excessive Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

262 genes co-occuring with the biological term excessive in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABAT 4-aminobutyrate aminotransferase
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11
ACKR2 atypical chemokine receptor 2
ACLY ATP citrate lyase
ADA adenosine deaminase
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
ADIPOQ adiponectin, C1Q and collagen domain containing
ADRB1 adrenoceptor beta 1
ADRB2 adrenoceptor beta 2, surface
ADRB3 adrenoceptor beta 3
AGER advanced glycosylation end product-specific receptor
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALOX5 arachidonate 5-lipoxygenase
AMH anti-Mullerian hormone
ANGPT1 angiopoietin 1
ANGPT2 angiopoietin 2
APP amyloid beta (A4) precursor protein
AR androgen receptor
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATM ATM serine/threonine kinase
AURKA aurora kinase A
BCL2 B-cell CLL/lymphoma 2
BDNF brain-derived neurotrophic factor
BMI1 BMI1 proto-oncogene, polycomb ring finger
BRCA1 breast cancer 1, early onset
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
C4BPA complement component 4 binding protein, alpha
C5 complement component 5
C7 complement component 7
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CAPN2 calpain 2, (m/II) large subunit
CARD8 caspase recruitment domain family, member 8
CASR calcium-sensing receptor
CAT catalase
CCK cholecystokinin
CCND1 cyclin D1
CCND2 cyclin D2
CCND3 cyclin D3
CD151 CD151 molecule (Raph blood group)
CDH13 cadherin 13
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CENPJ centromere protein J
CEP120 centrosomal protein 120kDa
CFH complement factor H
CFL1 cofilin 1 (non-muscle)
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CNR2 cannabinoid receptor 2 (macrophage)
COL1A1 collagen, type I, alpha 1
COMT catechol-O-methyltransferase
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa
CRHR1 corticotropin releasing hormone receptor 1
CRP C-reactive protein, pentraxin-related
CTSB cathepsin B
CUL1 cullin 1
CXCL8 chemokine (C-X-C motif) ligand 8
CYBA cytochrome b-245, alpha polypeptide
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYSLTR2 cysteinyl leukotriene receptor 2
DDIT3 DNA-damage-inducible transcript 3
DES desmin
DIO2 deiodinase, iodothyronine, type II
DIO3 deiodinase, iodothyronine, type III
DISC1 disrupted in schizophrenia 1
DPP4 dipeptidyl-peptidase 4
E2F1 E2F transcription factor 1
EGFR epidermal growth factor receptor
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
ELANE elastase, neutrophil expressed
EP300 E1A binding protein p300
EPO erythropoietin
ERO1L ERO1-like (S. cerevisiae)
F12 coagulation factor XII (Hageman factor)
F13A1 coagulation factor XIII, A1 polypeptide
F2 coagulation factor II (thrombin)
F2RL1 coagulation factor II (thrombin) receptor-like 1
F3 coagulation factor III (thromboplastin, tissue factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FBXO18 F-box protein, helicase, 18
FCRL3 Fc receptor-like 3
FES FES proto-oncogene, tyrosine kinase
FGF2 fibroblast growth factor 2 (basic)
FGF23 fibroblast growth factor 23
FGFR1OP2 FGFR1 oncogene partner 2
FGFR3 fibroblast growth factor receptor 3
FLT1 fms-related tyrosine kinase 1
FLT3 fms-related tyrosine kinase 3
FOSL1 FOS-like antigen 1
FOXO1 forkhead box O1
GADD45A growth arrest and DNA-damage-inducible, alpha
GJB2 gap junction protein, beta 2, 26kDa
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GOT1 glutamic-oxaloacetic transaminase 1, soluble
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GPX7 glutathione peroxidase 7
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HAMP hepcidin antimicrobial peptide
HBB hemoglobin, beta
HDAC9 histone deacetylase 9
HFE hemochromatosis
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMGB1 high mobility group box 1
HMOX1 heme oxygenase 1
HSF1 heat shock transcription factor 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IDO1 indoleamine 2,3-dioxygenase 1
IFIH1 interferon induced with helicase C domain 1
IFNA1 interferon, alpha 1
IFNB1 interferon, beta 1, fibroblast
IGF1R insulin-like growth factor 1 receptor
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP4 insulin-like growth factor binding protein 4
IHH indian hedgehog
IL10 interleukin 10
IL17A interleukin 17A
IL18 interleukin 18
IL2 interleukin 2
IL22 interleukin 22
IL2RA interleukin 2 receptor, alpha
IL6 interleukin 6
INHBA inhibin, beta A
INHBB inhibin, beta B
IRF8 interferon regulatory factor 8
IRS1 insulin receptor substrate 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGB1BP1 integrin beta 1 binding protein 1
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KMT2A lysine (K)-specific methyltransferase 2A
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT18 keratin 18, type I
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
LCN2 lipocalin 2
LDLRAD4 low density lipoprotein receptor class A domain containing 4
LEP leptin
LEPR leptin receptor
LHCGR luteinizing hormone/choriogonadotropin receptor
LOX lysyl oxidase
LTB4R leukotriene B4 receptor
MAOA monoamine oxidase A
MAPK14 mitogen-activated protein kinase 14
MAPK8 mitogen-activated protein kinase 8
MET MET proto-oncogene, receptor tyrosine kinase
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR146A microRNA 146a
MIR155 microRNA 155
MIR449A microRNA 449a
MIR449B microRNA 449b
MIR9-1 microRNA 9-1
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MPZ myelin protein zero
MSX1 msh homeobox 1
MTTP microsomal triglyceride transfer protein
MUC1 mucin 1, cell surface associated
MUS81 MUS81 structure-specific endonuclease subunit
MYD88 myeloid differentiation primary response 88
MYLK myosin light chain kinase
NAMPT nicotinamide phosphoribosyltransferase
NDEL1 nudE neurodevelopment protein 1-like 1
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NF1 neurofibromin 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NLRP3 NLR family, pyrin domain containing 3
NME1 NME/NM23 nucleoside diphosphate kinase 1
NOTCH1 notch 1
NPC1L1 NPC1-like 1
NPPA natriuretic peptide A
NPR2 natriuretic peptide receptor 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NUCB2 nucleobindin 2
OGG1 8-oxoguanine DNA glycosylase
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
ORM1 orosomucoid 1
OTUD7B OTU deubiquitinase 7B
PCNA proliferating cell nuclear antigen
PDCD1 programmed cell death 1
PI3 peptidase inhibitor 3, skin-derived
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PLAUR plasminogen activator, urokinase receptor
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLK4 polo-like kinase 4
POSTN periostin, osteoblast specific factor
PPARG peroxisome proliferator-activated receptor gamma
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRSS8 protease, serine, 8
PSEN1 presenilin 1
PTGIS prostaglandin I2 (prostacyclin) synthase
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH parathyroid hormone
PTX3 pentraxin 3, long
PYGL phosphorylase, glycogen, liver
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RC3H1 ring finger and CCCH-type domains 1
RHO rhodopsin
RHOA ras homolog family member A
RXRA retinoid X receptor, alpha
S100A12 S100 calcium binding protein A12
S100A9 S100 calcium binding protein A9
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SESN3 sestrin 3
SF3B1 splicing factor 3b, subunit 1, 155kDa
SFTPD surfactant protein D
SGK1 serum/glucocorticoid regulated kinase 1
SH3GL1 SH3-domain GRB2-like 1
SIRT1 sirtuin 1
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLPI secretory leukocyte peptidase inhibitor
SMAD7 SMAD family member 7
SOD1 superoxide dismutase 1, soluble
SPICE1 spindle and centriole associated protein 1
SQSTM1 sequestosome 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
SUFU suppressor of fused homolog (Drosophila)
SUMO4 small ubiquitin-like modifier 4
SYT11 synaptotagmin XI
TAC1 tachykinin, precursor 1
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TERT telomerase reverse transcriptase
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFB1 transforming growth factor, beta 1
TGFB3 transforming growth factor, beta 3
THBD thrombomodulin
TIMP1 TIMP metallopeptidase inhibitor 1
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR5 toll-like receptor 5
TLR9 toll-like receptor 9
TMPRSS6 transmembrane protease, serine 6
TNF tumor necrosis factor
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNPO3 transportin 3
TP53 tumor protein p53
TRPM7 transient receptor potential cation channel, subfamily M, member 7
TRPS1 trichorhinophalangeal syndrome I
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TTC5 tetratricopeptide repeat domain 5
UBXN1 UBX domain protein 1
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UIMC1 ubiquitin interaction motif containing 1
VCAN versican
VCP valosin containing protein
VEGFA vascular endothelial growth factor A
VMA21 VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
WNT4 wingless-type MMTV integration site family, member 4
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1