| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the etilefrine-7350 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM22 | ADAM metallopeptidase domain 22 |
| AGFG1 | ArfGAP with FG repeats 1 |
| AHI1 | Abelson helper integration site 1 |
| AIM2 | absent in melanoma 2 |
| AK1 | adenylate kinase 1 |
| ALS2CL | ALS2 C-terminal like |
| ANPEP | alanyl (membrane) aminopeptidase |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| ATN1 | atrophin 1 |
| BCL3 | B-cell CLL/lymphoma 3 |
| BMP1 | bone morphogenetic protein 1 |
| CA9 | carbonic anhydrase IX |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CD83 | CD83 molecule |
| CHKB | choline kinase beta |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CLEC11A | C-type lectin domain family 11, member A |
| COL6A1 | collagen, type VI, alpha 1 |
| CSF1R | colony stimulating factor 1 receptor |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| ESRRA | estrogen-related receptor alpha |
| FAM120C | family with sequence similarity 120C |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FH | fumarate hydratase |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GPC1 | glypican 1 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GSTP1 | glutathione S-transferase pi 1 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HBEGF | heparin-binding EGF-like growth factor |
| HFE | hemochromatosis |
| HIST1H4E | histone cluster 1, H4e |
| HLA-G | major histocompatibility complex, class I, G |
| HOXC8 | homeobox C8 |
| IFT38 | intraflagellar transport 38 |
| INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
| ITGB4 | integrin, beta 4 |
| LHX6 | LIM homeobox 6 |
| LILRA1 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 |
| LILRB1 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 |
| LMF1 | lipase maturation factor 1 |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MED16 | mediator complex subunit 16 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NF2 | neurofibromin 2 (merlin) |
| NOS1 | nitric oxide synthase 1 (neuronal) |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NUP214 | nucleoporin 214kDa |
| PAOX | polyamine oxidase (exo-N4-amino) |
| PCDHA9 | protocadherin alpha 9 |
| PCGF3 | polycomb group ring finger 3 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDK2 | pyruvate dehydrogenase kinase, isozyme 2 |
| PER3 | period circadian clock 3 |
| PGLYRP4 | peptidoglycan recognition protein 4 |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| POU5F1B | POU class 5 homeobox 1B |
| PRDX2 | peroxiredoxin 2 |
| PRPH | peripherin |
| PTPRCAP | protein tyrosine phosphatase, receptor type, C-associated protein |
| PXN | paxillin |
| RASAL2 | RAS protein activator like 2 |
| RCN3 | reticulocalbin 3, EF-hand calcium binding domain |
| S100A8 | S100 calcium binding protein A8 |
| S100A9 | S100 calcium binding protein A9 |
| SIX2 | SIX homeobox 2 |
| SNRK | SNF related kinase |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SSPN | sarcospan |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| STK17A | serine/threonine kinase 17a |
| STMN1 | stathmin 1 |
| STON1 | stonin 1 |
| SUGP1 | SURP and G patch domain containing 1 |
| TLR5 | toll-like receptor 5 |
| TNK1 | tyrosine kinase, non-receptor, 1 |
| TOP3A | topoisomerase (DNA) III alpha |
| TOP3B | topoisomerase (DNA) III beta |
| TPP1 | tripeptidyl peptidase I |
| TROVE2 | TROVE domain family, member 2 |
| TTBK2 | tau tubulin kinase 2 |
| TTC33 | tetratricopeptide repeat domain 33 |
| UBXN6 | UBX domain protein 6 |
| USP20 | ubiquitin specific peptidase 20 |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| WNK1 | WNK lysine deficient protein kinase 1 |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF783 | zinc finger family member 783 |
| ZNRD1-AS1 | ZNRD1 antisense RNA 1 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| AFAP1 | actin filament associated protein 1 |
| AMDHD2 | amidohydrolase domain containing 2 |
| AMPD2 | adenosine monophosphate deaminase 2 |
| ANKEF1 | ankyrin repeat and EF-hand domain containing 1 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ATAD3A | ATPase family, AAA domain containing 3A |
| ATXN2 | ataxin 2 |
| AXIN1 | axin 1 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BCAS1 | breast carcinoma amplified sequence 1 |
| BTBD2 | BTB (POZ) domain containing 2 |
| C5 | complement component 5 |
| CAPN15 | calpain 15 |
| CDK5 | cyclin-dependent kinase 5 |
| CEP97 | centrosomal protein 97kDa |
| CSNK1E | casein kinase 1, epsilon |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DNALI1 | dynein, axonemal, light intermediate chain 1 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| DYSF | dysferlin |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) |
| EPHA2 | EPH receptor A2 |
| ERCC4 | excision repair cross-complementation group 4 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FCHO1 | FCH domain only 1 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FLJ11710 | uncharacterized protein FLJ11710 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| GPATCH2L | G patch domain containing 2-like |
| GPR27 | G protein-coupled receptor 27 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HOXC10 | homeobox C10 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IL17RA | interleukin 17 receptor A |
| IL4R | interleukin 4 receptor |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KDM5C | lysine (K)-specific demethylase 5C |
| KRT24 | keratin 24, type I |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LRRC20 | leucine rich repeat containing 20 |
| LRRC61 | leucine rich repeat containing 61 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MAPK8 | mitogen-activated protein kinase 8 |
| MATK | megakaryocyte-associated tyrosine kinase |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MCC | mutated in colorectal cancers |
| MED9 | mediator complex subunit 9 |
| MITF | microphthalmia-associated transcription factor |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MTERF4 | mitochondrial transcription termination factor 4 |
| NACA2 | nascent polypeptide-associated complex alpha subunit 2 |
| NCAM2 | neural cell adhesion molecule 2 |
| NEK11 | NIMA-related kinase 11 |
| NFRKB | nuclear factor related to kappaB binding protein |
| NKX3-2 | NK3 homeobox 2 |
| NPY1R | neuropeptide Y receptor Y1 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PCDHB3 | protocadherin beta 3 |
| PGP | phosphoglycolate phosphatase |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RANBP17 | RAN binding protein 17 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RNF31 | ring finger protein 31 |
| RPAP1 | RNA polymerase II associated protein 1 |
| SETD1A | SET domain containing 1A |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SH2D4A | SH2 domain containing 4A |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| STK16 | serine/threonine kinase 16 |
| TBC1D17 | TBC1 domain family, member 17 |
| TCTN1 | tectonic family member 1 |
| TMC5 | transmembrane channel-like 5 |
| TMPRSS3 | transmembrane protease, serine 3 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| VASH1 | vasohibin 1 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WDR62 | WD repeat domain 62 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZMYM3 | zinc finger, MYM-type 3 |
| ZNF16 | zinc finger protein 16 |
| ZNF428 | zinc finger protein 428 |
| ZNF506 | zinc finger protein 506 |
| ZNF747 | zinc finger protein 747 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |
