eucatropine-3935 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the eucatropine-3935 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTL8 actin-like 8
ADGRE3 adhesion G protein-coupled receptor E3
ADORA3 adenosine A3 receptor
ART1 ADP-ribosyltransferase 1
BEST1 bestrophin 1
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CADM4 cell adhesion molecule 4
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CARD14 caspase recruitment domain family, member 14
CD177 CD177 molecule
CD209 CD209 molecule
CD7 CD7 molecule
CDC25C cell division cycle 25C
CDK14 cyclin-dependent kinase 14
CDK19 cyclin-dependent kinase 19
CNR1 cannabinoid receptor 1 (brain)
CRYGD crystallin, gamma D
DGAT1 diacylglycerol O-acyltransferase 1
DHRS12 dehydrogenase/reductase (SDR family) member 12
EDA ectodysplasin A
ELN elastin
EPYC epiphycan
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
FAIM2 Fas apoptotic inhibitory molecule 2
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FGF16 fibroblast growth factor 16
FGF21 fibroblast growth factor 21
FGFBP1 fibroblast growth factor binding protein 1
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
GAS7 growth arrest-specific 7
GEMIN7 gem (nuclear organelle) associated protein 7
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GRAP GRB2-related adaptor protein
HAND1 heart and neural crest derivatives expressed 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IRS4 insulin receptor substrate 4
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KLHL1 kelch-like family member 1
KLK8 kallikrein-related peptidase 8
LGALS8 lectin, galactoside-binding, soluble, 8
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LIME1 Lck interacting transmembrane adaptor 1
LINC00652 long intergenic non-protein coding RNA 652
LOX lysyl oxidase
LPAR1 lysophosphatidic acid receptor 1
LRRC48 leucine rich repeat containing 48
LUZP4 leucine zipper protein 4
MAPRE2 microtubule-associated protein, RP/EB family, member 2
MC5R melanocortin 5 receptor
MCAM melanoma cell adhesion molecule
MLNR motilin receptor
MORN1 MORN repeat containing 1
MYH15 myosin, heavy chain 15
NDN necdin, melanoma antigen (MAGE) family member
NOX1 NADPH oxidase 1
NYNRIN NYN domain and retroviral integrase containing
ORAI2 ORAI calcium release-activated calcium modulator 2
OXCT2 3-oxoacid CoA transferase 2
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PART1 prostate androgen-regulated transcript 1 (non-protein coding)
PCBP3 poly(rC) binding protein 3
PCDHB6 protocadherin beta 6
PDE4B phosphodiesterase 4B, cAMP-specific
PDGFB platelet-derived growth factor beta polypeptide
PGK2 phosphoglycerate kinase 2
PHF20L1 PHD finger protein 20-like 1
PKNOX1 PBX/knotted 1 homeobox 1
PLD1 phospholipase D1, phosphatidylcholine-specific
PRX periaxin
PTRF polymerase I and transcript release factor
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RASSF4 Ras association (RalGDS/AF-6) domain family member 4
RIMBP2 RIMS binding protein 2
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RND1 Rho family GTPase 1
RPS4Y1 ribosomal protein S4, Y-linked 1
SFRP4 secreted frizzled-related protein 4
SIRT4 sirtuin 4
STAT2 signal transducer and activator of transcription 2, 113kDa
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TAS2R3 taste receptor, type 2, member 3
TBX1 T-box 1
TDO2 tryptophan 2,3-dioxygenase
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TSPAN32 tetraspanin 32
UBQLN3 ubiquilin 3
UGT8 UDP glycosyltransferase 8
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
VNN2 vanin 2
VWA5A von Willebrand factor A domain containing 5A
ZNF175 zinc finger protein 175
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACSBG2 acyl-CoA synthetase bubblegum family member 2
ADAMTSL3 ADAMTS-like 3
ADTRP androgen-dependent TFPI-regulating protein
APLP1 amyloid beta (A4) precursor-like protein 1
BLNK B-cell linker
BMP15 bone morphogenetic protein 15
CAMK4 calcium/calmodulin-dependent protein kinase IV
CCNK cyclin K
CD82 CD82 molecule
CDHR2 cadherin-related family member 2
CDK18 cyclin-dependent kinase 18
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CEND1 cell cycle exit and neuronal differentiation 1
CHML choroideremia-like (Rab escort protein 2)
CIDEB cell death-inducing DFFA-like effector b
CLCN6 chloride channel, voltage-sensitive 6
CNTFR ciliary neurotrophic factor receptor
CPA4 carboxypeptidase A4
CRIP1 cysteine-rich protein 1 (intestinal)
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DCBLD2 discoidin, CUB and LCCL domain containing 2
DEAF1 DEAF1 transcription factor
DLL3 delta-like 3 (Drosophila)
DYSF dysferlin
EDN1 endothelin 1
EPHX2 epoxide hydrolase 2, cytoplasmic
ERN1 endoplasmic reticulum to nucleus signaling 1
ERN2 endoplasmic reticulum to nucleus signaling 2
EVPL envoplakin
F3 coagulation factor III (thromboplastin, tissue factor)
FFAR2 free fatty acid receptor 2
FKBP10 FK506 binding protein 10, 65 kDa
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPR143 G protein-coupled receptor 143
GPR27 G protein-coupled receptor 27
HIST1H4F histone cluster 1, H4f
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
HSF2BP heat shock transcription factor 2 binding protein
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
IFNA17 interferon, alpha 17
IL2RG interleukin 2 receptor, gamma
INCENP inner centromere protein antigens 135/155kDa
IQSEC2 IQ motif and Sec7 domain 2
ITGA8 integrin, alpha 8
KCNK5 potassium channel, two pore domain subfamily K, member 5
KCTD20 potassium channel tetramerization domain containing 20
KDM8 lysine (K)-specific demethylase 8
KREMEN2 kringle containing transmembrane protein 2
MBTPS2 membrane-bound transcription factor peptidase, site 2
MDM4 MDM4, p53 regulator
MFAP2 microfibrillar-associated protein 2
MRPS18C mitochondrial ribosomal protein S18C
MTA2 metastasis associated 1 family, member 2
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOTCH4 notch 4
NPFFR1 neuropeptide FF receptor 1
NPTX1 neuronal pentraxin I
PADI1 peptidyl arginine deiminase, type I
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLAC4 placenta-specific 4
PRKCE protein kinase C, epsilon
PSG4 pregnancy specific beta-1-glycoprotein 4
RAB30 RAB30, member RAS oncogene family
RAB40AL RAB40A, member RAS oncogene family-like
RAB40C RAB40C, member RAS oncogene family
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RHBDD3 rhomboid domain containing 3
RNF126P1 ring finger protein 126 pseudogene 1
RNF2 ring finger protein 2
RPL10L ribosomal protein L10-like
S100A9 S100 calcium binding protein A9
SENP7 SUMO1/sentrin specific peptidase 7
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SLC12A8 solute carrier family 12, member 8
SLC16A4 solute carrier family 16, member 4
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SNTA1 syntrophin, alpha 1
STK16 serine/threonine kinase 16
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TESC tescalcin
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TMEM45A transmembrane protein 45A
TRIM25 tripartite motif containing 25
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TTLL1 tubulin tyrosine ligase-like family member 1
UBTD1 ubiquitin domain containing 1
VIM vimentin
VPS9D1 VPS9 domain containing 1
XDH xanthine dehydrogenase
ZBTB33 zinc finger and BTB domain containing 33
ZIC3 Zic family member 3
ZNF532 zinc finger protein 532
ZNF862 zinc finger protein 862
ZSWIM1 zinc finger, SWIM-type containing 1