ets1 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description v-ets avian erythroblastosis virus E26 oncogene homolog 1|This gene encodes a member of the ETS family of transcription factors, which are defined by the presence of a conserved ETS DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T in target genes. These proteins function either as transcriptional activators or repressors of numerous genes, and are involved in stem cell development, cell senescence and death, and tumorigenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011] (NCBI Entrez Gene Database, 2113)
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Genes

142 genes co-occuring with the biological term ets1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACAN aggrecan
AIRE autoimmune regulator
ANGPT2 angiopoietin 2
AR androgen receptor
ARNT aryl hydrocarbon receptor nuclear translocator
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ATXN2 ataxin 2
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5
BAX BCL2-associated X protein
BMP4 bone morphogenetic protein 4
C11ORF30 chromosome 11 open reading frame 30
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCND1 cyclin D1
CCND3 cyclin D3
CD226 CD226 molecule
CD82 CD82 molecule
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CHUK conserved helix-loop-helix ubiquitous kinase
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
COL1A1 collagen, type I, alpha 1
CRYAB crystallin, alpha B
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CTGF connective tissue growth factor
CTSB cathepsin B
ELK1 ELK1, member of ETS oncogene family
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
EPAS1 endothelial PAS domain protein 1
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
ESRRA estrogen-related receptor alpha
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
F3 coagulation factor III (thromboplastin, tissue factor)
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FLT4 fms-related tyrosine kinase 4
FLVCR1 feline leukemia virus subgroup C cellular receptor 1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GATA3 GATA binding protein 3
GFI1 growth factor independent 1 transcription repressor
GHR growth hormone receptor
GRP gastrin-releasing peptide
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HOXA10 homeobox A10
HOXB7 homeobox B7
HRH2 histamine receptor H2
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
ICAM1 intercellular adhesion molecule 1
IGK immunoglobulin kappa locus
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL15 interleukin 15
IL18 interleukin 18
IL2 interleukin 2
IL21 interleukin 21
IL5 interleukin 5
IRF1 interferon regulatory factor 1
IRF5 interferon regulatory factor 5
ITGA10 integrin, alpha 10
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
JUN jun proto-oncogene
KDR kinase insert domain receptor
KIAA1524 KIAA1524
LTB lymphotoxin beta (TNF superfamily, member 3)
MAP2K2 mitogen-activated protein kinase kinase 2
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MCL1 myeloid cell leukemia 1
MIR125B1 microRNA 125b-1
MIR125B2 microRNA 125b-2
MIR126 microRNA 126
MIR146A microRNA 146a
MIR155 microRNA 155
MIR192 microRNA 192
MIR196A1 microRNA 196a-1
MIR196A2 microRNA 196a-2
MIR200B microRNA 200b
MIR222 microRNA 222
MIR31 microRNA 31
MKNK1 MAP kinase interacting serine/threonine kinase 1
MMP1 matrix metallopeptidase 1
MMP13 matrix metallopeptidase 13
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NF1 neurofibromin 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NKX3-1 NK3 homeobox 1
NME1 NME/NM23 nucleoside diphosphate kinase 1
NMI N-myc (and STAT) interactor
PARP1 poly (ADP-ribose) polymerase 1
PAX5 paired box 5
PDGFB platelet-derived growth factor beta polypeptide
PDGFD platelet derived growth factor D
PIAS4 protein inhibitor of activated STAT, 4
PIM3 Pim-3 proto-oncogene, serine/threonine kinase
POU1F1 POU class 1 homeobox 1
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PRDX6 peroxiredoxin 6
PRKCA protein kinase C, alpha
PTHLH parathyroid hormone-like hormone
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
RHOC ras homolog family member C
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RUNX1 runt-related transcription factor 1
SELE selectin E
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SNAI1 snail family zinc finger 1
SP1 Sp1 transcription factor
SP100 SP100 nuclear antigen
SPI1 Spi-1 proto-oncogene
SPP1 secreted phosphoprotein 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT4 signal transducer and activator of transcription 4
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
TAL1 T-cell acute lymphocytic leukemia 1
TBXA2R thromboxane A2 receptor
TDP2 tyrosyl-DNA phosphodiesterase 2
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFAP2D transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
TGFB1 transforming growth factor, beta 1
THBD thrombomodulin
TLX1 T-cell leukemia homeobox 1
TLX3 T-cell leukemia homeobox 3
TMEM8B transmembrane protein 8B
TNC tenascin C
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNIP1 TNFAIP3 interacting protein 1
TP53 tumor protein p53
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
WDFY4 WDFY family member 4
WT1 Wilms tumor 1
XBP1 X-box binding protein 1
ZBTB7A zinc finger and BTB domain containing 7A