etofenamate-4108 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the etofenamate-4108 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ALK anaplastic lymphoma receptor tyrosine kinase
AMPD3 adenosine monophosphate deaminase 3
AREG amphiregulin
ATF3 activating transcription factor 3
ATN1 atrophin 1
ATXN3 ataxin 3
BTN3A1 butyrophilin, subfamily 3, member A1
C3 complement component 3
CCNG2 cyclin G2
CEMIP cell migration inducing protein, hyaluronan binding
CEP112 centrosomal protein 112kDa
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLEC4E C-type lectin domain family 4, member E
CLTA clathrin, light chain A
COBLL1 cordon-bleu WH2 repeat protein-like 1
COL5A2 collagen, type V, alpha 2
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DDIT3 DNA-damage-inducible transcript 3
DFNB31 deafness, autosomal recessive 31
DOCK10 dedicator of cytokinesis 10
DUSP6 dual specificity phosphatase 6
EGR1 early growth response 1
EPHB1 EPH receptor B1
EPHB3 EPH receptor B3
FAM129A family with sequence similarity 129, member A
FHIT fragile histidine triad
FOS FBJ murine osteosarcoma viral oncogene homolog
FRMD8 FERM domain containing 8
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GAB1 GRB2-associated binding protein 1
GAS7 growth arrest-specific 7
GLDC glycine dehydrogenase (decarboxylating)
GPR137 G protein-coupled receptor 137
GPR143 G protein-coupled receptor 143
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HNRNPM heterogeneous nuclear ribonucleoprotein M
HPX hemopexin
ICA1 islet cell autoantigen 1, 69kDa
INHBE inhibin, beta E
INTS7 integrator complex subunit 7
JUN jun proto-oncogene
KCNK2 potassium channel, two pore domain subfamily K, member 2
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KIAA1107 KIAA1107
KREMEN2 kringle containing transmembrane protein 2
LEF1 lymphoid enhancer-binding factor 1
LMTK1 lemur tail kinase 1
LRRC20 leucine rich repeat containing 20
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAPK7 mitogen-activated protein kinase 7
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MFAP5 microfibrillar associated protein 5
MFSD7 major facilitator superfamily domain containing 7
MR1 major histocompatibility complex, class I-related
MUC8 mucin 8
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
OMG oligodendrocyte myelin glycoprotein
PCSK6 proprotein convertase subtilisin/kexin type 6
PHLDA1 pleckstrin homology-like domain, family A, member 1
PRDM16 PR domain containing 16
PTAFR platelet-activating factor receptor
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RGS10 regulator of G-protein signaling 10
RIN1 Ras and Rab interactor 1
RNF39 ring finger protein 39
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SERHL2 serine hydrolase-like 2
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC48A1 solute carrier family 48 (heme transporter), member 1
SNCAIP synuclein, alpha interacting protein
SNED1 sushi, nidogen and EGF-like domains 1
SPDEF SAM pointed domain containing ETS transcription factor
SPINK1 serine peptidase inhibitor, Kazal type 1
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
TBC1D19 TBC1 domain family, member 19
TEX15 testis expressed 15
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TGFA transforming growth factor, alpha
TIMP3 TIMP metallopeptidase inhibitor 3
TMEFF1 transmembrane protein with EGF-like and two follistatin-like domains 1
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TTC39A tetratricopeptide repeat domain 39A
UBOX5 U-box domain containing 5
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
ULBP1 UL16 binding protein 1
UNKL unkempt family zinc finger-like
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF682 zinc finger protein 682

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ALS2CL ALS2 C-terminal like
AOC2 amine oxidase, copper containing 2 (retina-specific)
APOD apolipoprotein D
C5AR1 complement component 5a receptor 1
CCNT1 cyclin T1
CD82 CD82 molecule
CDHR2 cadherin-related family member 2
CES3 carboxylesterase 3
CHST10 carbohydrate sulfotransferase 10
CIDEB cell death-inducing DFFA-like effector b
CLSTN2 calsyntenin 2
CPA4 carboxypeptidase A4
CTNNBL1 catenin, beta like 1
CUZD1 CUB and zona pellucida-like domains 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DCAF13 DDB1 and CUL4 associated factor 13
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
ERN2 endoplasmic reticulum to nucleus signaling 2
ETNK2 ethanolamine kinase 2
FBXL6 F-box and leucine-rich repeat protein 6
FLJ21369 uncharacterized protein FLJ21369
FOXN2 forkhead box N2
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GPATCH2L G patch domain containing 2-like
GRB7 growth factor receptor-bound protein 7
GRPR gastrin-releasing peptide receptor
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HIST1H4A histone cluster 1, H4a
HIST1H4C histone cluster 1, H4c
HIST1H4F histone cluster 1, H4f
HMGB3P1 high mobility group box 3 pseudogene 1
HMOX1 heme oxygenase 1
HP1BP3 heterochromatin protein 1, binding protein 3
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
HYI hydroxypyruvate isomerase (putative)
IFI6 interferon, alpha-inducible protein 6
INO80D INO80 complex subunit D
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
LMNB1 lamin B1
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
METTL16 methyltransferase like 16
MIS18BP1 MIS18 binding protein 1
N4BP3 NEDD4 binding protein 3
NCALD neurocalcin delta
NPY4R neuropeptide Y receptor Y4
NPY6R neuropeptide Y receptor Y6 (pseudogene)
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PAIP2B poly(A) binding protein interacting protein 2B
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PGPEP1 pyroglutamyl-peptidase I
PHEX phosphate regulating endopeptidase homolog, X-linked
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PLEKHO1 pleckstrin homology domain containing, family O member 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
POLL polymerase (DNA directed), lambda
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PROL1 proline rich, lacrimal 1
PRR14L proline rich 14-like
PRSS53 protease, serine, 53
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RFX7 regulatory factor X, 7
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF122 ring finger protein 122
RNF126P1 ring finger protein 126 pseudogene 1
RPL10L ribosomal protein L10-like
RUSC2 RUN and SH3 domain containing 2
SAMD9 sterile alpha motif domain containing 9
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SETD1A SET domain containing 1A
SIRAL2 SIR2 antiphage like 2
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPRR1B small proline-rich protein 1B
STXBP2 syntaxin binding protein 2
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TBX19 T-box 19
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TCTN2 tectonic family member 2
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
THBS3 thrombospondin 3
TPCN1 two pore segment channel 1
TTLL1 tubulin tyrosine ligase-like family member 1
UCN urocortin
UNC93B1 unc-93 homolog B1 (C. elegans)
USP36 ubiquitin specific peptidase 36
VASH2 vasohibin 2
WDR4 WD repeat domain 4
XDH xanthine dehydrogenase
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF747 zinc finger protein 747