etodolac-7006 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the etodolac-7006 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACVR1B activin A receptor, type IB
ADCY3 adenylate cyclase 3
ADGRL1 adhesion G protein-coupled receptor L1
ADRA1D adrenoceptor alpha 1D
ALOXE3 arachidonate lipoxygenase 3
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
AR androgen receptor
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ASB1 ankyrin repeat and SOCS box containing 1
BTF3P11 basic transcription factor 3 pseudogene 11
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C7ORF43 chromosome 7 open reading frame 43
CD7 CD7 molecule
CDKL3 cyclin-dependent kinase-like 3
CHD3 chromodomain helicase DNA binding protein 3
COL14A1 collagen, type XIV, alpha 1
CORO2B coronin, actin binding protein, 2B
CUZD1 CUB and zona pellucida-like domains 1
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DAGLA diacylglycerol lipase, alpha
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
ERN2 endoplasmic reticulum to nucleus signaling 2
FBXL2 F-box and leucine-rich repeat protein 2
FCAR Fc fragment of IgA receptor
GLS2 glutaminase 2 (liver, mitochondrial)
GRB10 growth factor receptor-bound protein 10
HIST1H2BN histone cluster 1, H2bn
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IFT54 intraflagellar transport 54
IL12RB1 interleukin 12 receptor, beta 1
INADL InaD-like (Drosophila)
INPP5J inositol polyphosphate-5-phosphatase J
IPO5 importin 5
IRF5 interferon regulatory factor 5
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KAT8 K(lysine) acetyltransferase 8
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KLF9 Kruppel-like factor 9
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
KPNA5 karyopherin alpha 5 (importin alpha 6)
LHX6 LIM homeobox 6
LIG4 ligase IV, DNA, ATP-dependent
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LMBR1L limb development membrane protein 1-like
LMNB1 lamin B1
LRP12 low density lipoprotein receptor-related protein 12
LRP6 low density lipoprotein receptor-related protein 6
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MAP1A microtubule-associated protein 1A
MAP2K5 mitogen-activated protein kinase kinase 5
MAPK8 mitogen-activated protein kinase 8
MBD1 methyl-CpG binding domain protein 1
MCM3AP minichromosome maintenance complex component 3 associated protein
MEF2D myocyte enhancer factor 2D
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MMP13 matrix metallopeptidase 13
MRPL52 mitochondrial ribosomal protein L52
NEURL1 neuralized E3 ubiquitin protein ligase 1
NF2 neurofibromin 2 (merlin)
NFE2L3 nuclear factor, erythroid 2-like 3
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PCNXL2 pecanex-like 2 (Drosophila)
PEX5 peroxisomal biogenesis factor 5
PKD2L2 polycystic kidney disease 2-like 2
PKNOX1 PBX/knotted 1 homeobox 1
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRAMEF11 PRAME family member 11
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRR5 proline rich 5 (renal)
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PTPRA protein tyrosine phosphatase, receptor type, A
RAB6A RAB6A, member RAS oncogene family
RABGAP1 RAB GTPase activating protein 1
RANBP3 RAN binding protein 3
RASAL2 RAS protein activator like 2
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
S100A8 S100 calcium binding protein A8
SBNO2 strawberry notch homolog 2 (Drosophila)
SCARB2 scavenger receptor class B, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SHB Src homology 2 domain containing adaptor protein B
SIAH1 siah E3 ubiquitin protein ligase 1
SIK2 salt-inducible kinase 2
SIRT3 sirtuin 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
ST7 suppression of tumorigenicity 7
STMN3 stathmin-like 3
TADA2A transcriptional adaptor 2A
TBX19 T-box 19
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
TM4SF5 transmembrane 4 L six family member 5
TPD52 tumor protein D52
TTC33 tetratricopeptide repeat domain 33
UBQLN4 ubiquilin 4
WLS wntless Wnt ligand secretion mediator
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ABHD14A abhydrolase domain containing 14A
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ATAD5 ATPase family, AAA domain containing 5
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BAHD1 bromo adjacent homology domain containing 1
BCAS1 breast carcinoma amplified sequence 1
C14ORF132 chromosome 14 open reading frame 132
C16ORF59 chromosome 16 open reading frame 59
C5ORF45 chromosome 5 open reading frame 45
C9ORF40 chromosome 9 open reading frame 40
CA11 carbonic anhydrase XI
CALCOCO1 calcium binding and coiled-coil domain 1
CAPG capping protein (actin filament), gelsolin-like
CCNO cyclin O
CDR2L cerebellar degeneration-related protein 2-like
CENPQ centromere protein Q
CGREF1 cell growth regulator with EF-hand domain 1
CHKB choline kinase beta
CRADD CASP2 and RIPK1 domain containing adaptor with death domain
CUEDC1 CUE domain containing 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNM1 dynamin 1
DTX4 deltex 4, E3 ubiquitin ligase
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EFNA3 ephrin-A3
ERF Ets2 repressor factor
FAM111A family with sequence similarity 111, member A
FSD1 fibronectin type III and SPRY domain containing 1
FURIN furin (paired basic amino acid cleaving enzyme)
GALT galactose-1-phosphate uridylyltransferase
GLB1L2 galactosidase, beta 1-like 2
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HCFC2 host cell factor C2
HIST1H2AE histone cluster 1, H2ae
IRF7 interferon regulatory factor 7
KCNK15 potassium channel, two pore domain subfamily K, member 15
KCTD15 potassium channel tetramerization domain containing 15
KLC2 kinesin light chain 2
KLHL21 kelch-like family member 21
KPTN kaptin (actin binding protein)
KRT13 keratin 13, type I
LRRC16A leucine rich repeat containing 16A
LRRC20 leucine rich repeat containing 20
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LYPD1 LY6/PLAUR domain containing 1
LYPD3 LY6/PLAUR domain containing 3
MAGEF1 melanoma antigen family F1
MANBA mannosidase, beta A, lysosomal
METTL21B methyltransferase like 21B
METTL2B methyltransferase like 2B
MOCS3 molybdenum cofactor synthesis 3
MPI mannose phosphate isomerase
MYL5 myosin, light chain 5, regulatory
MYO1E myosin IE
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NECAB3 N-terminal EF-hand calcium binding protein 3
NKAIN1 Na+/K+ transporting ATPase interacting 1
PCBP4 poly(rC) binding protein 4
PCDHA6 protocadherin alpha 6
PELI1 pellino E3 ubiquitin protein ligase 1
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PMM1 phosphomannomutase 1
POLR1B polymerase (RNA) I polypeptide B, 128kDa
PRPF38B pre-mRNA processing factor 38B
PRSS22 protease, serine, 22
PTBP2 polypyrimidine tract binding protein 2
RABGGTA Rab geranylgeranyltransferase, alpha subunit
RABL6 RAB, member RAS oncogene family-like 6
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RBL1 retinoblastoma-like 1
RBM42 RNA binding motif protein 42
RECQL4 RecQ protein-like 4
RFTN1 raftlin, lipid raft linker 1
S100A4 S100 calcium binding protein A4
SH2B2 SH2B adaptor protein 2
SIRAL2 SIR2 antiphage like 2
SLC12A8 solute carrier family 12, member 8
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa
SOX12 SRY (sex determining region Y)-box 12
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STARD13 StAR-related lipid transfer (START) domain containing 13
TARS2 threonyl-tRNA synthetase 2, mitochondrial (putative)
TBC1D31 TBC1 domain family, member 31
TCTA T-cell leukemia translocation altered
TCTN2 tectonic family member 2
TEAD3 TEA domain family member 3
TGFB3 transforming growth factor, beta 3
TM7SF3 transmembrane 7 superfamily member 3
TRIM52 tripartite motif containing 52
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TUBA3D tubulin, alpha 3d
WWC2 WW and C2 domain containing 2
ZC3H12A zinc finger CCCH-type containing 12A
ZFHX3 zinc finger homeobox 3
ZNHIT2 zinc finger, HIT-type containing 2