| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the etoposide-1626 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| ATF3 | activating transcription factor 3 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 |
| BCL3 | B-cell CLL/lymphoma 3 |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| BTG2 | BTG family, member 2 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CCL4 | chemokine (C-C motif) ligand 4 |
| CCNE2 | cyclin E2 |
| CD14 | CD14 molecule |
| CD58 | CD58 molecule |
| CD83 | CD83 molecule |
| CD86 | CD86 molecule |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CLDND1 | claudin domain containing 1 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYLD | cylindromatosis (turban tumor syndrome) |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DHX38 | DEAH (Asp-Glu-Ala-His) box polypeptide 38 |
| DUSP2 | dual specificity phosphatase 2 |
| EGR1 | early growth response 1 |
| EGR2 | early growth response 2 |
| ELMO2 | engulfment and cell motility 2 |
| EPAS1 | endothelial PAS domain protein 1 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| FILIP1L | filamin A interacting protein 1-like |
| FPR1 | formyl peptide receptor 1 |
| FTH1 | ferritin, heavy polypeptide 1 |
| FTH1P5 | ferritin, heavy polypeptide 1 pseudogene 5 |
| G0S2 | G0/G1 switch 2 |
| GCH1 | GTP cyclohydrolase 1 |
| GPR183 | G protein-coupled receptor 183 |
| H2BFS | H2B histone family, member S (pseudogene) |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST1H2BD | histone cluster 1, H2bd |
| HIST1H2BE | histone cluster 1, H2be |
| HIST1H4E | histone cluster 1, H4e |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| IER3 | immediate early response 3 |
| IFI16 | interferon, gamma-inducible protein 16 |
| IFI44 | interferon-induced protein 44 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIH1 | interferon induced with helicase C domain 1 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 |
| IL10RA | interleukin 10 receptor, alpha |
| IL1B | interleukin 1, beta |
| IL23A | interleukin 23, alpha subunit p19 |
| IL24 | interleukin 24 |
| IL6ST | interleukin 6 signal transducer |
| IRF7 | interferon regulatory factor 7 |
| ISG15 | ISG15 ubiquitin-like modifier |
| JUN | jun proto-oncogene |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) |
| KYNU | kynureninase |
| LPXN | leupaxin |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| MX1 | MX dynamin-like GTPase 1 |
| MX2 | MX dynamin-like GTPase 2 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NINJ1 | ninjurin 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| NXF1 | nuclear RNA export factor 1 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PLSCR1 | phospholipid scramblase 1 |
| PPIF | peptidylprolyl isomerase F |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| PPP1R16B | protein phosphatase 1, regulatory subunit 16B |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 |
| PTX3 | pentraxin 3, long |
| RAB8B | RAB8B, member RAS oncogene family |
| REL | v-rel avian reticuloendotheliosis viral oncogene homolog |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RIT1 | Ras-like without CAAX 1 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SOD2 | superoxide dismutase 2, mitochondrial |
| SQSTM1 | sequestosome 1 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa |
| TFEC | transcription factor EC |
| THBS1 | thrombospondin 1 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| Symbol | Name |
|---|---|
| ADCK3 | aarF domain containing kinase 3 |
| ADM | adrenomedullin |
| ADRB2 | adrenoceptor beta 2, surface |
| ARHGAP15 | Rho GTPase activating protein 15 |
| ARHGAP17 | Rho GTPase activating protein 17 |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
| ATAD2B | ATPase family, AAA domain containing 2B |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B |
| C19ORF24 | chromosome 19 open reading frame 24 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 |
| CBFA2T3 | core-binding factor, runt domain, alpha subunit 2; translocated to, 3 |
| CCDC86 | coiled-coil domain containing 86 |
| CCNB1 | cyclin B1 |
| CDC20 | cell division cycle 20 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CECR5 | cat eye syndrome chromosome region, candidate 5 |
| CELF2 | CUGBP, Elav-like family member 2 |
| CENPE | centromere protein E, 312kDa |
| CENPF | centromere protein F, 350/400kDa |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 |
| COQ2 | coenzyme Q2 4-hydroxybenzoate polyprenyltransferase |
| CSK | c-src tyrosine kinase |
| DCPS | decapping enzyme, scavenger |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 |
| DEAF1 | DEAF1 transcription factor |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| FAM216A | family with sequence similarity 216, member A |
| FBXL4 | F-box and leucine-rich repeat protein 4 |
| FLT3 | fms-related tyrosine kinase 3 |
| FOXK2 | forkhead box K2 |
| GFI1 | growth factor independent 1 transcription repressor |
| GPD1L | glycerol-3-phosphate dehydrogenase 1-like |
| GRAMD4 | GRAM domain containing 4 |
| HILPDA | hypoxia inducible lipid droplet-associated |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) |
| IDH1 | isocitrate dehydrogenase 1 (NADP+), soluble |
| IFT57 | intraflagellar transport 57 |
| IMPA2 | inositol(myo)-1(or 4)-monophosphatase 2 |
| IMPACT | impact RWD domain protein |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| KIAA0196 | KIAA0196 |
| KIAA0930 | KIAA0930 |
| KIF20A | kinesin family member 20A |
| LAMP5 | lysosomal-associated membrane protein family, member 5 |
| LAS1L | LAS1-like (S. cerevisiae) |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 |
| LRMP | lymphoid-restricted membrane protein |
| MCM3AP-AS1 | MCM3AP antisense RNA 1 |
| MFSD10 | major facilitator superfamily domain containing 10 |
| MID1IP1 | MID1 interacting protein 1 |
| MINA | MYC induced nuclear antigen |
| MLST8 | MTOR associated protein, LST8 homolog (S. cerevisiae) |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
| MPO | myeloperoxidase |
| MRPL4 | mitochondrial ribosomal protein L4 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| MXI1 | MAX interactor 1, dimerization protein |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| MYLIP | myosin regulatory light chain interacting protein |
| NDFIP1 | Nedd4 family interacting protein 1 |
| NEFH | neurofilament, heavy polypeptide |
| NUDT1 | nudix (nucleoside diphosphate linked moiety X)-type motif 1 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PIGN | phosphatidylinositol glycan anchor biosynthesis, class N |
| PLK1 | polo-like kinase 1 |
| PNO1 | partner of NOB1 homolog (S. cerevisiae) |
| PRMT3 | protein arginine methyltransferase 3 |
| PRTN3 | proteinase 3 |
| PSRC1 | proline/serine-rich coiled-coil 1 |
| PTTG1 | pituitary tumor-transforming 1 |
| PUS7 | pseudouridylate synthase 7 (putative) |
| RABEPK | Rab9 effector protein with kelch motifs |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 |
| RHOF | ras homolog family member F (in filopodia) |
| RPP40 | ribonuclease P/MRP 40kDa subunit |
| RRP1 | ribosomal RNA processing 1 |
| SELP | selectin P (granule membrane protein 140kDa, antigen CD62) |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 |
| STEAP3 | STEAP family member 3, metalloreductase |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| THBS4 | thrombospondin 4 |
| TIMM10 | translocase of inner mitochondrial membrane 10 homolog (yeast) |
| TIPRL | TOR signaling pathway regulator |
| TNS3 | tensin 3 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
| TPCN1 | two pore segment channel 1 |
| TXNDC15 | thioredoxin domain containing 15 |
| UBE2C | ubiquitin-conjugating enzyme E2C |
| USP6 | ubiquitin specific peptidase 6 |
| WDR43 | WD repeat domain 43 |
| ZNF395 | zinc finger protein 395 |
| ZNF516 | zinc finger protein 516 |
