etodolac-2091 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the etodolac-2091 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACTN4 actinin, alpha 4
AKAP7 A kinase (PRKA) anchor protein 7
ALG12 ALG12, alpha-1,6-mannosyltransferase
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ASF1A anti-silencing function 1A histone chaperone
C17ORF53 chromosome 17 open reading frame 53
CADPS2 Ca++-dependent secretion activator 2
CAMKMT calmodulin-lysine N-methyltransferase
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
COL1A2 collagen, type I, alpha 2
COPS8 COP9 signalosome subunit 8
DLL3 delta-like 3 (Drosophila)
DPP4 dipeptidyl-peptidase 4
DSCAM Down syndrome cell adhesion molecule
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
EN2 engrailed homeobox 2
ERMAP erythroblast membrane-associated protein (Scianna blood group)
FAM3A family with sequence similarity 3, member A
FAT4 FAT atypical cadherin 4
FCHSD2 FCH and double SH3 domains 2
FGF1 fibroblast growth factor 1 (acidic)
GMEB1 glucocorticoid modulatory element binding protein 1
GPR107 G protein-coupled receptor 107
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HIST1H3G histone cluster 1, H3g
HOOK1 hook microtubule-tethering protein 1
HOXB2 homeobox B2
HOXB5 homeobox B5
HSF2 heat shock transcription factor 2
ICAM1 intercellular adhesion molecule 1
IFI6 interferon, alpha-inducible protein 6
IGL immunoglobulin lambda locus
IL1RN interleukin 1 receptor antagonist
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
IQCE IQ motif containing E
KRIT1 KRIT1, ankyrin repeat containing
KRT6A keratin 6A, type II
LUC7L2 LUC7-like 2 (S. cerevisiae)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAST2 microtubule associated serine/threonine kinase 2
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta)
MFNG MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
MUC13 mucin 13, cell surface associated
MUC3B mucin 3B, cell surface associated
NCKIPSD NCK interacting protein with SH3 domain
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PARD6A par-6 family cell polarity regulator alpha
PASK PAS domain containing serine/threonine kinase
PEX11A peroxisomal biogenesis factor 11 alpha
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PROSER1 proline and serine rich 1
PTPRR protein tyrosine phosphatase, receptor type, R
RAB33A RAB33A, member RAS oncogene family
RAI2 retinoic acid induced 2
RALBP1 ralA binding protein 1
RBL2 retinoblastoma-like 2
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
RGS4 regulator of G-protein signaling 4
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila)
RPH3AL rabphilin 3A-like (without C2 domains)
SCAPER S-phase cyclin A-associated protein in the ER
SENP6 SUMO1/sentrin specific peptidase 6
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SOAT1 sterol O-acyltransferase 1
SOCS6 suppressor of cytokine signaling 6
SOGA1 suppressor of glucose, autophagy associated 1
SURF1 surfeit 1
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TBC1D8B TBC1 domain family, member 8B (with GRAM domain)
TBKBP1 TBK1 binding protein 1
TLR2 toll-like receptor 2
TM7SF3 transmembrane 7 superfamily member 3
TRAFD1 TRAF-type zinc finger domain containing 1
TRIM29 tripartite motif containing 29
TUBA3C tubulin, alpha 3c
UNC119 unc-119 homolog (C. elegans)
UST uronyl-2-sulfotransferase
VDAC3 voltage-dependent anion channel 3
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WDR59 WD repeat domain 59
ZBTB43 zinc finger and BTB domain containing 43
ZFP30 ZFP30 zinc finger protein
ZKSCAN5 zinc finger with KRAB and SCAN domains 5
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF202 zinc finger protein 202
ZNF37BP zinc finger protein 37B, pseudogene
ZNF609 zinc finger protein 609
ZNF629 zinc finger protein 629
ZNF696 zinc finger protein 696

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ANKFY1 ankyrin repeat and FYVE domain containing 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BAHD1 bromo adjacent homology domain containing 1
BCAS3 breast carcinoma amplified sequence 3
C16ORF59 chromosome 16 open reading frame 59
C19ORF54 chromosome 19 open reading frame 54
CAPN15 calpain 15
CDK3 cyclin-dependent kinase 3
CHPF chondroitin polymerizing factor
CINP cyclin-dependent kinase 2 interacting protein
CLDN15 claudin 15
CLIC3 chloride intracellular channel 3
CLP1 cleavage and polyadenylation factor I subunit 1
COA7 cytochrome c oxidase assembly factor 7 (putative)
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
FANCC Fanconi anemia, complementation group C
FANCE Fanconi anemia, complementation group E
FMO4 flavin containing monooxygenase 4
GAMT guanidinoacetate N-methyltransferase
GNA13 guanine nucleotide binding protein (G protein), alpha 13
HYAL3 hyaluronoglucosaminidase 3
IL32 interleukin 32
ISL1 ISL LIM homeobox 1
KLF7 Kruppel-like factor 7 (ubiquitous)
LIN7B lin-7 homolog B (C. elegans)
LRRC6 leucine rich repeat containing 6
LRRC61 leucine rich repeat containing 61
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MAST3 microtubule associated serine/threonine kinase 3
MCTP2 multiple C2 domains, transmembrane 2
MOCS3 molybdenum cofactor synthesis 3
MXRA8 matrix-remodelling associated 8
NOD1 nucleotide-binding oligomerization domain containing 1
OLFML2A olfactomedin-like 2A
OSMR oncostatin M receptor
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PAQR6 progestin and adipoQ receptor family member VI
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PDGFRL platelet-derived growth factor receptor-like
PILRB paired immunoglobin-like type 2 receptor beta
PLA2G15 phospholipase A2, group XV
PLD2 phospholipase D2
POLH polymerase (DNA directed), eta
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PTCD2 pentatricopeptide repeat domain 2
RAB3A RAB3A, member RAS oncogene family
RAB4B RAB4B, member RAS oncogene family
RABL6 RAB, member RAS oncogene family-like 6
RFX7 regulatory factor X, 7
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
RUSC2 RUN and SH3 domain containing 2
SAMD9 sterile alpha motif domain containing 9
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
SIX1 SIX homeobox 1
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC41A3 solute carrier family 41, member 3
SLC46A3 solute carrier family 46, member 3
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SPAG7 sperm associated antigen 7
SSNA1 Sjogren syndrome nuclear autoantigen 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STK16 serine/threonine kinase 16
STRN striatin, calmodulin binding protein
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TEX40 testis expressed 40
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)
TKFC triokinase/FMN cyclase
TM7SF2 transmembrane 7 superfamily member 2
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TPCN1 two pore segment channel 1
TUBG2 tubulin, gamma 2
UBQLN4 ubiquilin 4
WDR33 WD repeat domain 33
WNT5B wingless-type MMTV integration site family, member 5B
ZNF350 zinc finger protein 350
ZNF606 zinc finger protein 606
ZNF654 zinc finger protein 654
ZNF669 zinc finger protein 669
ZNF671 zinc finger protein 671
ZNF84 zinc finger protein 84
ZNF862 zinc finger protein 862
ZNRD1-AS1 ZNRD1 antisense RNA 1