etiocholanolone-3742 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the etiocholanolone-3742 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ANXA10 annexin A10
ARC activity-regulated cytoskeleton-associated protein
ARMC9 armadillo repeat containing 9
ARNT aryl hydrocarbon receptor nuclear translocator
ART1 ADP-ribosyltransferase 1
ATP9B ATPase, class II, type 9B
BAIAP2 BAI1-associated protein 2
BBC3 BCL2 binding component 3
BCL6 B-cell CLL/lymphoma 6
BMP1 bone morphogenetic protein 1
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C14ORF79 chromosome 14 open reading frame 79
C19ORF57 chromosome 19 open reading frame 57
CA5B carbonic anhydrase VB, mitochondrial
CCDC121 coiled-coil domain containing 121
CCDC177 coiled-coil domain containing 177
CD52 CD52 molecule
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CEL carboxyl ester lipase
CEP250 centrosomal protein 250kDa
CHD9 chromodomain helicase DNA binding protein 9
COPZ2 coatomer protein complex, subunit zeta 2
CROCCP3 ciliary rootlet coiled-coil, rootletin pseudogene 3
CT62 cancer/testis antigen 62
DACH1 dachshund family transcription factor 1
DAPK3 death-associated protein kinase 3
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DNPH1 2'-deoxynucleoside 5'-phosphate N-hydrolase 1
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DPF1 D4, zinc and double PHD fingers family 1
DPY19L1P1 DPY19L1 pseudogene 1
DTNA dystrobrevin, alpha
EFS embryonal Fyn-associated substrate
FANCA Fanconi anemia, complementation group A
FBXO31 F-box protein 31
FLJ22184
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GLB1L2 galactosidase, beta 1-like 2
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GPR19 G protein-coupled receptor 19
GRIP2 glutamate receptor interacting protein 2
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
IL1RAPL1 interleukin 1 receptor accessory protein-like 1
ITPKA inositol-trisphosphate 3-kinase A
KLK13 kallikrein-related peptidase 13
LTB4R leukotriene B4 receptor
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MEF2D myocyte enhancer factor 2D
METTL7A methyltransferase like 7A
MIER2 mesoderm induction early response 1, family member 2
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP3 matrix metallopeptidase 3
MST1 macrophage stimulating 1
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
NFASC neurofascin
NOTCH4 notch 4
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
NRP1 neuropilin 1
NRP2 neuropilin 2
NUP214 nucleoporin 214kDa
OR10H1 olfactory receptor, family 10, subfamily H, member 1
OSGIN1 oxidative stress induced growth inhibitor 1
PALMD palmdelphin
PBX2 pre-B-cell leukemia homeobox 2
PCDHB3 protocadherin beta 3
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PGAM2 phosphoglycerate mutase 2 (muscle)
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLIN2 perilipin 2
PLK4 polo-like kinase 4
PLXNB1 plexin B1
PLXND1 plexin D1
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRB1 proline-rich protein BstNI subfamily 1
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PSG1 pregnancy specific beta-1-glycoprotein 1
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RAB28 RAB28, member RAS oncogene family
RABEP1 rabaptin, RAB GTPase binding effector protein 1
RXRB retinoid X receptor, beta
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SMAD6 SMAD family member 6
TAOK2 TAO kinase 2
TBC1D4 TBC1 domain family, member 4
TFCP2L1 transcription factor CP2-like 1
TLK1 tousled-like kinase 1
TM4SF5 transmembrane 4 L six family member 5
TP53 tumor protein p53
TRAF4 TNF receptor-associated factor 4
TSPAN32 tetraspanin 32
VPRBP Vpr (HIV-1) binding protein
ZNF287 zinc finger protein 287
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACSBG2 acyl-CoA synthetase bubblegum family member 2
AFF4 AF4/FMR2 family, member 4
AHSG alpha-2-HS-glycoprotein
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
APOBEC2 apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2
ARHGAP22 Rho GTPase activating protein 22
ARMCX4 armadillo repeat containing, X-linked 4
BDKRB1 bradykinin receptor B1
BIRC7 baculoviral IAP repeat containing 7
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C11ORF21 chromosome 11 open reading frame 21
C1ORF105 chromosome 1 open reading frame 105
CD34 CD34 molecule
CEP41 centrosomal protein 41kDa
CFAP45 cilia and flagella associated protein 45
CFAP69 cilia and flagella associated protein 69
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLCA1 chloride channel accessory 1
CLCN6 chloride channel, voltage-sensitive 6
CLSTN3 calsyntenin 3
CRY2 cryptochrome circadian clock 2
DDN dendrin
DYM dymeclin
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ELMO3 engulfment and cell motility 3
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM63A family with sequence similarity 63, member A
FBXO2 F-box protein 2
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FRMD1 FERM domain containing 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GLS2 glutaminase 2 (liver, mitochondrial)
HIST1H1D histone cluster 1, H1d
HIST1H2BM histone cluster 1, H2bm
HIST1H2BN histone cluster 1, H2bn
HIST1H4E histone cluster 1, H4e
HOXB2 homeobox B2
HSPA1L heat shock 70kDa protein 1-like
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
IDI2-AS1 IDI2 antisense RNA 1
IFNA14 interferon, alpha 14
INE1 inactivation escape 1 (non-protein coding)
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KCTD17 potassium channel tetramerization domain containing 17
KLHL29 kelch-like family member 29
LAX1 lymphocyte transmembrane adaptor 1
LIME1 Lck interacting transmembrane adaptor 1
LINC00312 long intergenic non-protein coding RNA 312
LINC00341 long intergenic non-protein coding RNA 341
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LOC257152 uncharacterized LOC257152
LOC729164 hCG1732469
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MARK1 MAP/microtubule affinity-regulating kinase 1
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MYOZ3 myozenin 3
NID2 nidogen 2 (osteonidogen)
NOL10 nucleolar protein 10
NPFFR1 neuropeptide FF receptor 1
PLA2G1B phospholipase A2, group IB (pancreas)
PLD2 phospholipase D2
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PRAMEF10 PRAME family member 10
PRF1 perforin 1 (pore forming protein)
PRSS22 protease, serine, 22
PXMP4 peroxisomal membrane protein 4, 24kDa
RAB30 RAB30, member RAS oncogene family
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF126P1 ring finger protein 126 pseudogene 1
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCD5 stearoyl-CoA desaturase 5
SIX3 SIX homeobox 3
SLC16A6 solute carrier family 16, member 6
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SYCP2 synaptonemal complex protein 2
TEX40 testis expressed 40
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TMEM74B transmembrane protein 74B
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TRIM25 tripartite motif containing 25
TRIM66 tripartite motif containing 66
TRIM9 tripartite motif containing 9
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
ZNF141 zinc finger protein 141
ZNF222 zinc finger protein 222
ZNF573 zinc finger protein 573
ZNF76 zinc finger protein 76