eucatropine-2556 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the eucatropine-2556 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ALDOB aldolase B, fructose-bisphosphate
AMELX amelogenin, X-linked
ANK2 ankyrin 2, neuronal
APOC1 apolipoprotein C-I
BMP6 bone morphogenetic protein 6
BMP7 bone morphogenetic protein 7
BTD biotinidase
C1QTNF1 C1q and tumor necrosis factor related protein 1
C9ORF116 chromosome 9 open reading frame 116
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CCDC181 coiled-coil domain containing 181
CD22 CD22 molecule
CD80 CD80 molecule
CEND1 cell cycle exit and neuronal differentiation 1
CIITA class II, major histocompatibility complex, transactivator
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
CLDN17 claudin 17
CLIC3 chloride intracellular channel 3
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CNR2 cannabinoid receptor 2 (macrophage)
COMMD4 COMM domain containing 4
CRMP1 collapsin response mediator protein 1
CSNK1G1 casein kinase 1, gamma 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DRD2 dopamine receptor D2
DXO decapping exoribonuclease
EGFR epidermal growth factor receptor
EMC3 ER membrane protein complex subunit 3
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FAXDC2 fatty acid hydroxylase domain containing 2
FGF12 fibroblast growth factor 12
FGL1 fibrinogen-like 1
FLJ11292
FN1 fibronectin 1
FST follistatin
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GALR3 galanin receptor 3
GRM6 glutamate receptor, metabotropic 6
GSK3A glycogen synthase kinase 3 alpha
GTPBP1 GTP binding protein 1
HAND2-AS1 HAND2 antisense RNA 1 (head to head)
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HNF1B HNF1 homeobox B
HOXC10 homeobox C10
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
IAPP islet amyloid polypeptide
IGHM immunoglobulin heavy constant mu
IL27RA interleukin 27 receptor, alpha
IRF4 interferon regulatory factor 4
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
KRT3 keratin 3, type II
KYNU kynureninase
LECT1 leukocyte cell derived chemotaxin 1
LRRN2 leucine rich repeat neuronal 2
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2
MAPK10 mitogen-activated protein kinase 10
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MSR1 macrophage scavenger receptor 1
MTRF1L mitochondrial translational release factor 1-like
MUC8 mucin 8
NBEA neurobeachin
NEK1 NIMA-related kinase 1
NRCAM neuronal cell adhesion molecule
P4HA2 prolyl 4-hydroxylase, alpha polypeptide II
PDE4DIP phosphodiesterase 4D interacting protein
PDGFB platelet-derived growth factor beta polypeptide
PDGFRL platelet-derived growth factor receptor-like
PIGO phosphatidylinositol glycan anchor biosynthesis, class O
PKP3 plakophilin 3
PLA2G3 phospholipase A2, group III
PLCD1 phospholipase C, delta 1
POU3F1 POU class 3 homeobox 1
PTCRA pre T-cell antigen receptor alpha
PTK2B protein tyrosine kinase 2 beta
PVT1 Pvt1 oncogene (non-protein coding)
RHOB ras homolog family member B
RRP1B ribosomal RNA processing 1B
SERHL2 serine hydrolase-like 2
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SNN stannin
SOX2 SRY (sex determining region Y)-box 2
SYBU syntabulin (syntaxin-interacting)
TBC1D30 TBC1 domain family, member 30
TEX13A testis expressed 13A
TJAP1 tight junction associated protein 1 (peripheral)
TMEM140 transmembrane protein 140
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TSC2 tuberous sclerosis 2
ZBTB38 zinc finger and BTB domain containing 38
ZC3H7B zinc finger CCCH-type containing 7B
ZNF276 zinc finger protein 276
ZNF407 zinc finger protein 407
ZNF518A zinc finger protein 518A
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ACO1 aconitase 1, soluble
ADAM15 ADAM metallopeptidase domain 15
AOAH acyloxyacyl hydrolase (neutrophil)
AP4M1 adaptor-related protein complex 4, mu 1 subunit
APOLD1 apolipoprotein L domain containing 1
ASB13 ankyrin repeat and SOCS box containing 13
ASTE1 asteroid homolog 1 (Drosophila)
ATG9A autophagy related 9A
AXIN1 axin 1
C5AR1 complement component 5a receptor 1
C5ORF28 chromosome 5 open reading frame 28
C7ORF69 chromosome 7 open reading frame 69
CD9 CD9 molecule
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3
CINP cyclin-dependent kinase 2 interacting protein
CNKSR2 connector enhancer of kinase suppressor of Ras 2
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
DENND5B DENN/MADD domain containing 5B
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DOCK4 dedicator of cytokinesis 4
DPY19L2P2 DPY19L2 pseudogene 2
DYM dymeclin
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EPHB6 EPH receptor B6
FAM204A family with sequence similarity 204, member A
FES FES proto-oncogene, tyrosine kinase
FIP1L1 factor interacting with PAPOLA and CPSF1
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GPRC5C G protein-coupled receptor, class C, group 5, member C
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa
HLA-DMB major histocompatibility complex, class II, DM beta
IRAK4 interleukin-1 receptor-associated kinase 4
JMJD4 jumonji domain containing 4
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KIF13B kinesin family member 13B
KIF17 kinesin family member 17
KLHL36 kelch-like family member 36
LINC00260 long intergenic non-protein coding RNA 260
LNPEP leucyl/cystinyl aminopeptidase
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LY6E lymphocyte antigen 6 complex, locus E
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MAP3K8 mitogen-activated protein kinase kinase kinase 8
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
METTL16 methyltransferase like 16
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
MICALL2 MICAL-like 2
MSANTD2 Myb/SANT-like DNA-binding domain containing 2
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NCKAP1L NCK-associated protein 1-like
OXR1 oxidation resistance 1
PDLIM2 PDZ and LIM domain 2 (mystique)
PGP phosphoglycolate phosphatase
PHC1 polyhomeotic homolog 1 (Drosophila)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLAG1 pleiomorphic adenoma gene 1
POM121L2 POM121 transmembrane nucleoporin-like 2
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PWAR5 Prader Willi/Angelman region RNA 5
RARS arginyl-tRNA synthetase
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RFPL1S RFPL1 antisense RNA 1
RIN1 Ras and Rab interactor 1
RNF25 ring finger protein 25
RPAP2 RNA polymerase II associated protein 2
SCAI suppressor of cancer cell invasion
SERGEF secretion regulating guanine nucleotide exchange factor
SF3A3 splicing factor 3a, subunit 3, 60kDa
SKI SKI proto-oncogene
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SPAG4 sperm associated antigen 4
SPINT1 serine peptidase inhibitor, Kunitz type 1
SPRYD7 SPRY domain containing 7
SRD5A3 steroid 5 alpha-reductase 3
STK25 serine/threonine kinase 25
STX4 syntaxin 4
TAOK1 TAO kinase 1
TCTA T-cell leukemia translocation altered
TESK1 testis-specific kinase 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM159 transmembrane protein 159
TNNT1 troponin T type 1 (skeletal, slow)
TNRC6B trinucleotide repeat containing 6B
TUBGCP5 tubulin, gamma complex associated protein 5
VCPKMT valosin containing protein lysine (K) methyltransferase
ZNF329 zinc finger protein 329
ZNF428 zinc finger protein 428
ZNF468 zinc finger protein 468
ZNF665 zinc finger protein 665
ZNF747 zinc finger protein 747
ZNF76 zinc finger protein 76