exercise test Gene Set

Dataset GAD Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description Controlled physical activity, more strenuous than at rest, which is performed in order to allow assessment of physiological functions, particularly cardiovascular and pulmonary, but also aerobic capacity. Maximal (most intense) exercise is usually required but submaximal exercise is also used. The intensity of exercise is often graded, using criteria such as rate of work done, oxygen consumption, and heart rate. (Experimental Factor Ontology, EFO_0004328)
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Genes

68 genes associated with the disease exercise test in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

Symbol Name
ABHD5 abhydrolase domain containing 5
ADCY8 adenylate cyclase 8 (brain)
AFF3 AF4/FMR2 family, member 3
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
ARHGAP10 Rho GTPase activating protein 10
ARSB arylsulfatase B
ATG10 autophagy related 10
CDH10 cadherin 10, type 2 (T2-cadherin)
CDH18 cadherin 18, type 2
CDK8 cyclin-dependent kinase 8
CNGB3 cyclic nucleotide gated channel beta 3
CNTN4 contactin 4
CSMD1 CUB and Sushi multiple domains 1
CYYR1 cysteine/tyrosine-rich 1
DMD dystrophin
EBF2 early B-cell factor 2
EFNA5 ephrin-A5
EGFLAM EGF-like, fibronectin type III and laminin G domains
ELMO1 engulfment and cell motility 1
EPS8 epidermal growth factor receptor pathway substrate 8
FAF1 Fas (TNFRSF6) associated factor 1
FAM76A family with sequence similarity 76, member A
FLT1 fms-related tyrosine kinase 1
FMN2 formin 2
FRMPD4 FERM and PDZ domain containing 4
GJA5 gap junction protein, alpha 5, 40kDa
KCNIP4 Kv channel interacting protein 4
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
LAMA2 laminin, alpha 2
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
MDGA2 MAM domain containing glycosylphosphatidylinositol anchor 2
MIR99AHG mir-99a-let-7c cluster host gene
MSRB3 methionine sulfoxide reductase B3
NPAS3 neuronal PAS domain protein 3
OPCML opioid binding protein/cell adhesion molecule-like
PBLD phenazine biosynthesis-like protein domain containing
PCDH15 protocadherin-related 15
PDZRN4 PDZ domain containing ring finger 4
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PTPRQ protein tyrosine phosphatase, receptor type, Q
RARB retinoic acid receptor, beta
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RYR2 ryanodine receptor 2 (cardiac)
RYR3 ryanodine receptor 3
SCHIP1 schwannomin interacting protein 1
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SGCZ sarcoglycan, zeta
SHROOM4 shroom family member 4
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SPAG16 sperm associated antigen 16
SPINK14 serine peptidase inhibitor, Kazal type 14 (putative)
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SPRN shadow of prion protein homolog (zebrafish)
THSD7B thrombospondin, type I, domain containing 7B
TMEM131 transmembrane protein 131
TMEM244 transmembrane protein 244
TMOD2 tropomodulin 2 (neuronal)
TMOD3 tropomodulin 3 (ubiquitous)
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TSPAN5 tetraspanin 5
VAV3 vav 3 guanine nucleotide exchange factor
VPS13B vacuolar protein sorting 13 homolog B (yeast)
WIF1 WNT inhibitory factor 1
WRN Werner syndrome, RecQ helicase-like
ZC3H12C zinc finger CCCH-type containing 12C