excitatory synapse Gene Set

Dataset GO Cellular Component Annotations 2025
Category structural or functional annotations
Type cellular component
Description A synapse in which an action potential in the presynaptic cell increases the probability of an action potential occurring in the postsynaptic cell. (Gene Ontology, GO_0060076)
External Link http://amigo.geneontology.org/amigo/term/GO:0060076
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Genes

25 proteins localized to the excitatory synapse cellular component from the curated GO Cellular Component Annotations 2025 dataset.

Symbol Name
ADCY8 adenylate cyclase 8 (brain)
AKAP5 A kinase (PRKA) anchor protein 5
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3
BSN bassoon presynaptic cytomatrix protein
ELFN1 extracellular leucine-rich repeat and fibronectin type III domain containing 1
FGFR2 fibroblast growth factor receptor 2
GPRIN1 G protein regulated inducer of neurite outgrowth 1
GRIA2 glutamate receptor, ionotropic, AMPA 2
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
LLGL1 lethal giant larvae homolog 1 (Drosophila)
NETO1 neuropilin (NRP) and tolloid (TLL)-like 1
NLGN1 neuroligin 1
NLGN3 neuroligin 3
NLGN4X neuroligin 4, X-linked
NLGN4Y neuroligin 4, Y-linked
PALLD palladin, cytoskeletal associated protein
SHANK1 SH3 and multiple ankyrin repeat domains 1
SHISA6 shisa family member 6
SHISA7 shisa family member 7
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC17A8 solute carrier family 17 (vesicular glutamate transporter), member 8
SRPX2 sushi-repeat containing protein, X-linked 2
SYNDIG1 synapse differentiation inducing 1
SYT12 synaptotagmin XII