modulator |
| CTH | cystathionine gamma-lyase |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| DFNB31 | deafness, autosomal recessive 31 |
| DMBT1 | deleted in malignant brain tumors 1 |
| DNASE1L3 | deoxyribonuclease I-like 3 |
| DOK5 | docking protein 5 |
| DUSP1 | dual specificity phosphatase 1 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| EPAS1 | endothelial PAS domain protein 1 |
| ETV1 | ets variant 1 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FLJ42627 | uncharacterized LOC645644 |
| GK | glycerol kinase |
| GK3P | glycerol kinase 3 pseudogene |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A |
| HBEGF | heparin-binding EGF-like growth factor |
| IGL | immunoglobulin lambda locus |
| IL11 | interleukin 11 |
| IL1R2 | interleukin 1 receptor, type II |
| IL33 | interleukin 33 |
| IL33R | interleukin 33 receptor |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| JAK2 | Janus kinase 2 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| KIAA1654 | KIAA1654 protein |
| KLHL28 | kelch-like family member 28 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| KRT17 | keratin 17, type I |
| LIG3 | ligase III, DNA, ATP-dependent |
| LRRC37A4P | leucine rich repeat containing 37, member A4, pseudogene |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MAP7 | microtubule-associated protein 7 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OSBP2 | oxysterol binding protein 2 |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| PALM | paralemmin |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| PDS5A | PDS5 cohesin associated factor A |
| PHF14 | PHD finger protein 14 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) |
| PRR5 | proline rich 5 (renal) |
| PTGES | prostaglandin E synthase |
| PTGFR | prostaglandin F receptor (FP) |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTHLH | parathyroid hormone-like hormone |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
| RBM34 | RNA binding motif protein 34 |
| RGS12 | regulator of G-protein signaling 12 |
| RNGTT | RNA guanylyltransferase and 5'-phosphatase |
| S100P | S100 calcium binding protein P |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SCEL | sciellin |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
| SERPIND1 | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 |
| SIRT4 | sirtuin 4 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 |
| SMOX | spermine oxidase |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| STAT2 | signal transducer and activator of transcription 2, 113kDa |
| STC1 | stanniocalcin 1 |
| TBC1D30 | TBC1 domain family, member 30 |
| TBL1X | transducin (beta)-like 1X-linked |
| TGFB2 | transforming growth factor, beta 2 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TNFSF15 | tumor necrosis factor (ligand) superfamily, member 15 |
| TRIM29 | tripartite motif containing 29 |
| TTC38 | tetratricopeptide repeat domain 38 |
| TTC39A | tetratricopeptide repeat domain 39A |
| ZNF219 | zinc finger protein 219 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| ADRB2 | adrenoceptor beta 2, surface |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| BEND5 | BEN domain containing 5 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CASZ1 | castor zinc finger 1 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CDKN2AIP | CDKN2A interacting protein |
| CDON | cell adhesion associated, oncogene regulated |
| CINP | cyclin-dependent kinase 2 interacting protein |
| CLCA1 | chloride channel accessory 1 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| COPG2IT1 | COPG2 imprinted transcript 1 (non-protein coding) |
| CPNE7 | copine VII |
| CSF1R | colony stimulating factor 1 receptor |
| CTGF | connective tissue growth factor |
| DDX51 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FJX1 | four jointed box 1 (Drosophila) |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| G0S2 | G0/G1 switch 2 |
| GAS8 | growth arrest-specific 8 |
| GBX2 | gastrulation brain homeobox 2 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| GPATCH2 | G patch domain containing 2 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GRAMD1C | GRAM domain containing 1C |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HDAC9 | histone deacetylase 9 |
| HIST1H2BO | histone cluster 1, H2bo |
| HIST1H4E | histone cluster 1, H4e |
| HOXB9 | homeobox B9 |
| INHBB | inhibin, beta B |
| KIAA0513 | KIAA0513 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LMCD1 | LIM and cysteine-rich domains 1 |
| MEGF8 | multiple EGF-like-domains 8 |
| MFSD6 | major facilitator superfamily domain containing 6 |
| MGP | matrix Gla protein |
| MYL5 | myosin, light chain 5, regulatory |
| MYO1F | myosin IF |
| NPY1R | neuropeptide Y receptor Y1 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| OLFML2A | olfactomedin-like 2A |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PDE12 | phosphodiesterase 12 |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 |
| PLA2G15 | phospholipase A2, group XV |
| POLH | polymerase (DNA directed), eta |
| PROX1 | prospero homeobox 1 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| PTX3 | pentraxin 3, long |
| PXDC1 | PX domain containing 1 |
| RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 |
| RGS17 | regulator of G-protein signaling 17 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RUNDC3B | RUN domain containing 3B |
| SCG5 | secretogranin V |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SOBP | sine oculis binding protein homolog (Drosophila) |
| SPEG | SPEG complex locus |
| SYNPO | synaptopodin |
| SYT17 | synaptotagmin XVII |
| TEAD3 | TEA domain family member 3 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TMEM159 | transmembrane protein 159 |
| TOM1 | target of myb1 (chicken) |
| TSC22D4 | TSC22 domain family, member 4 |
| TSPAN2 | tetraspanin 2 |
| TUBA3C | tubulin, alpha 3c |
| TUBG2 | tubulin, gamma 2 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| UBTD1 | ubiquitin domain containing 1 |
| WNT7A | wingless-type MMTV integration site family, member 7A |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF253 | zinc finger protein 253 |
| ZNF343 | zinc finger protein 343 |
| ZNF385D | zinc finger protein 385D |
| ZNF671 | zinc finger protein 671 |