eucatropine-3759 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the eucatropine-3759 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ACOT11 acyl-CoA thioesterase 11
AKAP4 A kinase (PRKA) anchor protein 4
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
ASIP agouti signaling protein
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
BBC3 BCL2 binding component 3
BMP10 bone morphogenetic protein 10
BRSK2 BR serine/threonine kinase 2
C9ORF16 chromosome 9 open reading frame 16
CA5B carbonic anhydrase VB, mitochondrial
CAMKV CaM kinase-like vesicle-associated
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CD40 CD40 molecule, TNF receptor superfamily member 5
CD79A CD79a molecule, immunoglobulin-associated alpha
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CLCN6 chloride channel, voltage-sensitive 6
CNKSR2 connector enhancer of kinase suppressor of Ras 2
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DAPK1 death-associated protein kinase 1
DICER1 dicer 1, ribonuclease type III
EPYC epiphycan
FAM212B family with sequence similarity 212, member B
FASLG Fas ligand (TNF superfamily, member 6)
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
GHRH growth hormone releasing hormone
GOLGA8A golgin A8 family, member A
GRIA3 glutamate receptor, ionotropic, AMPA 3
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRM2 glutamate receptor, metabotropic 2
GRM3 glutamate receptor, metabotropic 3
GSDMB gasdermin B
GTPBP1 GTP binding protein 1
HIST1H3A histone cluster 1, H3a
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HSPB6 heat shock protein, alpha-crystallin-related, B6
IFT27 intraflagellar transport 27
IGKV1D-13 immunoglobulin kappa variable 1D-13
IL1R1 interleukin 1 receptor, type I
INE1 inactivation escape 1 (non-protein coding)
ING4 inhibitor of growth family, member 4
JAG1 jagged 1
KCNA4 potassium channel, voltage gated shaker related subfamily A, member 4
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KIF1C kinesin family member 1C
KLHL25 kelch-like family member 25
KLK12 kallikrein-related peptidase 12
KMT2A lysine (K)-specific methyltransferase 2A
MIER2 mesoderm induction early response 1, family member 2
MXD4 MAX dimerization protein 4
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle
NDRG2 NDRG family member 2
NMT2 N-myristoyltransferase 2
NRG2 neuregulin 2
NRXN1 neurexin 1
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
NUMA1 nuclear mitotic apparatus protein 1
OLIG2 oligodendrocyte lineage transcription factor 2
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
PART1 prostate androgen-regulated transcript 1 (non-protein coding)
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PDE10A phosphodiesterase 10A
PDE2A phosphodiesterase 2A, cGMP-stimulated
PDLIM4 PDZ and LIM domain 4
PDPN podoplanin
PDZD3 PDZ domain containing 3
PF4 platelet factor 4
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PGAP3 post-GPI attachment to proteins 3
POSTN periostin, osteoblast specific factor
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRO2964 uncharacterized protein PRO2964
PRTN3 proteinase 3
PTPRH protein tyrosine phosphatase, receptor type, H
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RHBDD3 rhomboid domain containing 3
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SEZ6L seizure related 6 homolog (mouse)-like
SHOX2 short stature homeobox 2
SLC17A2 solute carrier family 17, member 2
SPAG8 sperm associated antigen 8
STK24 serine/threonine kinase 24
SYNDIG1 synapse differentiation inducing 1
TBCD tubulin folding cofactor D
TBX21 T-box 21
TFDP3 transcription factor Dp family, member 3
TG thyroglobulin
TGM4 transglutaminase 4
TRA T cell receptor alpha locus
TSSK2 testis-specific serine kinase 2
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VAMP5 vesicle-associated membrane protein 5
ZFP64 ZFP64 zinc finger protein

decreased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
APOL6 apolipoprotein L, 6
ARHGAP22 Rho GTPase activating protein 22
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARMC4 armadillo repeat containing 4
ATAD5 ATPase family, AAA domain containing 5
BCAS4 breast carcinoma amplified sequence 4
C1ORF35 chromosome 1 open reading frame 35
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CD79B CD79b molecule, immunoglobulin-associated beta
CDK9 cyclin-dependent kinase 9
CDKL3 cyclin-dependent kinase-like 3
CFAP44 cilia and flagella associated protein 44
CPNE7 copine VII
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DCAF4 DDB1 and CUL4 associated factor 4
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
EFNB1 ephrin-B1
EGR2 early growth response 2
ETV6 ets variant 6
FAM204A family with sequence similarity 204, member A
FBXL15 F-box and leucine-rich repeat protein 15
FBXL7 F-box and leucine-rich repeat protein 7
FGL1 fibrinogen-like 1
FMO4 flavin containing monooxygenase 4
FMOD fibromodulin
GAS8 growth arrest-specific 8
GPRASP1 G protein-coupled receptor associated sorting protein 1
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H2BM histone cluster 1, H2bm
HIST1H4D histone cluster 1, H4d
INO80D INO80 complex subunit D
IREB2 iron-responsive element binding protein 2
ITPKA inositol-trisphosphate 3-kinase A
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIAA1107 KIAA1107
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LINC00472 long intergenic non-protein coding RNA 472
LOC100127972 uncharacterized LOC100127972
LPAR3 lysophosphatidic acid receptor 3
MAGEH1 melanoma antigen family H1
MAPK3 mitogen-activated protein kinase 3
MATN3 matrilin 3
MED9 mediator complex subunit 9
MX1 MX dynamin-like GTPase 1
NAT6 N-acetyltransferase 6 (GCN5-related)
NEO1 neogenin 1
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
OSMR oncostatin M receptor
PDK4 pyruvate dehydrogenase kinase, isozyme 4
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
POM121 POM121 transmembrane nucleoporin
POMT2 protein-O-mannosyltransferase 2
POU2F1 POU class 2 homeobox 1
PPP6R1 protein phosphatase 6, regulatory subunit 1
PRPH peripherin
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
QPCTL glutaminyl-peptide cyclotransferase-like
QSER1 glutamine and serine rich 1
RNF122 ring finger protein 122
RPGRIP1L RPGRIP1-like
SAYSD1 SAYSVFN motif domain containing 1
SCEL sciellin
SCG2 secretogranin II
SCGB2A2 secretoglobin, family 2A, member 2
SCIN scinderin
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1
SETD1A SET domain containing 1A
SETD8 SET domain containing (lysine methyltransferase) 8
SGK2 serum/glucocorticoid regulated kinase 2
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SLC46A3 solute carrier family 46, member 3
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SLITRK5 SLIT and NTRK-like family, member 5
SNHG3 small nucleolar RNA host gene 3
STRN striatin, calmodulin binding protein
TAOK1 TAO kinase 1
TBX19 T-box 19
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TGFBI transforming growth factor, beta-induced, 68kDa
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TSC22D4 TSC22 domain family, member 4
TSPAN32 tetraspanin 32
TTC30A tetratricopeptide repeat domain 30A
TUBA4B tubulin, alpha 4b
UBQLN4 ubiquilin 4
VLDLR very low density lipoprotein receptor
WDR33 WD repeat domain 33
ZBTB48 zinc finger and BTB domain containing 48