etynodiol-3102 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the etynodiol-3102 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
ACSL1 acyl-CoA synthetase long-chain family member 1
ADORA3 adenosine A3 receptor
AGTR2 angiotensin II receptor, type 2
ALS2CL ALS2 C-terminal like
AMDHD2 amidohydrolase domain containing 2
ANO2 anoctamin 2, calcium activated chloride channel
AREG amphiregulin
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
BIN1 bridging integrator 1
CABP2 calcium binding protein 2
CCL16 chemokine (C-C motif) ligand 16
CCL20 chemokine (C-C motif) ligand 20
CCNA1 cyclin A1
CD163 CD163 molecule
CD80 CD80 molecule
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CHI3L2 chitinase 3-like 2
CPM carboxypeptidase M
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1
CSNK1E casein kinase 1, epsilon
CTNS cystinosin, lysosomal cystine transporter
DAPK1 death-associated protein kinase 1
DKK2 dickkopf WNT signaling pathway inhibitor 2
DKK3 dickkopf WNT signaling pathway inhibitor 3
DLC1 DLC1 Rho GTPase activating protein
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DUSP1 dual specificity phosphatase 1
ELMO3 engulfment and cell motility 3
FAM65B family with sequence similarity 65, member B
FER1L4 fer-1-like family member 4, pseudogene (functional)
FKBP5 FK506 binding protein 5
FLT3 fms-related tyrosine kinase 3
FOXO1 forkhead box O1
FPR1 formyl peptide receptor 1
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GNLY granulysin
GOSR2 golgi SNAP receptor complex member 2
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
IL13RA1 interleukin 13 receptor, alpha 1
IL1R1 interleukin 1 receptor, type I
IL1R2 interleukin 1 receptor, type II
IL24 interleukin 24
IL27RA interleukin 27 receptor, alpha
ISG20 interferon stimulated exonuclease gene 20kDa
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
ITPKA inositol-trisphosphate 3-kinase A
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KHK ketohexokinase (fructokinase)
KLF12 Kruppel-like factor 12
KLF9 Kruppel-like factor 9
KRT33A keratin 33A, type I
LAMB3 laminin, beta 3
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LPL lipoprotein lipase
LRRK1 leucine-rich repeat kinase 1
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MCM3AP minichromosome maintenance complex component 3 associated protein
METTL7A methyltransferase like 7A
MMP7 matrix metallopeptidase 7
MPDZ multiple PDZ domain protein
MT1E metallothionein 1E
MT1G metallothionein 1G
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MT2A metallothionein 2A
NMT2 N-myristoyltransferase 2
OLAH oleoyl-ACP hydrolase
OVGP1 oviductal glycoprotein 1, 120kDa
PDLIM4 PDZ and LIM domain 4
PER1 period circadian clock 1
PIP prolactin-induced protein
PPT2 palmitoyl-protein thioesterase 2
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
RHOH ras homolog family member H
RMND5B required for meiotic nuclear division 5 homolog B (S. cerevisiae)
SCN10A sodium channel, voltage gated, type X alpha subunit
SDC2 syndecan 2
SH2D4A SH2 domain containing 4A
SIX3 SIX homeobox 3
SLAMF1 signaling lymphocytic activation molecule family member 1
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12
SOCS1 suppressor of cytokine signaling 1
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
TACR1 tachykinin receptor 1
TEK TEK tyrosine kinase, endothelial
THBS1 thrombospondin 1
TLR2 toll-like receptor 2
TONSL tonsoku-like, DNA repair protein
TSC22D3 TSC22 domain family, member 3
TULP1 tubby like protein 1
VNN1 vanin 1
VSIG4 V-set and immunoglobulin domain containing 4
ZBTB16 zinc finger and BTB domain containing 16

decreased expression

Symbol Name
ADM adrenomedullin
ANKZF1 ankyrin repeat and zinc finger domain containing 1
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
ARG1 arginase 1
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATF3 activating transcription factor 3
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BEND5 BEN domain containing 5
BHLHE40 basic helix-loop-helix family, member e40
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CA5BP1 carbonic anhydrase VB pseudogene 1
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCL2 chemokine (C-C motif) ligand 2
CD83 CD83 molecule
CDCP1 CUB domain containing protein 1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CECR1 cat eye syndrome chromosome region, candidate 1
CORT cortistatin
CXCL8 chemokine (C-X-C motif) ligand 8
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
EGR2 early growth response 2
ENO2 enolase 2 (gamma, neuronal)
FAM127B family with sequence similarity 127, member B
FAM53C family with sequence similarity 53, member C
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FILIP1L filamin A interacting protein 1-like
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GEMIN8 gem (nuclear organelle) associated protein 8
GPR18 G protein-coupled receptor 18
GPR19 G protein-coupled receptor 19
GSDMD gasdermin D
HCAR3 hydroxycarboxylic acid receptor 3
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HILPDA hypoxia inducible lipid droplet-associated
HIST1H3G histone cluster 1, H3g
HYMAI hydatidiform mole associated and imprinted (non-protein coding)
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
IL1B interleukin 1, beta
ITGA10 integrin, alpha 10
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KDM3A lysine (K)-specific demethylase 3A
KIF24 kinesin family member 24
KLF10 Kruppel-like factor 10
KPTN kaptin (actin binding protein)
LIMD2 LIM domain containing 2
LRP3 low density lipoprotein receptor-related protein 3
LTC4S leukotriene C4 synthase
LZTR1 leucine-zipper-like transcription regulator 1
MCRS1 microspherule protein 1
MFSD6 major facilitator superfamily domain containing 6
MON1B MON1 secretory trafficking family member B
MYO1E myosin IE
NCS1 neuronal calcium sensor 1
NDRG1 N-myc downstream regulated 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NLK nemo-like kinase
NOD2 nucleotide-binding oligomerization domain containing 2
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PANX1 pannexin 1
PEX26 peroxisomal biogenesis factor 26
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PGP phosphoglycolate phosphatase
PHACTR1 phosphatase and actin regulator 1
PLEK pleckstrin
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PNOC prepronociceptin
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RCAN3 RCAN family member 3
RGS13 regulator of G-protein signaling 13
RGS16 regulator of G-protein signaling 16
RGS2 regulator of G-protein signaling 2
RHOBTB2 Rho-related BTB domain containing 2
RNF122 ring finger protein 122
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SPATS2 spermatogenesis associated, serine-rich 2
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STX11 syntaxin 11
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAS2R10 taste receptor, type 2, member 10
TESK2 testis-specific kinase 2
TM7SF2 transmembrane 7 superfamily member 2
TMEM45A transmembrane protein 45A
TPBG trophoblast glycoprotein
TRDMT1 tRNA aspartic acid methyltransferase 1
TRIM36 tripartite motif containing 36
ULBP2 UL16 binding protein 2
ULK1 unc-51 like autophagy activating kinase 1
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
ZHX2 zinc fingers and homeoboxes 2
ZNF280B zinc finger protein 280B
ZNF395 zinc finger protein 395
ZNF654 zinc finger protein 654
ZSCAN31 zinc finger and SCAN domain containing 31