| Dataset | Guide to Pharmacology Chemical Ligands of Receptors |
| Category | physical interactions |
| Type | ligand (chemical) |
| Description | A bioactive polypeptide of 39 amino acid residues isolated from the saliva of the Gila monster (Heloderma suspectum). High-affinity glucagon-like peptide 1 (GLP-1) receptor agonist (Kd = 136 pM); potently induces cAMP formation without stimulating amylase release in pancreatic acini; potentiates glucose-induced insulin secretion in isolated rat islets; protects against glutamate-induced neurotoxicity. A synthetic version is called exenatide. (Chemical Entities of Biological Interest Ontology, CHEBI_64073) |
| External Link | http://www.guidetopharmacology.org/GRAC/LigandDisplayForward?ligandId=1135 |
| Similar Terms | |
| Downloads & Tools |
1 receptors of the exendin-4 ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.
| Symbol | Name |
|---|---|
| GLP1R | glucagon-like peptide 1 receptor |
