exisulind-314 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the exisulind-314 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2
ADD2 adducin 2 (beta)
ADGRL3 adhesion G protein-coupled receptor L3
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ALDH3B2 aldehyde dehydrogenase 3 family, member B2
ANK1 ankyrin 1, erythrocytic
ARSA arylsulfatase A
ATP11A ATPase, class VI, type 11A
BCL6 B-cell CLL/lymphoma 6
C16ORF59 chromosome 16 open reading frame 59
C19ORF66 chromosome 19 open reading frame 66
C2ORF27A chromosome 2 open reading frame 27A
CA11 carbonic anhydrase XI
CADM3 cell adhesion molecule 3
CARD9 caspase recruitment domain family, member 9
CASP10 caspase 10, apoptosis-related cysteine peptidase
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CDC25A cell division cycle 25A
CDRT1 CMT1A duplicated region transcript 1
CHRM4 cholinergic receptor, muscarinic 4
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DENND3 DENN/MADD domain containing 3
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
DIXDC1 DIX domain containing 1
DST dystonin
ESR2 estrogen receptor 2 (ER beta)
FAT2 FAT atypical cadherin 2
FBXO38 F-box protein 38
FCAR Fc fragment of IgA receptor
FGR FGR proto-oncogene, Src family tyrosine kinase
FRMPD1 FERM and PDZ domain containing 1
GAPDHS glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
GAS7 growth arrest-specific 7
GDF2 growth differentiation factor 2
GFAP glial fibrillary acidic protein
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNLY granulysin
HOXD13 homeobox D13
HTN1 histatin 1
IL17A interleukin 17A
IL1RN interleukin 1 receptor antagonist
IL36RN interleukin 36 receptor antagonist
ITFG2 integrin alpha FG-GAP repeat containing 2
ITPKB inositol-trisphosphate 3-kinase B
KCTD13 potassium channel tetramerization domain containing 13
KLHL22 kelch-like family member 22
KRT5 keratin 5, type II
LIAS lipoic acid synthetase
LOC51145 uncharacterized LOC51145
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LTBP4 latent transforming growth factor beta binding protein 4
LUZP1 leucine zipper protein 1
MAPK8 mitogen-activated protein kinase 8
MAST2 microtubule associated serine/threonine kinase 2
MXRA5 matrix-remodelling associated 5
MYL1 myosin, light chain 1, alkali; skeletal, fast
NCOA2 nuclear receptor coactivator 2
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NPY4R neuropeptide Y receptor Y4
NR2C1 nuclear receptor subfamily 2, group C, member 1
NR6A1 nuclear receptor subfamily 6, group A, member 1
NRP1 neuropilin 1
OLFML2A olfactomedin-like 2A
ORC4 origin recognition complex, subunit 4
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PDE4DIP phosphodiesterase 4D interacting protein
PIEZO2 piezo-type mechanosensitive ion channel component 2
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PRDM14 PR domain containing 14
PRKD3 protein kinase D3
RND2 Rho family GTPase 2
RUNDC3A RUN domain containing 3A
SBNO2 strawberry notch homolog 2 (Drosophila)
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFTPB surfactant protein B
SMO smoothened, frizzled class receptor
SPEG SPEG complex locus
SPTBN1 spectrin, beta, non-erythrocytic 1
ST7L suppression of tumorigenicity 7 like
STARD8 StAR-related lipid transfer (START) domain containing 8
STX2 syntaxin 2
SUSD4 sushi domain containing 4
SYNGR1 synaptogyrin 1
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TGM4 transglutaminase 4
TIMP3 TIMP metallopeptidase inhibitor 3
TINAGL1 tubulointerstitial nephritis antigen-like 1
TMEM161A transmembrane protein 161A
TNF tumor necrosis factor
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TRIB2 tribbles pseudokinase 2
TRIL TLR4 interactor with leucine-rich repeats
TTLL4 tubulin tyrosine ligase-like family member 4
USP48 ubiquitin specific peptidase 48
VARS valyl-tRNA synthetase
ZNF460 zinc finger protein 460

decreased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ALPK1 alpha-kinase 1
ALX3 ALX homeobox 3
AP4M1 adaptor-related protein complex 4, mu 1 subunit
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
APOH apolipoprotein H (beta-2-glycoprotein I)
AQP8 aquaporin 8
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
BTBD2 BTB (POZ) domain containing 2
CA7 carbonic anhydrase VII
CAV3 caveolin 3
CCDC53 coiled-coil domain containing 53
CCDC87 coiled-coil domain containing 87
CD5 CD5 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CDADC1 cytidine and dCMP deaminase domain containing 1
CDK3 cyclin-dependent kinase 3
CHODL chondrolectin
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
CPB2 carboxypeptidase B2 (plasma)
CST5 cystatin D
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CUBN cubilin (intrinsic factor-cobalamin receptor)
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DAGLA diacylglycerol lipase, alpha
DGKG diacylglycerol kinase, gamma 90kDa
DOK3 docking protein 3
DYSF dysferlin
EPX eosinophil peroxidase
EVPL envoplakin
FLRT1 fibronectin leucine rich transmembrane protein 1
GAS8-AS1 GAS8 antisense RNA 1
GATA6 GATA binding protein 6
GLT8D2 glycosyltransferase 8 domain containing 2
GPR19 G protein-coupled receptor 19
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HOXB9 homeobox B9
HPX hemopexin
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IHH indian hedgehog
IL6 interleukin 6
ITGA8 integrin, alpha 8
KDM8 lysine (K)-specific demethylase 8
KIFC3 kinesin family member C3
KLK7 kallikrein-related peptidase 7
KRT75 keratin 75, type II
MEF2D myocyte enhancer factor 2D
MFSD11 major facilitator superfamily domain containing 11
MPZ myelin protein zero
MS4A12 membrane-spanning 4-domains, subfamily A, member 12
MYH13 myosin, heavy chain 13, skeletal muscle
NIPAL2 NIPA-like domain containing 2
PDCD1 programmed cell death 1
PIP prolactin-induced protein
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PNMT phenylethanolamine N-methyltransferase
POLD4 polymerase (DNA-directed), delta 4, accessory subunit
PRSS2 protease, serine, 2 (trypsin 2)
PTK6 protein tyrosine kinase 6
PTPRT protein tyrosine phosphatase, receptor type, T
PXDC1 PX domain containing 1
RASL12 RAS-like, family 12
RDH8 retinol dehydrogenase 8 (all-trans)
RGSL1 regulator of G-protein signaling like 1
RNF141 ring finger protein 141
RPH3A rabphilin 3A
RPL10L ribosomal protein L10-like
RSPH6A radial spoke head 6 homolog A (Chlamydomonas)
S100A3 S100 calcium binding protein A3
SCGN secretagogin, EF-hand calcium binding protein
SLC39A2 solute carrier family 39 (zinc transporter), member 2
SLC6A5 solute carrier family 6 (neurotransmitter transporter), member 5
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SNCB synuclein, beta
SNX10 sorting nexin 10
SOX21 SRY (sex determining region Y)-box 21
SPINK1 serine peptidase inhibitor, Kazal type 1
SYN1 synapsin I
TK1 thymidine kinase 1, soluble
TMEM209 transmembrane protein 209
TMPRSS6 transmembrane protease, serine 6
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNNC2 troponin C type 2 (fast)
TRAF2 TNF receptor-associated factor 2
TSHZ2 teashirt zinc finger homeobox 2
TSSC4 tumor suppressing subtransferable candidate 4
TTR transthyretin
UNC93B1 unc-93 homolog B1 (C. elegans)
WNT10B wingless-type MMTV integration site family, member 10B
WNT2 wingless-type MMTV integration site family member 2
ZC4H2 zinc finger, C4H2 domain containing
ZNF358 zinc finger protein 358
ZNF536 zinc finger protein 536