exemestane Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A 17-oxo steroid that is androsta-1,4-diene-3,17-dione in which the hydrogens at position 6 are replaced by a double bond to a methylene group. A selective inhibitor of the aromatase (oestrogen synthase) system, it is used in the treatment of advanced breast cancer. (Chemical Entities of Biological Interest Ontology, CHEBI_4953)
External Link http://ctdbase.org/detail.go?type=chem&acc=C056516
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Genes

5 genes/proteins interacting with the chemical exemestane from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
ESR1 estrogen receptor 1
MKI67 marker of proliferation Ki-67
PGR progesterone receptor
SLC22A2 solute carrier family 22 (organic cation transporter), member 2