| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the etofylline-1409 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD2 | abhydrolase domain containing 2 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| ADRBK2 | adrenergic, beta, receptor kinase 2 |
| AP3D1 | adaptor-related protein complex 3, delta 1 subunit |
| APBA2 | amyloid beta (A4) precursor protein-binding, family A, member 2 |
| ARIH2 | ariadne RBR E3 ubiquitin protein ligase 2 |
| BAX | BCL2-associated X protein |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) |
| BPHL | biphenyl hydrolase-like (serine hydrolase) |
| BRAP | BRCA1 associated protein |
| C14ORF159 | chromosome 14 open reading frame 159 |
| C2ORF68 | chromosome 2 open reading frame 68 |
| C9ORF16 | chromosome 9 open reading frame 16 |
| CA6 | carbonic anhydrase VI |
| CEP162 | centrosomal protein 162kDa |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| COPS8 | COP9 signalosome subunit 8 |
| CRMP1 | collapsin response mediator protein 1 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DHTKD1 | dehydrogenase E1 and transketolase domain containing 1 |
| DIEXF | digestive organ expansion factor homolog (zebrafish) |
| DND1 | DND microRNA-mediated repression inhibitor 1 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| ETV1 | ets variant 1 |
| FAM134B | family with sequence similarity 134, member B |
| FAM89B | family with sequence similarity 89, member B |
| FKBP9 | FK506 binding protein 9, 63 kDa |
| FN1 | fibronectin 1 |
| FSTL1 | follistatin-like 1 |
| FUZ | fuzzy planar cell polarity protein |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 |
| GGT1 | gamma-glutamyltransferase 1 |
| GPR182 | G protein-coupled receptor 182 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GSK3A | glycogen synthase kinase 3 alpha |
| HIST1H4J | histone cluster 1, H4j |
| HTRA2 | HtrA serine peptidase 2 |
| ICAM1 | intercellular adhesion molecule 1 |
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| IL9R | interleukin 9 receptor |
| JRK | Jrk homolog (mouse) |
| KHSRP | KH-type splicing regulatory protein |
| KIAA1045 | KIAA1045 |
| KLF3 | Kruppel-like factor 3 (basic) |
| LENEP | lens epithelial protein |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAP4 | microtubule-associated protein 4 |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MINK1 | misshapen-like kinase 1 |
| MLYCD | malonyl-CoA decarboxylase |
| MMP19 | matrix metallopeptidase 19 |
| N4BP1 | NEDD4 binding protein 1 |
| NADK | NAD kinase |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NIPAL2 | NIPA-like domain containing 2 |
| NKIRAS2 | NFKB inhibitor interacting Ras-like 2 |
| OXLD1 | oxidoreductase-like domain containing 1 |
| PADI1 | peptidyl arginine deiminase, type I |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 |
| PARD3 | par-3 family cell polarity regulator |
| PHACTR2 | phosphatase and actin regulator 2 |
| PLEC | plectin |
| POLG | polymerase (DNA directed), gamma |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 |
| PRELP | proline/arginine-rich end leucine-rich repeat protein |
| PRY | PTPN13-like, Y-linked |
| PTDSS2 | phosphatidylserine synthase 2 |
| RAB8B | RAB8B, member RAS oncogene family |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RARA | retinoic acid receptor, alpha |
| RET | ret proto-oncogene |
| RETN | resistin |
| RGS12 | regulator of G-protein signaling 12 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SDC2 | syndecan 2 |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C |
| SGSM2 | small G protein signaling modulator 2 |
| SHARPIN | SHANK-associated RH domain interactor |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SLC4A1 | solute carrier family 4 (anion exchanger), member 1 (Diego blood group) |
| SPN | sialophorin |
| STAR | steroidogenic acute regulatory protein |
| TAS2R1 | taste receptor, type 2, member 1 |
| TCF3 | transcription factor 3 |
| TCF4 | transcription factor 4 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) |
| TM9SF4 | transmembrane 9 superfamily protein member 4 |
| TMEM159 | transmembrane protein 159 |
| TRA | T cell receptor alpha locus |
| TSPAN32 | tetraspanin 32 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 |
| UBE3A | ubiquitin protein ligase E3A |
| XAF1 | XIAP associated factor 1 |
| ZNF783 | zinc finger family member 783 |
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 |
| ACYP1 | acylphosphatase 1, erythrocyte (common) type |
| AGO2 | argonaute RISC catalytic component 2 |
| ANKRD46 | ankyrin repeat domain 46 |
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 |
| ARMT1 | acidic residue methyltransferase 1 |
| ATAD2 | ATPase family, AAA domain containing 2 |
| ATXN2 | ataxin 2 |
| BCL10 | B-cell CLL/lymphoma 10 |
| CDC7 | cell division cycle 7 |
| CENPQ | centromere protein Q |
| CEP55 | centrosomal protein 55kDa |
| CETN3 | centrin, EF-hand protein, 3 |
| CLDN15 | claudin 15 |
| CLDND1 | claudin domain containing 1 |
| CLPX | caseinolytic mitochondrial matrix peptidase chaperone subunit |
| CPOX | coproporphyrinogen oxidase |
| CRTAP | cartilage associated protein |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 |
| DCK | deoxycytidine kinase |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 |
| DPYD | dihydropyrimidine dehydrogenase |
| DYNC1LI1 | dynein, cytoplasmic 1, light intermediate chain 1 |
| E2F6 | E2F transcription factor 6 |
| E2F8 | E2F transcription factor 8 |
| EPS15 | epidermal growth factor receptor pathway substrate 15 |
| EVL | Enah/Vasp-like |
| EXOSC9 | exosome component 9 |
| FAM222B | family with sequence similarity 222, member B |
| FOXJ2 | forkhead box J2 |
| GOLPH3L | golgi phosphoprotein 3-like |
| GPN3 | GPN-loop GTPase 3 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| ITGAV | integrin, alpha V |
| KIAA0753 | KIAA0753 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 |
| LRIF1 | ligand dependent nuclear receptor interacting factor 1 |
| LYZ | lysozyme |
| MCM10 | minichromosome maintenance complex component 10 |
| MED4 | mediator complex subunit 4 |
| METTL18 | methyltransferase like 18 |
| MNS1 | meiosis-specific nuclear structural 1 |
| MORC3 | MORC family CW-type zinc finger 3 |
| MRPL19 | mitochondrial ribosomal protein L19 |
| MTG1 | mitochondrial ribosome-associated GTPase 1 |
| MYL12B | myosin, light chain 12B, regulatory |
| MYO5C | myosin VC |
| NFE2L2 | nuclear factor, erythroid 2-like 2 |
| NHLRC2 | NHL repeat containing 2 |
| OCEL1 | occludin/ELL domain containing 1 |
| OGFRL1 | opioid growth factor receptor-like 1 |
| OSBPL11 | oxysterol binding protein-like 11 |
| OSTM1 | osteopetrosis associated transmembrane protein 1 |
| PAK1IP1 | PAK1 interacting protein 1 |
| PCTP | phosphatidylcholine transfer protein |
| PDCD5 | programmed cell death 5 |
| PEF1 | penta-EF-hand domain containing 1 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PPIP5K2 | diphosphoinositol pentakisphosphate kinase 2 |
| PRPF39 | pre-mRNA processing factor 39 |
| PTBP2 | polypyrimidine tract binding protein 2 |
| QTRTD1 | queuine tRNA-ribosyltransferase domain containing 1 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
| RBM47 | RNA binding motif protein 47 |
| RPP38 | ribonuclease P/MRP 38kDa subunit |
| RPRD1A | regulation of nuclear pre-mRNA domain containing 1A |
| RSL24D1 | ribosomal L24 domain containing 1 |
| RWDD3 | RWD domain containing 3 |
| SCAF8 | SR-related CTD-associated factor 8 |
| SEH1L | SEH1-like (S. cerevisiae) |
| SLMO2 | slowmo homolog 2 (Drosophila) |
| SMNDC1 | survival motor neuron domain containing 1 |
| SPDL1 | spindle apparatus coiled-coil protein 1 |
| STK39 | serine threonine kinase 39 |
| STXBP3 | syntaxin binding protein 3 |
| STYXL1 | serine/threonine/tyrosine interacting-like 1 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TBL3 | transducin (beta)-like 3 |
| TJP2 | tight junction protein 2 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMEM14A | transmembrane protein 14A |
| TMEM38B | transmembrane protein 38B |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| TRMT1L | tRNA methyltransferase 1 homolog (S. cerevisiae)-like |
| TSLIG2 | tRNA splicing ligase complex subunit 2 |
| TVP23B | trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| UPF2 | UPF2 regulator of nonsense transcripts homolog (yeast) |
| UPF3B | UPF3 regulator of nonsense transcripts homolog B (yeast) |
| URGCP | upregulator of cell proliferation |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| ZCCHC8 | zinc finger, CCHC domain containing 8 |
| ZEB2 | zinc finger E-box binding homeobox 2 |
| ZNF124 | zinc finger protein 124 |
| ZNF140 | zinc finger protein 140 |
| ZNF217 | zinc finger protein 217 |
| ZNF652 | zinc finger protein 652 |
