eucatropine-4316 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the eucatropine-4316 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABI2 abl-interactor 2
AIRE autoimmune regulator
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALOXE3 arachidonate lipoxygenase 3
ARID4B AT rich interactive domain 4B (RBP1-like)
ATAT1 alpha tubulin acetyltransferase 1
BCL2L1 BCL2-like 1
BMPR1B bone morphogenetic protein receptor, type IB
BTBD18 BTB (POZ) domain containing 18
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CAMK4 calcium/calmodulin-dependent protein kinase IV
CCR4 chemokine (C-C motif) receptor 4
CDRT1 CMT1A duplicated region transcript 1
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CFAP69 cilia and flagella associated protein 69
COL6A1 collagen, type VI, alpha 1
CORO7 coronin 7
CRLF1 cytokine receptor-like factor 1
CRTC1 CREB regulated transcription coactivator 1
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CYBB cytochrome b-245, beta polypeptide
DAAM2 dishevelled associated activator of morphogenesis 2
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DEPDC5 DEP domain containing 5
DGCR2 DiGeorge syndrome critical region gene 2
DGCR8 DGCR8 microprocessor complex subunit
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DTNA dystrobrevin, alpha
EFNB3 ephrin-B3
EGFL7 EGF-like-domain, multiple 7
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GGT1 gamma-glutamyltransferase 1
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GRM7 glutamate receptor, metabotropic 7
GTPBP1 GTP binding protein 1
HIP1 huntingtin interacting protein 1
HSPG2 heparan sulfate proteoglycan 2
IL32 interleukin 32
INO80B INO80 complex subunit B
INO80D INO80 complex subunit D
JAK3 Janus kinase 3
KDM4B lysine (K)-specific demethylase 4B
KREMEN2 kringle containing transmembrane protein 2
LGALS8 lectin, galactoside-binding, soluble, 8
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
MAN1C1 mannosidase, alpha, class 1C, member 1
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MARK2 MAP/microtubule affinity-regulating kinase 2
MNMIP1 manchette microtubule inner protein 1
MOBP myelin-associated oligodendrocyte basic protein
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUC4 mucin 4, cell surface associated
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NKX2-5 NK2 homeobox 5
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
NUMA1 nuclear mitotic apparatus protein 1
OR7A17 olfactory receptor, family 7, subfamily A, member 17
PASK PAS domain containing serine/threonine kinase
PBX1 pre-B-cell leukemia homeobox 1
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDH11X protocadherin 11 X-linked
PKNOX2 PBX/knotted 1 homeobox 2
PLCL2 phospholipase C-like 2
POU2F2 POU class 2 homeobox 2
POU2F3 POU class 2 homeobox 3
PRB3 proline-rich protein BstNI subfamily 3
RASL11B RAS-like, family 11, member B
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
REST RE1-silencing transcription factor
RFX2 regulatory factor X, 2 (influences HLA class II expression)
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
RPS28 ribosomal protein S28
RRH retinal pigment epithelium-derived rhodopsin homolog
SELL selectin L
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SH3BP2 SH3-domain binding protein 2
SH3PXD2A SH3 and PX domains 2A
SLC13A1 solute carrier family 13 (sodium/sulfate symporter), member 1
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC48A1 solute carrier family 48 (heme transporter), member 1
SMO smoothened, frizzled class receptor
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SOX21 SRY (sex determining region Y)-box 21
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRRT serrate, RNA effector molecule
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae)
SYCE1L synaptonemal complex central element protein 1-like
SYT17 synaptotagmin XVII
TIMP3 TIMP metallopeptidase inhibitor 3
TMEM259 transmembrane protein 259
TNS1 tensin 1
TP53I11 tumor protein p53 inducible protein 11
U2AF2 U2 small nuclear RNA auxiliary factor 2
WIZ widely interspaced zinc finger motifs
ZMYND10 zinc finger, MYND-type containing 10
ZNF214 zinc finger protein 214
ZNF639 zinc finger protein 639

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ADRBK2 adrenergic, beta, receptor kinase 2
ATG10 autophagy related 10
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C11ORF30 chromosome 11 open reading frame 30
C14ORF79 chromosome 14 open reading frame 79
C16ORF62 chromosome 16 open reading frame 62
C1ORF54 chromosome 1 open reading frame 54
CD101 CD101 molecule
CD53 CD53 molecule
CENPO centromere protein O
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CLCN6 chloride channel, voltage-sensitive 6
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CNTN1 contactin 1
COL21A1 collagen, type XXI, alpha 1
DBF4B DBF4 zinc finger B
DOK5 docking protein 5
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EDIL3 EGF-like repeats and discoidin I-like domains 3
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
FLCN folliculin
FMOD fibromodulin
FOXC1 forkhead box C1
FZD10 frizzled class receptor 10
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GLB1L galactosidase, beta 1-like
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H3C histone cluster 1, H3c
HOXA2 homeobox A2
HOXB2 homeobox B2
HOXC10 homeobox C10
HOXC5 homeobox C5
IDI2-AS1 IDI2 antisense RNA 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFNA14 interferon, alpha 14
IKZF5 IKAROS family zinc finger 5 (Pegasus)
ITK IL2-inducible T-cell kinase
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KRT6B keratin 6B, type II
LOC257152 uncharacterized LOC257152
LRRC37A3 leucine rich repeat containing 37, member A3
LRRK1 leucine-rich repeat kinase 1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAGEA6 melanoma antigen family A6
MAGEH1 melanoma antigen family H1
MANEA mannosidase, endo-alpha
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MED31 mediator complex subunit 31
MICALL2 MICAL-like 2
MYOZ3 myozenin 3
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NID2 nidogen 2 (osteonidogen)
NSUN6 NOP2/Sun domain family, member 6
NUPL2 nucleoporin like 2
ODF2 outer dense fiber of sperm tails 2
OSBP2 oxysterol binding protein 2
PCDHGB5 protocadherin gamma subfamily B, 5
POLL polymerase (DNA directed), lambda
POM121L2 POM121 transmembrane nucleoporin-like 2
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRR15L proline rich 15-like
PRSS53 protease, serine, 53
QSER1 glutamine and serine rich 1
RAB23 RAB23, member RAS oncogene family
RNF39 ring finger protein 39
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
S100A3 S100 calcium binding protein A3
SERGEF secretion regulating guanine nucleotide exchange factor
SGPP1 sphingosine-1-phosphate phosphatase 1
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC25A40 solute carrier family 25, member 40
SMAD5 SMAD family member 5
STARD5 StAR-related lipid transfer (START) domain containing 5
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TEP1 telomerase-associated protein 1
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TTLL7 tubulin tyrosine ligase-like family member 7
TWISTNB TWIST neighbor
UBTD1 ubiquitin domain containing 1
UNKL unkempt family zinc finger-like
VN1R1 vomeronasal 1 receptor 1
WDR25 WD repeat domain 25
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
ZNF225 zinc finger protein 225
ZNF253 zinc finger protein 253
ZNF571 zinc finger protein 571
ZNF652 zinc finger protein 652
ZNF711 zinc finger protein 711
ZNF74 zinc finger protein 74
ZNF76 zinc finger protein 76
ZNF767P zinc finger family member 767, pseudogene
ZNF770 zinc finger protein 770