| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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195 genes differentially expressed following the exisulind-314 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABLIM3 | actin binding LIM protein family, member 3 |
| ADAMTS2 | ADAM metallopeptidase with thrombospondin type 1 motif, 2 |
| ADD2 | adducin 2 (beta) |
| ADGRL3 | adhesion G protein-coupled receptor L3 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 |
| ANK1 | ankyrin 1, erythrocytic |
| ARSA | arylsulfatase A |
| ATP11A | ATPase, class VI, type 11A |
| BCL6 | B-cell CLL/lymphoma 6 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C19ORF66 | chromosome 19 open reading frame 66 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CA11 | carbonic anhydrase XI |
| CADM3 | cell adhesion molecule 3 |
| CARD9 | caspase recruitment domain family, member 9 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CDC25A | cell division cycle 25A |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CHRM4 | cholinergic receptor, muscarinic 4 |
| CYP19A1 | cytochrome P450, family 19, subfamily A, polypeptide 1 |
| CYP2D6 | cytochrome P450, family 2, subfamily D, polypeptide 6 |
| CYP2E1 | cytochrome P450, family 2, subfamily E, polypeptide 1 |
| DENND3 | DENN/MADD domain containing 3 |
| DGCR5 | DiGeorge syndrome critical region gene 5 (non-protein coding) |
| DIXDC1 | DIX domain containing 1 |
| DST | dystonin |
| ESR2 | estrogen receptor 2 (ER beta) |
| FAT2 | FAT atypical cadherin 2 |
| FBXO38 | F-box protein 38 |
| FCAR | Fc fragment of IgA receptor |
| FGR | FGR proto-oncogene, Src family tyrosine kinase |
| FRMPD1 | FERM and PDZ domain containing 1 |
| GAPDHS | glyceraldehyde-3-phosphate dehydrogenase, spermatogenic |
| GAS7 | growth arrest-specific 7 |
| GDF2 | growth differentiation factor 2 |
| GFAP | glial fibrillary acidic protein |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GNLY | granulysin |
| HOXD13 | homeobox D13 |
| HTN1 | histatin 1 |
| IL17A | interleukin 17A |
| IL1RN | interleukin 1 receptor antagonist |
| IL36RN | interleukin 36 receptor antagonist |
| ITFG2 | integrin alpha FG-GAP repeat containing 2 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KCTD13 | potassium channel tetramerization domain containing 13 |
| KLHL22 | kelch-like family member 22 |
| KRT5 | keratin 5, type II |
| LIAS | lipoic acid synthetase |
| LOC51145 | uncharacterized LOC51145 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| LUZP1 | leucine zipper protein 1 |
| MAPK8 | mitogen-activated protein kinase 8 |
| MAST2 | microtubule associated serine/threonine kinase 2 |
| MXRA5 | matrix-remodelling associated 5 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast |
| NCOA2 | nuclear receptor coactivator 2 |
| NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 |
| NPY4R | neuropeptide Y receptor Y4 |
| NR2C1 | nuclear receptor subfamily 2, group C, member 1 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| NRP1 | neuropilin 1 |
| OLFML2A | olfactomedin-like 2A |
| ORC4 | origin recognition complex, subunit 4 |
| P2RX7 | purinergic receptor P2X, ligand gated ion channel, 7 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
| PRDM14 | PR domain containing 14 |
| PRKD3 | protein kinase D3 |
| RND2 | Rho family GTPase 2 |
| RUNDC3A | RUN domain containing 3A |
| SBNO2 | strawberry notch homolog 2 (Drosophila) |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SFTPB | surfactant protein B |
| SMO | smoothened, frizzled class receptor |
| SPEG | SPEG complex locus |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| ST7L | suppression of tumorigenicity 7 like |
| STARD8 | StAR-related lipid transfer (START) domain containing 8 |
| STX2 | syntaxin 2 |
| SUSD4 | sushi domain containing 4 |
| SYNGR1 | synaptogyrin 1 |
| TAF1C | TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa |
| TGM4 | transglutaminase 4 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TMEM161A | transmembrane protein 161A |
| TNF | tumor necrosis factor |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
| TRIB2 | tribbles pseudokinase 2 |
| TRIL | TLR4 interactor with leucine-rich repeats |
| TTLL4 | tubulin tyrosine ligase-like family member 4 |
| USP48 | ubiquitin specific peptidase 48 |
| VARS | valyl-tRNA synthetase |
| ZNF460 | zinc finger protein 460 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ALPK1 | alpha-kinase 1 |
| ALX3 | ALX homeobox 3 |
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit |
| APBA1 | amyloid beta (A4) precursor protein-binding, family A, member 1 |
| APOH | apolipoprotein H (beta-2-glycoprotein I) |
| AQP8 | aquaporin 8 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARHGEF6 | Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 |
| BTBD2 | BTB (POZ) domain containing 2 |
| CA7 | carbonic anhydrase VII |
| CAV3 | caveolin 3 |
| CCDC53 | coiled-coil domain containing 53 |
| CCDC87 | coiled-coil domain containing 87 |
| CD5 | CD5 molecule |
| CD79A | CD79a molecule, immunoglobulin-associated alpha |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CDK3 | cyclin-dependent kinase 3 |
| CHODL | chondrolectin |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| CPB2 | carboxypeptidase B2 (plasma) |
| CST5 | cystatin D |
| CTLA4 | cytotoxic T-lymphocyte-associated protein 4 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| DAGLA | diacylglycerol lipase, alpha |
| DGKG | diacylglycerol kinase, gamma 90kDa |
| DOK3 | docking protein 3 |
| DYSF | dysferlin |
| EPX | eosinophil peroxidase |
| EVPL | envoplakin |
| FLRT1 | fibronectin leucine rich transmembrane protein 1 |
| GAS8-AS1 | GAS8 antisense RNA 1 |
| GATA6 | GATA binding protein 6 |
| GLT8D2 | glycosyltransferase 8 domain containing 2 |
| GPR19 | G protein-coupled receptor 19 |
| HGSNAT | heparan-alpha-glucosaminide N-acetyltransferase |
| HOXB9 | homeobox B9 |
| HPX | hemopexin |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IHH | indian hedgehog |
| IL6 | interleukin 6 |
| ITGA8 | integrin, alpha 8 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIFC3 | kinesin family member C3 |
| KLK7 | kallikrein-related peptidase 7 |
| KRT75 | keratin 75, type II |
| MEF2D | myocyte enhancer factor 2D |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MPZ | myelin protein zero |
| MS4A12 | membrane-spanning 4-domains, subfamily A, member 12 |
| MYH13 | myosin, heavy chain 13, skeletal muscle |
| NIPAL2 | NIPA-like domain containing 2 |
| PDCD1 | programmed cell death 1 |
| PIP | prolactin-induced protein |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PNMT | phenylethanolamine N-methyltransferase |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
| PRSS2 | protease, serine, 2 (trypsin 2) |
| PTK6 | protein tyrosine kinase 6 |
| PTPRT | protein tyrosine phosphatase, receptor type, T |
| PXDC1 | PX domain containing 1 |
| RASL12 | RAS-like, family 12 |
| RDH8 | retinol dehydrogenase 8 (all-trans) |
| RGSL1 | regulator of G-protein signaling like 1 |
| RNF141 | ring finger protein 141 |
| RPH3A | rabphilin 3A |
| RPL10L | ribosomal protein L10-like |
| RSPH6A | radial spoke head 6 homolog A (Chlamydomonas) |
| S100A3 | S100 calcium binding protein A3 |
| SCGN | secretagogin, EF-hand calcium binding protein |
| SLC39A2 | solute carrier family 39 (zinc transporter), member 2 |
| SLC6A5 | solute carrier family 6 (neurotransmitter transporter), member 5 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SNCB | synuclein, beta |
| SNX10 | sorting nexin 10 |
| SOX21 | SRY (sex determining region Y)-box 21 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| SYN1 | synapsin I |
| TK1 | thymidine kinase 1, soluble |
| TMEM209 | transmembrane protein 209 |
| TMPRSS6 | transmembrane protease, serine 6 |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TNNC2 | troponin C type 2 (fast) |
| TRAF2 | TNF receptor-associated factor 2 |
| TSHZ2 | teashirt zinc finger homeobox 2 |
| TSSC4 | tumor suppressing subtransferable candidate 4 |
| TTR | transthyretin |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| WNT2 | wingless-type MMTV integration site family member 2 |
| ZC4H2 | zinc finger, C4H2 domain containing |
| ZNF358 | zinc finger protein 358 |
| ZNF536 | zinc finger protein 536 |