| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the etoposide-5027 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTA2 | actin, alpha 2, smooth muscle, aorta |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 |
| APC | adenomatous polyposis coli |
| ASTN2 | astrotactin 2 |
| BCL6 | B-cell CLL/lymphoma 6 |
| BEX4 | brain expressed, X-linked 4 |
| BLNK | B-cell linker |
| BTG2 | BTG family, member 2 |
| CCNG2 | cyclin G2 |
| CCNK | cyclin K |
| CDK20 | cyclin-dependent kinase 20 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CEL | carboxyl ester lipase |
| CEP164 | centrosomal protein 164kDa |
| CES2 | carboxylesterase 2 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CPT2 | carnitine palmitoyltransferase 2 |
| CRKL | v-crk avian sarcoma virus CT10 oncogene homolog-like |
| CRY2 | cryptochrome circadian clock 2 |
| CUL7 | cullin 7 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 |
| DDB2 | damage-specific DNA binding protein 2, 48kDa |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DGKA | diacylglycerol kinase, alpha 80kDa |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
| ELN | elastin |
| EXOC7 | exocyst complex component 7 |
| FAM214B | family with sequence similarity 214, member B |
| FAS | Fas cell surface death receptor |
| FBXO31 | F-box protein 31 |
| FDXR | ferredoxin reductase |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FMO5 | flavin containing monooxygenase 5 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GM2A | GM2 ganglioside activator |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GPR87 | G protein-coupled receptor 87 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| HIPK3 | homeodomain interacting protein kinase 3 |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KLF9 | Kruppel-like factor 9 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LIF | leukemia inhibitory factor |
| LIMK2 | LIM domain kinase 2 |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MAP2 | microtubule-associated protein 2 |
| MAP3K12 | mitogen-activated protein kinase kinase kinase 12 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MST1 | macrophage stimulating 1 |
| MTCP1 | mature T-cell proliferation 1 |
| MUC3A | mucin 3A, cell surface associated |
| MXD4 | MAX dimerization protein 4 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NFX1 | nuclear transcription factor, X-box binding 1 |
| NHLH2 | nescient helix loop helix 2 |
| NOL12 | nucleolar protein 12 |
| OGFR | opioid growth factor receptor |
| PCDHB13 | protocadherin beta 13 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PITPNM1 | phosphatidylinositol transfer protein, membrane-associated 1 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PROCR | protein C receptor, endothelial |
| RALGDS | ral guanine nucleotide dissociation stimulator |
| RGS20 | regulator of G-protein signaling 20 |
| RND1 | Rho family GTPase 1 |
| S100A8 | S100 calcium binding protein A8 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SESN1 | sestrin 1 |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SLC52A1 | solute carrier family 52 (riboflavin transporter), member 1 |
| SP1 | Sp1 transcription factor |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TAPBP | TAP binding protein (tapasin) |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TIGAR | TP53 induced glycolysis regulatory phosphatase |
| TM7SF3 | transmembrane 7 superfamily member 3 |
| TMEM40 | transmembrane protein 40 |
| TMEM53 | transmembrane protein 53 |
| TMEM63A | transmembrane protein 63A |
| TNFRSF10C | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain |
| TP53I3 | tumor protein p53 inducible protein 3 |
| TRIM3 | tripartite motif containing 3 |
| TTLL3 | tubulin tyrosine ligase-like family member 3 |
| UBE2H | ubiquitin-conjugating enzyme E2H |
| XPC | xeroderma pigmentosum, complementation group C |
| YIPF4 | Yip1 domain family, member 4 |
| ZFP37 | ZFP37 zinc finger protein |
| ZMAT3 | zinc finger, matrin-type 3 |
| ZNF750 | zinc finger protein 750 |
| Symbol | Name |
|---|---|
| ARHGAP11A | Rho GTPase activating protein 11A |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
| AURKB | aurora kinase B |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B |
| CCDC85C | coiled-coil domain containing 85C |
| CCNA2 | cyclin A2 |
| CCNB1 | cyclin B1 |
| CDC20 | cell division cycle 20 |
| CDCA3 | cell division cycle associated 3 |
| CDK3 | cyclin-dependent kinase 3 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 |
| CENPE | centromere protein E, 312kDa |
| CENPF | centromere protein F, 350/400kDa |
| CEP55 | centrosomal protein 55kDa |
| CEP72 | centrosomal protein 72kDa |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| DBF4 | DBF4 zinc finger |
| DEPDC1 | DEP domain containing 1 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| DSCAM | Down syndrome cell adhesion molecule |
| DUSP2 | dual specificity phosphatase 2 |
| DYSF | dysferlin |
| E2F8 | E2F transcription factor 8 |
| ERCC6L | excision repair cross-complementation group 6-like |
| ESPL1 | extra spindle pole bodies homolog 1 (S. cerevisiae) |
| FAM64A | family with sequence similarity 64, member A |
| GAB2 | GRB2-associated binding protein 2 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GPSM2 | G-protein signaling modulator 2 |
| GRTP1 | growth hormone regulated TBC protein 1 |
| HIST1H2AG | histone cluster 1, H2ag |
| HIST1H2BJ | histone cluster 1, H2bj |
| HIST1H3B | histone cluster 1, H3b |
| HJURP | Holliday junction recognition protein |
| HMGB2 | high mobility group box 2 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| IFRD1 | interferon-related developmental regulator 1 |
| IFT140 | intraflagellar transport 140 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KIAA0319L | KIAA0319-like |
| KIF11 | kinesin family member 11 |
| KIF14 | kinesin family member 14 |
| KIF15 | kinesin family member 15 |
| KIF18A | kinesin family member 18A |
| KIF20A | kinesin family member 20A |
| KIF20B | kinesin family member 20B |
| KIF23 | kinesin family member 23 |
| KIF4A | kinesin family member 4A |
| KLHL36 | kelch-like family member 36 |
| LHX6 | LIM homeobox 6 |
| LMNB1 | lamin B1 |
| MATK | megakaryocyte-associated tyrosine kinase |
| MKI67 | marker of proliferation Ki-67 |
| MSI1 | musashi RNA-binding protein 1 |
| NCAPG | non-SMC condensin I complex, subunit G |
| NCAPH | non-SMC condensin I complex, subunit H |
| NDC80 | NDC80 kinetochore complex component |
| NDE1 | nudE neurodevelopment protein 1 |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) |
| NEK2 | NIMA-related kinase 2 |
| NME5 | NME/NM23 family member 5 |
| PER3 | period circadian clock 3 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PLK1 | polo-like kinase 1 |
| PPP6R2 | protein phosphatase 6, regulatory subunit 2 |
| PRC1 | protein regulator of cytokinesis 1 |
| PRR11 | proline rich 11 |
| PSRC1 | proline/serine-rich coiled-coil 1 |
| PTTG1 | pituitary tumor-transforming 1 |
| RACGAP1 | Rac GTPase activating protein 1 |
| RECQL4 | RecQ protein-like 4 |
| RNF2 | ring finger protein 2 |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| SIX1 | SIX homeobox 1 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SPAG5 | sperm associated antigen 5 |
| STIL | SCL/TAL1 interrupting locus |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| SYBU | syntabulin (syntaxin-interacting) |
| TACC3 | transforming, acidic coiled-coil containing protein 3 |
| TCHH | trichohyalin |
| TEX40 | testis expressed 40 |
| TPK1 | thiamin pyrophosphokinase 1 |
| TPX2 | TPX2, microtubule-associated |
| TRABD | TraB domain containing |
| TROAP | trophinin associated protein |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TTK | TTK protein kinase |
| TUBA3C | tubulin, alpha 3c |
| TUBA4B | tubulin, alpha 4b |
| UBE2C | ubiquitin-conjugating enzyme E2C |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| XK | X-linked Kx blood group |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZNF165 | zinc finger protein 165 |
| ZNF639 | zinc finger protein 639 |
