| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the etofylline-5048 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 |
| APAF1 | apoptotic peptidase activating factor 1 |
| APOC1 | apolipoprotein C-I |
| APOD | apolipoprotein D |
| ARHGAP26 | Rho GTPase activating protein 26 |
| ARSD | arylsulfatase D |
| ASIC1 | acid sensing (proton gated) ion channel 1 |
| ASIC3 | acid sensing (proton gated) ion channel 3 |
| ATF7 | activating transcription factor 7 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BMP1 | bone morphogenetic protein 1 |
| BMP7 | bone morphogenetic protein 7 |
| CD244 | CD244 molecule, natural killer cell receptor 2B4 |
| CD58 | CD58 molecule |
| CDK13 | cyclin-dependent kinase 13 |
| CHRM5 | cholinergic receptor, muscarinic 5 |
| COQ7 | coenzyme Q7 homolog, ubiquinone (yeast) |
| CREBZF | CREB/ATF bZIP transcription factor |
| DCTN1 | dynactin 1 |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 |
| DNAH7 | dynein, axonemal, heavy chain 7 |
| DOCK9 | dedicator of cytokinesis 9 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B |
| ESR1 | estrogen receptor 1 |
| FAM105A | family with sequence similarity 105, member A |
| FAM134B | family with sequence similarity 134, member B |
| FGFR1 | fibroblast growth factor receptor 1 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FKSG49 | FKSG49 |
| FMO5 | flavin containing monooxygenase 5 |
| GAL | galanin/GMAP prepropeptide |
| GAS2L1 | growth arrest-specific 2 like 1 |
| GPATCH4 | G patch domain containing 4 |
| GRB7 | growth factor receptor-bound protein 7 |
| GRM8 | glutamate receptor, metabotropic 8 |
| GSN-AS1 | GSN antisense RNA 1 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M |
| IL17RB | interleukin 17 receptor B |
| IL1R1 | interleukin 1 receptor, type I |
| KCNAB1 | potassium channel, voltage gated subfamily A regulatory beta subunit 1 |
| KIAA0319L | KIAA0319-like |
| KLF12 | Kruppel-like factor 12 |
| KLHL22 | kelch-like family member 22 |
| KYNU | kynureninase |
| LIMD1 | LIM domains containing 1 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MATN3 | matrilin 3 |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MMP11 | matrix metallopeptidase 11 |
| MMP25 | matrix metallopeptidase 25 |
| MMP3 | matrix metallopeptidase 3 |
| MPL | MPL proto-oncogene, thrombopoietin receptor |
| MST1 | macrophage stimulating 1 |
| MUC8 | mucin 8 |
| MYO9B | myosin IXB |
| NEBL | nebulette |
| NEUROD1 | neuronal differentiation 1 |
| NF1 | neurofibromin 1 |
| NFRKB | nuclear factor related to kappaB binding protein |
| NPFF | neuropeptide FF-amide peptide precursor |
| ORC5 | origin recognition complex, subunit 5 |
| PCDH7 | protocadherin 7 |
| PID1 | phosphotyrosine interaction domain containing 1 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| PLIN2 | perilipin 2 |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 |
| PRR5 | proline rich 5 (renal) |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 |
| RAB26 | RAB26, member RAS oncogene family |
| RASSF9 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 9 |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog |
| REPS1 | RALBP1 associated Eps domain containing 1 |
| RHOBTB3 | Rho-related BTB domain containing 3 |
| RPL35A | ribosomal protein L35a |
| RTCA | RNA 3'-terminal phosphate cyclase |
| SCAF4 | SR-related CTD-associated factor 4 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
| SLC16A7 | solute carrier family 16 (monocarboxylate transporter), member 7 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SNAPC5 | small nuclear RNA activating complex, polypeptide 5, 19kDa |
| SOX5 | SRY (sex determining region Y)-box 5 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| SZT2 | seizure threshold 2 homolog (mouse) |
| TM2D1 | TM2 domain containing 1 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 |
| TRAF4 | TNF receptor-associated factor 4 |
| TRIM33 | tripartite motif containing 33 |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 |
| VNN1 | vanin 1 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) |
| WNK1 | WNK lysine deficient protein kinase 1 |
| ZBTB17 | zinc finger and BTB domain containing 17 |
| ZNF518A | zinc finger protein 518A |
| Symbol | Name |
|---|---|
| ANKRD36 | ankyrin repeat domain 36 |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARL14 | ADP-ribosylation factor-like 14 |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| BMP15 | bone morphogenetic protein 15 |
| BZRAP1 | benzodiazepine receptor (peripheral) associated protein 1 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CAPN15 | calpain 15 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CD70 | CD70 molecule |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CEP131 | centrosomal protein 131kDa |
| CFAP45 | cilia and flagella associated protein 45 |
| CHRDL1 | chordin-like 1 |
| CNN1 | calponin 1, basic, smooth muscle |
| CRY2 | cryptochrome circadian clock 2 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| ERF | Ets2 repressor factor |
| EVPL | envoplakin |
| EXOSC1 | exosome component 1 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FBXO31 | F-box protein 31 |
| FUZ | fuzzy planar cell polarity protein |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HIST1H2BN | histone cluster 1, H2bn |
| HIST1H3C | histone cluster 1, H3c |
| HOXC5 | homeobox C5 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFNA17 | interferon, alpha 17 |
| KDM7A | lysine (K)-specific demethylase 7A |
| KIAA1456 | KIAA1456 |
| KIRREL | kin of IRRE like (Drosophila) |
| KLC2 | kinesin light chain 2 |
| KLK6 | kallikrein-related peptidase 6 |
| KRT31 | keratin 31, type I |
| LATS1 | large tumor suppressor kinase 1 |
| LOC257152 | uncharacterized LOC257152 |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MAP3K7CL | MAP3K7 C-terminal like |
| MAPK12 | mitogen-activated protein kinase 12 |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MLYCD | malonyl-CoA decarboxylase |
| MUC3B | mucin 3B, cell surface associated |
| NARFL | nuclear prelamin A recognition factor-like |
| NDE1 | nudE neurodevelopment protein 1 |
| NME5 | NME/NM23 family member 5 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| NXN | nucleoredoxin |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PGPEP1 | pyroglutamyl-peptidase I |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PRR7 | proline rich 7 (synaptic) |
| PRSS53 | protease, serine, 53 |
| PXMP4 | peroxisomal membrane protein 4, 24kDa |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RGS19 | regulator of G-protein signaling 19 |
| RIN1 | Ras and Rab interactor 1 |
| RNF39 | ring finger protein 39 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCAI | suppressor of cancer cell invasion |
| SCN8A | sodium channel, voltage gated, type VIII alpha subunit |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SLC18A2 | solute carrier family 18 (vesicular monoamine transporter), member 2 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 |
| SNTA1 | syntrophin, alpha 1 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| STAC | SH3 and cysteine rich domain |
| STBD1 | starch binding domain 1 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TMEM212 | transmembrane protein 212 |
| TMEM8B | transmembrane protein 8B |
| TOM1 | target of myb1 (chicken) |
| TRPC5 | transient receptor potential cation channel, subfamily C, member 5 |
| TUBA3C | tubulin, alpha 3c |
| TUBG2 | tubulin, gamma 2 |
| ZC2HC1C | zinc finger, C2HC-type containing 1C |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF141 | zinc finger protein 141 |
| ZNF32 | zinc finger protein 32 |
| ZNF358 | zinc finger protein 358 |
| ZNF552 | zinc finger protein 552 |
| ZNF639 | zinc finger protein 639 |
| ZNF747 | zinc finger protein 747 |
| ZNF768 | zinc finger protein 768 |
| ZNF862 | zinc finger protein 862 |
