etiocholanolone-2204 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the etiocholanolone-2204 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ACVR1B activin A receptor, type IB
ACVRL1 activin A receptor type II-like 1
ATHL1 ATH1, acid trehalase-like 1 (yeast)
ATP10A ATPase, class V, type 10A
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
B9D1 B9 protein domain 1
BCAS1 breast carcinoma amplified sequence 1
BIN1 bridging integrator 1
BMP7 bone morphogenetic protein 7
BTN3A1 butyrophilin, subfamily 3, member A1
C18ORF25 chromosome 18 open reading frame 25
C5 complement component 5
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD84 CD84 molecule
CEACAM21 carcinoembryonic antigen-related cell adhesion molecule 21
CEACAM3 carcinoembryonic antigen-related cell adhesion molecule 3
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CNPPD1 cyclin Pas1/PHO80 domain containing 1
COLEC10 collectin sub-family member 10 (C-type lectin)
COPZ2 coatomer protein complex, subunit zeta 2
CTIF CBP80/20-dependent translation initiation factor
DCAF15 DDB1 and CUL4 associated factor 15
DUSP7 dual specificity phosphatase 7
EDRF1 erythroid differentiation regulatory factor 1
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EHD3 EH-domain containing 3
FAM86C1 family with sequence similarity 86, member C1
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIST1H4E histone cluster 1, H4e
HSF1 heat shock transcription factor 1
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IGLJ3 immunoglobulin lambda joining 3
KLF3 Kruppel-like factor 3 (basic)
KLRAP1 killer cell lectin-like receptor subfamily A pseudogene 1
KRT81 keratin 81, type II
LEF1 lymphoid enhancer-binding factor 1
LMF2 lipase maturation factor 2
MARC1 mitochondrial amidoxime reducing component 1
MBNL3 muscleblind-like splicing regulator 3
MBP myelin basic protein
MEF2C myocyte enhancer factor 2C
MSC musculin
MT1G metallothionein 1G
MUC1 mucin 1, cell surface associated
MYOF myoferlin
NABP1 nucleic acid binding protein 1
NF2 neurofibromin 2 (merlin)
NOL10 nucleolar protein 10
NPEPL1 aminopeptidase-like 1
NPY6R neuropeptide Y receptor Y6 (pseudogene)
OLFML2B olfactomedin-like 2B
PAIP2B poly(A) binding protein interacting protein 2B
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PCSK6 proprotein convertase subtilisin/kexin type 6
PDGFRL platelet-derived growth factor receptor-like
PIAS2 protein inhibitor of activated STAT, 2
PKD2L2 polycystic kidney disease 2-like 2
PLAA phospholipase A2-activating protein
PLD3 phospholipase D family, member 3
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRPF18 pre-mRNA processing factor 18
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RAB40AL RAB40A, member RAS oncogene family-like
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RND1 Rho family GTPase 1
SDS serine dehydratase
SGK2 serum/glucocorticoid regulated kinase 2
SLAMF7 SLAM family member 7
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SMG7 SMG7 nonsense mediated mRNA decay factor
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOGA1 suppressor of glucose, autophagy associated 1
SORBS3 sorbin and SH3 domain containing 3
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SV2B synaptic vesicle glycoprotein 2B
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TEX15 testis expressed 15
TLN2 talin 2
TMEM140 transmembrane protein 140
TMEM63A transmembrane protein 63A
TMOD3 tropomodulin 3 (ubiquitous)
TSC22D2 TSC22 domain family, member 2
TYRO3 TYRO3 protein tyrosine kinase
UBE2I ubiquitin-conjugating enzyme E2I
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
USP46 ubiquitin specific peptidase 46
VEGFB vascular endothelial growth factor B
WRAP53 WD repeat containing, antisense to TP53
XIST X inactive specific transcript (non-protein coding)
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF154 zinc finger protein 154
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ABCF3 ATP-binding cassette, sub-family F (GCN20), member 3
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATG2B autophagy related 2B
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BIK BCL2-interacting killer (apoptosis-inducing)
BPI bactericidal/permeability-increasing protein
C1QTNF3 C1q and tumor necrosis factor related protein 3
C2ORF27A chromosome 2 open reading frame 27A
CAND2 cullin-associated and neddylation-dissociated 2 (putative)
CCDC132 coiled-coil domain containing 132
CCDC69 coiled-coil domain containing 69
CD82 CD82 molecule
CDO1 cysteine dioxygenase type 1
CEP41 centrosomal protein 41kDa
COQ6 coenzyme Q6 monooxygenase
CORT cortistatin
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CPTP ceramide-1-phosphate transfer protein
CRELD1 cysteine-rich with EGF-like domains 1
CXORF56 chromosome X open reading frame 56
EPX eosinophil peroxidase
ERCC2 excision repair cross-complementation group 2
ERN2 endoplasmic reticulum to nucleus signaling 2
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FSTL3 follistatin-like 3 (secreted glycoprotein)
GJA1 gap junction protein, alpha 1, 43kDa
GLCE glucuronic acid epimerase
GPR27 G protein-coupled receptor 27
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HCAR3 hydroxycarboxylic acid receptor 3
HIST1H2AI histone cluster 1, H2ai
HIST1H2AM histone cluster 1, H2am
HIST1H2BI histone cluster 1, H2bi
HYAL2 hyaluronoglucosaminidase 2
IDI2-AS1 IDI2 antisense RNA 1
IFNA14 interferon, alpha 14
IFT81 intraflagellar transport 81
IQCC IQ motif containing C
ITGA10 integrin, alpha 10
ITGB7 integrin, beta 7
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
LIMS2 LIM and senescent cell antigen-like domains 2
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRRC20 leucine rich repeat containing 20
LTBP2 latent transforming growth factor beta binding protein 2
LZTS3 leucine zipper, putative tumor suppressor family member 3
MCPH1 microcephalin 1
MED15 mediator complex subunit 15
MEGF8 multiple EGF-like-domains 8
MICALL2 MICAL-like 2
MST1 macrophage stimulating 1
MTMR12 myotubularin related protein 12
MYBPH myosin binding protein H
NCS1 neuronal calcium sensor 1
NHEJ1 nonhomologous end-joining factor 1
PCDHGB5 protocadherin gamma subfamily B, 5
PFN2 profilin 2
PLCD1 phospholipase C, delta 1
PLP1 proteolipid protein 1
PODNL1 podocan-like 1
PRKCZ protein kinase C, zeta
PTPRS protein tyrosine phosphatase, receptor type, S
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAB17 RAB17, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RAD51B RAD51 paralog B
RFPL3 ret finger protein-like 3
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RNASE3 ribonuclease, RNase A family, 3
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RRAGB Ras-related GTP binding B
SEC14L5 SEC14-like 5 (S. cerevisiae)
SLC12A8 solute carrier family 12, member 8
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
SPATA1 spermatogenesis associated 1
STARD5 StAR-related lipid transfer (START) domain containing 5
TAS2R10 taste receptor, type 2, member 10
TBC1D19 TBC1 domain family, member 19
TGFBR3 transforming growth factor, beta receptor III
TPM3 tropomyosin 3
TRIM25 tripartite motif containing 25
TSC22D4 TSC22 domain family, member 4
TSPYL2 TSPY-like 2
TUBA4B tubulin, alpha 4b
TUBG2 tubulin, gamma 2
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UCN urocortin
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
VSIG10 V-set and immunoglobulin domain containing 10
XDH xanthine dehydrogenase
ZFHX2 zinc finger homeobox 2
ZMAT3 zinc finger, matrin-type 3
ZNF222 zinc finger protein 222
ZNF254 zinc finger protein 254
ZNF668 zinc finger protein 668