etomidate-3519 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the etomidate-3519 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20
ANPEP alanyl (membrane) aminopeptidase
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ATF7IP activating transcription factor 7 interacting protein
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
BTN2A3P butyrophilin, subfamily 2, member A3, pseudogene
CA9 carbonic anhydrase IX
CACNG5 calcium channel, voltage-dependent, gamma subunit 5
CCDC57 coiled-coil domain containing 57
CCRL2 chemokine (C-C motif) receptor-like 2
CD4 CD4 molecule
CD8B CD8b molecule
CDHR2 cadherin-related family member 2
CDX2 caudal type homeobox 2
CDY1 chromodomain protein, Y-linked, 1
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CGA glycoprotein hormones, alpha polypeptide
CNN3 calponin 3, acidic
COL9A3 collagen, type IX, alpha 3
CPQ carboxypeptidase Q
CRHR2 corticotropin releasing hormone receptor 2
CXORF21 chromosome X open reading frame 21
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DCX doublecortin
DKK3 dickkopf WNT signaling pathway inhibitor 3
DMRT1 doublesex and mab-3 related transcription factor 1
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DOK4 docking protein 4
DSCAM Down syndrome cell adhesion molecule
EGF epidermal growth factor
ESR1 estrogen receptor 1
FGF18 fibroblast growth factor 18
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
GNAS GNAS complex locus
HDAC6 histone deacetylase 6
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HEXA-AS1 HEXA antisense RNA 1
ICA1 islet cell autoantigen 1, 69kDa
ICAM1 intercellular adhesion molecule 1
IFI44L interferon-induced protein 44-like
IKZF1 IKAROS family zinc finger 1 (Ikaros)
INTS3 integrator complex subunit 3
IPW imprinted in Prader-Willi syndrome (non-protein coding)
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KRT32 keratin 32, type I
KRT37 keratin 37, type I
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LECT1 leukocyte cell derived chemotaxin 1
LMTK2 lemur tyrosine kinase 2
LOC440895 two pore channel 3 pseudogene
LRRC8B leucine rich repeat containing 8 family, member B
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MASP2 mannan-binding lectin serine peptidase 2
MINK1 misshapen-like kinase 1
MYH2 myosin, heavy chain 2, skeletal muscle, adult
N4BP2L2-IT2 N4BPL2 intronic transcript 2
NCAPH2 non-SMC condensin II complex, subunit H2
NCOR2 nuclear receptor corepressor 2
NEUROD1 neuronal differentiation 1
NKX6-1 NK6 homeobox 1
NME5 NME/NM23 family member 5
NRL neural retina leucine zipper
NUP88 nucleoporin 88kDa
PCDHGA10 protocadherin gamma subfamily A, 10
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PGLYRP4 peptidoglycan recognition protein 4
PMS2P4 postmeiotic segregation increased 2 pseudogene 4
POU3F2 POU class 3 homeobox 2
PPP1R37 protein phosphatase 1, regulatory subunit 37
PPP5C protein phosphatase 5, catalytic subunit
PWAR5 Prader Willi/Angelman region RNA 5
RAB40A RAB40A, member RAS oncogene family
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RBMS2 RNA binding motif, single stranded interacting protein 2
RNF5 ring finger protein 5, E3 ubiquitin protein ligase
RPS3A ribosomal protein S3A
SAMD9 sterile alpha motif domain containing 9
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SFTPC surfactant protein C
SLAMF7 SLAM family member 7
SLC17A4 solute carrier family 17, member 4
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SNX13 sorting nexin 13
SOD3 superoxide dismutase 3, extracellular
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
STAT2 signal transducer and activator of transcription 2, 113kDa
TAOK2 TAO kinase 2
TFCP2 transcription factor CP2
THRB thyroid hormone receptor, beta
TMCC2 transmembrane and coiled-coil domain family 2
TMPRSS15 transmembrane protease, serine 15
TOP3B topoisomerase (DNA) III beta
TSKS testis-specific serine kinase substrate
TYRP1 tyrosinase-related protein 1

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ADAP1 ArfGAP with dual PH domains 1
ADGRG2 adhesion G protein-coupled receptor G2
ALPK1 alpha-kinase 1
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
APOLD1 apolipoprotein L domain containing 1
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARSB arylsulfatase B
C11ORF68 chromosome 11 open reading frame 68
C19ORF73 chromosome 19 open reading frame 73
C7ORF43 chromosome 7 open reading frame 43
CCDC121 coiled-coil domain containing 121
CHRM3 cholinergic receptor, muscarinic 3
CIC capicua transcriptional repressor
CIDEC cell death-inducing DFFA-like effector c
CNKSR1 connector enhancer of kinase suppressor of Ras 1
COG4 component of oligomeric golgi complex 4
CRYBB2P1 crystallin, beta B2 pseudogene 1
ECHDC3 enoyl CoA hydratase domain containing 3
ECSIT ECSIT signalling integrator
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERCC5 excision repair cross-complementation group 5
FBRS fibrosin
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FKBP1B FK506 binding protein 1B, 12.6 kDa
FLJ22184
FLRT3 fibronectin leucine rich transmembrane protein 3
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GUSBP3 glucuronidase, beta pseudogene 3
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3
HHLA3 HERV-H LTR-associating 3
HOXC10 homeobox C10
INPP1 inositol polyphosphate-1-phosphatase
IRF2 interferon regulatory factor 2
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KIF13A kinesin family member 13A
KLF3 Kruppel-like factor 3 (basic)
KRT8P12 keratin 8 pseudogene 12
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LHX6 LIM homeobox 6
LRP3 low density lipoprotein receptor-related protein 3
LRP5 low density lipoprotein receptor-related protein 5
METTL4 methyltransferase like 4
MKNK2 MAP kinase interacting serine/threonine kinase 2
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
NABP2 nucleic acid binding protein 2
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NKX3-2 NK3 homeobox 2
NT5DC3 5'-nucleotidase domain containing 3
OLFML2A olfactomedin-like 2A
OTUD3 OTU deubiquitinase 3
PACS1 phosphofurin acidic cluster sorting protein 1
PC pyruvate carboxylase
PDGFA platelet-derived growth factor alpha polypeptide
PELI1 pellino E3 ubiquitin protein ligase 1
PGPEP1 pyroglutamyl-peptidase I
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PNPLA6 patatin-like phospholipase domain containing 6
PTP4A3 protein tyrosine phosphatase type IVA, member 3
RECQL4 RecQ protein-like 4
RPGRIP1L RPGRIP1-like
RUSC2 RUN and SH3 domain containing 2
SAYSD1 SAYSVFN motif domain containing 1
SCO2 SCO2 cytochrome c oxidase assembly protein
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SGMS1 sphingomyelin synthase 1
SIRT6 sirtuin 6
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SPATA2L spermatogenesis associated 2-like
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STX1A syntaxin 1A (brain)
SYNGR3 synaptogyrin 3
TCP10 t-complex 10
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TM6SF1 transmembrane 6 superfamily member 1
TMEM53 transmembrane protein 53
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
USB1 U6 snRNA biogenesis 1
VAX2 ventral anterior homeobox 2
WDR4 WD repeat domain 4
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF16 zinc finger protein 16
ZNF280D zinc finger protein 280D
ZNF32 zinc finger protein 32
ZNF480 zinc finger protein 480
ZNF510 zinc finger protein 510
ZNF516 zinc finger protein 516
ZNF573 zinc finger protein 573
ZNF606 zinc finger protein 606
ZNF652 zinc finger protein 652
ZNF721 zinc finger protein 721
ZNF74 zinc finger protein 74