etiocholanolone-3639 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the etiocholanolone-3639 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACPP acid phosphatase, prostate
ADAM28 ADAM metallopeptidase domain 28
ADORA1 adenosine A1 receptor
C14ORF79 chromosome 14 open reading frame 79
C19ORF57 chromosome 19 open reading frame 57
C21ORF2 chromosome 21 open reading frame 2
C4BPA complement component 4 binding protein, alpha
CALML3 calmodulin-like 3
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CARD9 caspase recruitment domain family, member 9
CARTPT CART prepropeptide
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
CD22 CD22 molecule
CD80 CD80 molecule
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CLCF1 cardiotrophin-like cytokine factor 1
CNTD2 cyclin N-terminal domain containing 2
CORO7 coronin 7
CPS1 carbamoyl-phosphate synthase 1, mitochondrial
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
ECE1 endothelin converting enzyme 1
EFR3B EFR3 homolog B (S. cerevisiae)
FN1 fibronectin 1
FSHB follicle stimulating hormone, beta polypeptide
FSTL4 follistatin-like 4
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GLIPR1 GLI pathogenesis-related 1
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GPM6A glycoprotein M6A
HABP2 hyaluronan binding protein 2
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HFE hemochromatosis
HOXA9 homeobox A9
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IGLV3-19 immunoglobulin lambda variable 3-19
IL1RAP interleukin 1 receptor accessory protein
INHBA inhibin, beta A
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
KCNK12 potassium channel, two pore domain subfamily K, member 12
KCNMB2 potassium channel subfamily M regulatory beta subunit 2
KIAA1109 KIAA1109
KIF5A kinesin family member 5A
KLK1 kallikrein 1
KLRD1 killer cell lectin-like receptor subfamily D, member 1
KMT2A lysine (K)-specific methyltransferase 2A
LAT2 linker for activation of T cells family, member 2
LOXL2 lysyl oxidase-like 2
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAN1C1 mannosidase, alpha, class 1C, member 1
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MARK4 MAP/microtubule affinity-regulating kinase 4
MST1 macrophage stimulating 1
NCOR2 nuclear receptor corepressor 2
NDN necdin, melanoma antigen (MAGE) family member
NELL2 NEL-like 2 (chicken)
NEUROG1 neurogenin 1
NF1 neurofibromin 1
NMBR neuromedin B receptor
NT5M 5',3'-nucleotidase, mitochondrial
OSBPL10 oxysterol binding protein-like 10
PACS1 phosphofurin acidic cluster sorting protein 1
PGAP3 post-GPI attachment to proteins 3
PHOX2B paired-like homeobox 2b
PITX1 paired-like homeodomain 1
PLAC4 placenta-specific 4
PNMA3 paraneoplastic Ma antigen 3
PRAMEF10 PRAME family member 10
PRDM11 PR domain containing 11
PRDM12 PR domain containing 12
PRPH2 peripherin 2 (retinal degeneration, slow)
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTH1R parathyroid hormone 1 receptor
RAB3B RAB3B, member RAS oncogene family
RGS12 regulator of G-protein signaling 12
RND1 Rho family GTPase 1
S100A8 S100 calcium binding protein A8
SLC19A1 solute carrier family 19 (folate transporter), member 1
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SYNPO synaptopodin
T T, brachyury homolog (mouse)
TAC3 tachykinin 3
TBC1D2 TBC1 domain family, member 2
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TIMP3 TIMP metallopeptidase inhibitor 3
TMOD1 tropomodulin 1
TRABD TraB domain containing
TSNAXIP1 translin-associated factor X interacting protein 1
TTLL4 tubulin tyrosine ligase-like family member 4
UBE3A ubiquitin protein ligase E3A
UMPS uridine monophosphate synthetase
USP2 ubiquitin specific peptidase 2
ZFP64 ZFP64 zinc finger protein
ZNF446 zinc finger protein 446
ZSWIM1 zinc finger, SWIM-type containing 1
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACTG2 actin, gamma 2, smooth muscle, enteric
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADGRE1 adhesion G protein-coupled receptor E1
AGMAT agmatine ureohydrolase (agmatinase)
AHNAK2 AHNAK nucleoprotein 2
AHSP alpha hemoglobin stabilizing protein
AIRE autoimmune regulator
AKAP5 A kinase (PRKA) anchor protein 5
ALPK1 alpha-kinase 1
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BEGAIN brain-enriched guanylate kinase-associated
BMP10 bone morphogenetic protein 10
C5AR1 complement component 5a receptor 1
CAPN5 calpain 5
CCDC71 coiled-coil domain containing 71
CD1A CD1a molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CDK18 cyclin-dependent kinase 18
CFHR4 complement factor H-related 4
CGREF1 cell growth regulator with EF-hand domain 1
CHRM3 cholinergic receptor, muscarinic 3
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPEB3 cytoplasmic polyadenylation element binding protein 3
CRLF1 cytokine receptor-like factor 1
CRY2 cryptochrome circadian clock 2
CUZD1 CUB and zona pellucida-like domains 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DGAT1 diacylglycerol O-acyltransferase 1
DSPP dentin sialophosphoprotein
DVL1 dishevelled segment polarity protein 1
DYSF dysferlin
EGFL7 EGF-like-domain, multiple 7
ERN2 endoplasmic reticulum to nucleus signaling 2
ETV7 ets variant 7
FBXL8 F-box and leucine-rich repeat protein 8
FCN1 ficolin (collagen/fibrinogen domain containing) 1
FKBP10 FK506 binding protein 10, 65 kDa
FLCN folliculin
FRMD1 FERM domain containing 1
GPR176 G protein-coupled receptor 176
GRPR gastrin-releasing peptide receptor
GSTCD glutathione S-transferase, C-terminal domain containing
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HIST1H1D histone cluster 1, H1d
HOXB2 homeobox B2
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
JAM3 junctional adhesion molecule 3
KLF2 Kruppel-like factor 2
KREMEN2 kringle containing transmembrane protein 2
LIME1 Lck interacting transmembrane adaptor 1
MAP2 microtubule-associated protein 2
MATN3 matrilin 3
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MOB3B MOB kinase activator 3B
MRPS18C mitochondrial ribosomal protein S18C
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MYOZ3 myozenin 3
NDE1 nudE neurodevelopment protein 1
NPTX2 neuronal pentraxin II
NPY4R neuropeptide Y receptor Y4
NTF3 neurotrophin 3
NYNRIN NYN domain and retroviral integrase containing
PCDHA5 protocadherin alpha 5
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PLEKHO1 pleckstrin homology domain containing, family O member 1
PRR4 proline rich 4 (lacrimal)
PWAR5 Prader Willi/Angelman region RNA 5
RAD54L2 RAD54-like 2 (S. cerevisiae)
RELN reelin
REM1 RAS (RAD and GEM)-like GTP-binding 1
RFPL1S RFPL1 antisense RNA 1
RNF2 ring finger protein 2
RUFY2 RUN and FYVE domain containing 2
SDC3 syndecan 3
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC16A4 solute carrier family 16, member 4
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
SLIT2 slit homolog 2 (Drosophila)
STAG3L1 stromal antigen 3-like 1 (pseudogene)
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TCTN2 tectonic family member 2
TGFBR1 transforming growth factor, beta receptor 1
TLR2 toll-like receptor 2
TRAIP TRAF interacting protein
TSC22D4 TSC22 domain family, member 4
TYRP1 tyrosinase-related protein 1
VAX2 ventral anterior homeobox 2
VEGFB vascular endothelial growth factor B
VPS9D1 VPS9 domain containing 1
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZIC3 Zic family member 3
ZNF747 zinc finger protein 747
ZSCAN2 zinc finger and SCAN domain containing 2