| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the exemestane-165 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACOT8 | acyl-CoA thioesterase 8 |
| ACOX1 | acyl-CoA oxidase 1, palmitoyl |
| ACSL6 | acyl-CoA synthetase long-chain family member 6 |
| ADAMTSL4 | ADAMTS-like 4 |
| AGRP | agouti related neuropeptide |
| AQP2 | aquaporin 2 (collecting duct) |
| ATF6 | activating transcription factor 6 |
| ATP10B | ATPase, class V, type 10B |
| B9D1 | B9 protein domain 1 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| C1ORF61 | chromosome 1 open reading frame 61 |
| CCZ1 | CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae) |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CFAP70 | cilia and flagella associated protein 70 |
| CHST4 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 |
| CLCA1 | chloride channel accessory 1 |
| CLIC4 | chloride intracellular channel 4 |
| CNTFR | ciliary neurotrophic factor receptor |
| CNTN1 | contactin 1 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CRCP | CGRP receptor component |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| CYP3A43 | cytochrome P450, family 3, subfamily A, polypeptide 43 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DNAH3 | dynein, axonemal, heavy chain 3 |
| DOCK1 | dedicator of cytokinesis 1 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| DUS2 | dihydrouridine synthase 2 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| EGR4 | early growth response 4 |
| ETV1 | ets variant 1 |
| FAM153A | family with sequence similarity 153, member A |
| GANAB | glucosidase, alpha; neutral AB |
| GJB3 | gap junction protein, beta 3, 31kDa |
| GJD2 | gap junction protein, delta 2, 36kDa |
| GRB7 | growth factor receptor-bound protein 7 |
| GRM6 | glutamate receptor, metabotropic 6 |
| GRPR | gastrin-releasing peptide receptor |
| GSK3A | glycogen synthase kinase 3 alpha |
| HADH | hydroxyacyl-CoA dehydrogenase |
| HPS1 | Hermansky-Pudlak syndrome 1 |
| IGFLR1 | IGF-like family receptor 1 |
| KALRN | kalirin, RhoGEF kinase |
| KRT38 | keratin 38, type I |
| LMNA | lamin A/C |
| LOC647070 | uncharacterized LOC647070 |
| MAGED2 | melanoma antigen family D2 |
| MED9 | mediator complex subunit 9 |
| MPPED1 | metallophosphoesterase domain containing 1 |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NTAN1 | N-terminal asparagine amidase |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| NXPH3 | neurexophilin 3 |
| PALM | paralemmin |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) |
| PIN4 | peptidylprolyl cis/trans isomerase, NIMA-interacting 4 |
| PODXL | podocalyxin-like |
| PPM1F | protein phosphatase, Mg2+/Mn2+ dependent, 1F |
| PRDM11 | PR domain containing 11 |
| PRDM5 | PR domain containing 5 |
| PRDX2 | peroxiredoxin 2 |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha |
| PTCRA | pre T-cell antigen receptor alpha |
| RAB29 | RAB29, member RAS oncogene family |
| RASA1 | RAS p21 protein activator (GTPase activating protein) 1 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 |
| SCAMP1 | secretory carrier membrane protein 1 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SEMA6D | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D |
| SETD1B | SET domain containing 1B |
| SIGLEC6 | sialic acid binding Ig-like lectin 6 |
| SLC16A7 | solute carrier family 16 (monocarboxylate transporter), member 7 |
| SNAI2 | snail family zinc finger 2 |
| SON | SON DNA binding protein |
| SPG11 | spastic paraplegia 11 (autosomal recessive) |
| SPRR1A | small proline-rich protein 1A |
| SRCAP | Snf2-related CREBBP activator protein |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| SUGP2 | SURP and G patch domain containing 2 |
| SYF2 | SYF2 pre-mRNA-splicing factor |
| TAF6L | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TGS1 | trimethylguanosine synthase 1 |
| TLN1 | talin 1 |
| TMCC1 | transmembrane and coiled-coil domain family 1 |
| TMEM246 | transmembrane protein 246 |
| TMEM97 | transmembrane protein 97 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TRAF3 | TNF receptor-associated factor 3 |
| TUBA4B | tubulin, alpha 4b |
| UBQLN4 | ubiquilin 4 |
| WAS | Wiskott-Aldrich syndrome |
| WRAP53 | WD repeat containing, antisense to TP53 |
| YLPM1 | YLP motif containing 1 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZNF576 | zinc finger protein 576 |
| Symbol | Name |
|---|---|
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase |
| ADNP | activity-dependent neuroprotector homeobox |
| ANKRD40 | ankyrin repeat domain 40 |
| ATAD3A | ATPase family, AAA domain containing 3A |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| BBC3 | BCL2 binding component 3 |
| BRD1 | bromodomain containing 1 |
| C10ORF2 | chromosome 10 open reading frame 2 |
| C12ORF43 | chromosome 12 open reading frame 43 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| C9ORF78 | chromosome 9 open reading frame 78 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CCDC6 | coiled-coil domain containing 6 |
| CCDC64 | coiled-coil domain containing 64 |
| CCNL2 | cyclin L2 |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CHAF1B | chromatin assembly factor 1, subunit B (p60) |
| CIC | capicua transcriptional repressor |
| CLASP1 | cytoplasmic linker associated protein 1 |
| CLDN9 | claudin 9 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| COBL | cordon-bleu WH2 repeat protein |
| CROT | carnitine O-octanoyltransferase |
| CTDNEP1 | CTD nuclear envelope phosphatase 1 |
| DCLRE1A | DNA cross-link repair 1A |
| ENTPD6 | ectonucleoside triphosphate diphosphohydrolase 6 (putative) |
| EPPK1 | epiplakin 1 |
| ERCC6L | excision repair cross-complementation group 6-like |
| ERF | Ets2 repressor factor |
| EVL | Enah/Vasp-like |
| EXOSC9 | exosome component 9 |
| FOXD1 | forkhead box D1 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GMNN | geminin, DNA replication inhibitor |
| GTF3C3 | general transcription factor IIIC, polypeptide 3, 102kDa |
| HDAC7 | histone deacetylase 7 |
| HIST1H4J | histone cluster 1, H4j |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| KIAA0753 | KIAA0753 |
| KIAA1551 | KIAA1551 |
| KIAA1598 | |
| LMNB1 | lamin B1 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| LSR | lipolysis stimulated lipoprotein receptor |
| LTBR | lymphotoxin beta receptor (TNFR superfamily, member 3) |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MAPK3 | mitogen-activated protein kinase 3 |
| MARC1 | mitochondrial amidoxime reducing component 1 |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MMP17 | matrix metallopeptidase 17 (membrane-inserted) |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MSL1 | male-specific lethal 1 homolog (Drosophila) |
| MT1HL1 | metallothionein 1H-like 1 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MVD | mevalonate (diphospho) decarboxylase |
| MYLIP | myosin regulatory light chain interacting protein |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing |
| NARFL | nuclear prelamin A recognition factor-like |
| NT5C | 5', 3'-nucleotidase, cytosolic |
| NUP93 | nucleoporin 93kDa |
| PAK1IP1 | PAK1 interacting protein 1 |
| PELP1 | proline, glutamate and leucine rich protein 1 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
| PGM3 | phosphoglucomutase 3 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PMM2 | phosphomannomutase 2 |
| POLR1E | polymerase (RNA) I polypeptide E, 53kDa |
| RNF121 | ring finger protein 121 |
| RPS6KB2 | ribosomal protein S6 kinase, 70kDa, polypeptide 2 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SERINC5 | serine incorporator 5 |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 |
| SLC41A3 | solute carrier family 41, member 3 |
| SMYD5 | SMYD family member 5 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPON2 | spondin 2, extracellular matrix protein |
| SREBF1 | sterol regulatory element binding transcription factor 1 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 |
| TBCC | tubulin folding cofactor C |
| TCEA2 | transcription elongation factor A (SII), 2 |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 |
| TMEM159 | transmembrane protein 159 |
| TOLLIP | toll interacting protein |
| TRNAU1AP | tRNA selenocysteine 1 associated protein 1 |
| TSPYL2 | TSPY-like 2 |
| UBQLN2 | ubiquilin 2 |
| UIMC1 | ubiquitin interaction motif containing 1 |
| UNC13B | unc-13 homolog B (C. elegans) |
| UPK3B | uroplakin 3B |
| WDR13 | WD repeat domain 13 |
| WDR18 | WD repeat domain 18 |
| ZIC1 | Zic family member 1 |
| ZNF195 | zinc finger protein 195 |
| ZNF580 | zinc finger protein 580 |
