etiocholanolone-4298 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the etiocholanolone-4298 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ADCK2 aarF domain containing kinase 2
AHNAK AHNAK nucleoprotein
AKR1C1 aldo-keto reductase family 1, member C1
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
APLP2 amyloid beta (A4) precursor-like protein 2
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
BAX BCL2-associated X protein
BBC3 BCL2 binding component 3
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAMKV CaM kinase-like vesicle-associated
CCNO cyclin O
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CD4 CD4 molecule
CD53 CD53 molecule
CDK10 cyclin-dependent kinase 10
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
CTNNA3 catenin (cadherin-associated protein), alpha 3
CTSZ cathepsin Z
DCHS1 dachsous cadherin-related 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DPF3 D4, zinc and double PHD fingers, family 3
DZIP1 DAZ interacting zinc finger protein 1
EMILIN2 elastin microfibril interfacer 2
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
ERAP1 endoplasmic reticulum aminopeptidase 1
ESR1 estrogen receptor 1
FLJ11292
FRY furry homolog (Drosophila)
FSCN3 fascin actin-bundling protein 3, testicular
GHRHR growth hormone releasing hormone receptor
GREB1L growth regulation by estrogen in breast cancer-like
HIF3A hypoxia inducible factor 3, alpha subunit
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
IL1RN interleukin 1 receptor antagonist
IL22RA1 interleukin 22 receptor, alpha 1
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITPK1 inositol-tetrakisphosphate 1-kinase
JUN jun proto-oncogene
KAT6A K(lysine) acetyltransferase 6A
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12
KDM5A lysine (K)-specific demethylase 5A
KIR3DX1 killer cell immunoglobulin-like receptor, three domains, X1
KIRREL kin of IRRE like (Drosophila)
LARP7 La ribonucleoprotein domain family, member 7
LATS1 large tumor suppressor kinase 1
LMNA lamin A/C
LPP LIM domain containing preferred translocation partner in lipoma
MAP7D3 MAP7 domain containing 3
MAPK10 mitogen-activated protein kinase 10
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCF2L MCF.2 cell line derived transforming sequence-like
MEGF9 multiple EGF-like-domains 9
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
N4BP1 NEDD4 binding protein 1
N4BP2L1 NEDD4 binding protein 2-like 1
NEU3 sialidase 3 (membrane sialidase)
NF1 neurofibromin 1
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NOP14-AS1 NOP14 antisense RNA 1
NPY6R neuropeptide Y receptor Y6 (pseudogene)
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1
PBX2 pre-B-cell leukemia homeobox 2
PELI2 pellino E3 ubiquitin protein ligase family member 2
PMFBP1 polyamine modulated factor 1 binding protein 1
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PTPRR protein tyrosine phosphatase, receptor type, R
PVT1 Pvt1 oncogene (non-protein coding)
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RASAL2 RAS protein activator like 2
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RBM5 RNA binding motif protein 5
RET ret proto-oncogene
RIN1 Ras and Rab interactor 1
SCN10A sodium channel, voltage gated, type X alpha subunit
SEC23IP SEC23 interacting protein
SH3BP2 SH3-domain binding protein 2
SKI SKI proto-oncogene
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC35E2 solute carrier family 35, member E2
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
SPTBN1 spectrin, beta, non-erythrocytic 1
STK16 serine/threonine kinase 16
STRN3 striatin, calmodulin binding protein 3
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TIMELESS timeless circadian clock
TJP3 tight junction protein 3
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TPP1 tripeptidyl peptidase I
TRIO trio Rho guanine nucleotide exchange factor
TTC38 tetratricopeptide repeat domain 38
TTLL1 tubulin tyrosine ligase-like family member 1
WSB1 WD repeat and SOCS box containing 1
ZIM2 zinc finger, imprinted 2
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ADAM15 ADAM metallopeptidase domain 15
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANP32A-IT1 ANP32A intronic transcript 1
ARMC4 armadillo repeat containing 4
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BAHCC1 BAH domain and coiled-coil containing 1
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C17ORF80 chromosome 17 open reading frame 80
C4ORF29 chromosome 4 open reading frame 29
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC106 coiled-coil domain containing 106
CCDC7 coiled-coil domain containing 7
CCDC71 coiled-coil domain containing 71
CD82 CD82 molecule
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CDON cell adhesion associated, oncogene regulated
CEP295 centrosomal protein 295kDa
CHM choroideremia (Rab escort protein 1)
CLDN11 claudin 11
CRMP1 collapsin response mediator protein 1
DBR1 debranching RNA lariats 1
EGLN3 egl-9 family hypoxia-inducible factor 3
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ETV7 ets variant 7
EXOC5 exocyst complex component 5
FZD8 frizzled class receptor 8
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLS2 glutaminase 2 (liver, mitochondrial)
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPR22 G protein-coupled receptor 22
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GUSBP3 glucuronidase, beta pseudogene 3
HDAC11 histone deacetylase 11
HELLS helicase, lymphoid-specific
IL33 interleukin 33
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KDM5C lysine (K)-specific demethylase 5C
KDM8 lysine (K)-specific demethylase 8
KLF3 Kruppel-like factor 3 (basic)
KLHL25 kelch-like family member 25
LIG4 ligase IV, DNA, ATP-dependent
LRP2 low density lipoprotein receptor-related protein 2
LRRC37A3 leucine rich repeat containing 37, member A3
LRRC61 leucine rich repeat containing 61
MFSD11 major facilitator superfamily domain containing 11
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MMP3 matrix metallopeptidase 3
MOSPD3 motile sperm domain containing 3
MTCP1 mature T-cell proliferation 1
NOL10 nucleolar protein 10
NXPH3 neurexophilin 3
OR3A3 olfactory receptor, family 3, subfamily A, member 3
PAIP2B poly(A) binding protein interacting protein 2B
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLEKHA6 pleckstrin homology domain containing, family A member 6
PRB3 proline-rich protein BstNI subfamily 3
PROX1 prospero homeobox 1
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PSAT1 phosphoserine aminotransferase 1
PTK6 protein tyrosine kinase 6
RGS17 regulator of G-protein signaling 17
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SERGEF secretion regulating guanine nucleotide exchange factor
SGPP1 sphingosine-1-phosphate phosphatase 1
SOX21 SRY (sex determining region Y)-box 21
SP1 Sp1 transcription factor
SPRYD7 SPRY domain containing 7
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TENM1 teneurin transmembrane protein 1
TEP1 telomerase-associated protein 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TM4SF4 transmembrane 4 L six family member 4
TMEM230 transmembrane protein 230
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
ULBP2 UL16 binding protein 2
VEZT vezatin, adherens junctions transmembrane protein
WDR4 WD repeat domain 4
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
YY2 YY2 transcription factor
ZBTB44 zinc finger and BTB domain containing 44
ZBTB6 zinc finger and BTB domain containing 6
ZFYVE21 zinc finger, FYVE domain containing 21
ZNF222 zinc finger protein 222
ZNF227 zinc finger protein 227
ZNF264 zinc finger protein 264
ZNF334 zinc finger protein 334
ZNF426 zinc finger protein 426
ZNF611 zinc finger protein 611
ZNF652 zinc finger protein 652
ZNF711 zinc finger protein 711
ZNF721 zinc finger protein 721
ZW10 zw10 kinetochore protein