exfoliation syndrome Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description OMIM mapping confirmed by DO. [SN]. (Human Disease Ontology, DOID_13641)
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Genes

89 genes co-occuring with the disease exfoliation syndrome in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
LOXL1 lysyl oxidase-like 1 3.02822
PEX19 peroxisomal biogenesis factor 19 2.00102
CCDC167 coiled-coil domain containing 167 1.35202
TBC1D21 TBC1 domain family, member 21 1.35202
FBN1 fibrillin 1 1.27606
LYST lysosomal trafficking regulator 1.25558
TMEM9 transmembrane protein 9 1.24298
CNTNAP2 contactin associated protein-like 2 1.20656
LOX lysyl oxidase 1.19834
MGST1 microsomal glutathione S-transferase 1 1.15368
STMN4 stathmin-like 4 1.13585
LTBP1 latent transforming growth factor beta binding protein 1 1.12783
B3GAT1 beta-1,3-glucuronyltransferase 1 1.04714
CTNNBL1 catenin, beta like 1 1.02102
FBLN2 fibulin 2 0.985585
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 0.953273
LTBP3 latent transforming growth factor beta binding protein 3 0.898282
LTBP2 latent transforming growth factor beta binding protein 2 0.858543
CLPTM1 cleft lip and palate associated transmembrane protein 1 0.852402
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase 0.84544
WDR36 WD repeat domain 36 0.840525
MFAP2 microfibrillar-associated protein 2 0.835198
EHD1 EH-domain containing 1 0.77575
TIMP2 TIMP metallopeptidase inhibitor 2 0.754934
MYOC myocilin, trabecular meshwork inducible glucocorticoid response 0.747204
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2 0.730976
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.730166
GGT2 gamma-glutamyltransferase 2 0.729357
PHGDH phosphoglycerate dehydrogenase 0.727333
ELN elastin 0.726524
TGFB2 transforming growth factor, beta 2 0.713601
KLK15 kallikrein-related peptidase 15 0.712796
OPTN optineurin 0.709169
USE1 unconventional SNARE in the ER 1 homolog (S. cerevisiae) 0.701526
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 0.680697
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.668742
SEBOX SEBOX homeobox 0.650113
SDC3 syndecan 3 0.649718
TYRP1 tyrosinase-related protein 1 0.612401
AKAP2 A kinase (PRKA) anchor protein 2 0.61162
TIMP1 TIMP metallopeptidase inhibitor 1 0.59991
CTGF connective tissue growth factor 0.589001
MMP2 matrix metallopeptidase 2 0.583552
MT-ATP8 ATP synthase F0 subunit 8 0.57655
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) 0.565666
LOXL2 lysyl oxidase-like 2 0.555568
PADI2 peptidyl arginine deiminase, type II 0.52536
TGFB1 transforming growth factor, beta 1 0.523045
GGT1 gamma-glutamyltransferase 1 0.505356
SIX6 SIX homeobox 6 0.496557
VCAN versican 0.494648
MMP1 matrix metallopeptidase 1 0.493122
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) 0.482844
DSC2 desmocollin 2 0.448064
MGAT4C MGAT4 family, member C 0.442418
GPNMB glycoprotein (transmembrane) nmb 0.431519
SZRD1 SUZ RNA binding domain containing 1 0.427765
GSTTP1 glutathione S-transferase theta pseudogene 1 0.390397
GSTT1 glutathione S-transferase theta 1 0.390025
CLU clusterin 0.356341
TIMP4 TIMP metallopeptidase inhibitor 4 0.332852
HPN hepsin 0.331025
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3 0.323002
SIX1 SIX homeobox 1 0.311739
MMP9 matrix metallopeptidase 9 0.304142
APOE apolipoprotein E 0.302337
SOD2 superoxide dismutase 2, mitochondrial 0.281153
NID1 nidogen 1 0.269753
FRZB frizzled-related protein 0.26514
EDN1 endothelin 1 0.261245
UBE2B ubiquitin-conjugating enzyme E2B 0.247852
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase 0.24715
LAMA3 laminin, alpha 3 0.242245
CAT catalase 0.235964
IL31RA interleukin 31 receptor A 0.229024
ADRA1D adrenoceptor alpha 1D 0.221108
FN1 fibronectin 1 0.20658
GHRL ghrelin/obestatin prepropeptide 0.205585
NFIC nuclear factor I/C (CCAAT-binding transcription factor) 0.195501
NFIX nuclear factor I/X (CCAAT-binding transcription factor) 0.1936
HPGDS hematopoietic prostaglandin D synthase 0.188326
GSTM1 glutathione S-transferase mu 1 0.187415
EEF2 eukaryotic translation elongation factor 2 0.183835
CELA1 chymotrypsin-like elastase family, member 1 0.177301
GLS glutaminase 0.175146
ALB albumin 0.172544
CELA3B chymotrypsin-like elastase family, member 3B 0.170299
UBE2A ubiquitin-conjugating enzyme E2A 0.164359
MMP3 matrix metallopeptidase 3 0.160387