exocytosis Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell. This is the process in which most molecules are secreted from eukaryotic cells. (Gene Ontology, GO_0006887)
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Genes

183 genes co-occuring with the biological term exocytosis in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACPP acid phosphatase, prostate
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANGPT2 angiopoietin 2
ANXA11 annexin A11
ANXA2 annexin A2
ANXA3 annexin A3
AP1B1 adaptor-related protein complex 1, beta 1 subunit
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
AQP12A aquaporin 12A
AQP2 aquaporin 2 (collecting duct)
ARF1 ADP-ribosylation factor 1
ARF6 ADP-ribosylation factor 6
ATF4 activating transcription factor 4
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATP7B ATPase, Cu++ transporting, beta polypeptide
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CAPN10 calpain 10
CASP8 caspase 8, apoptosis-related cysteine peptidase
CDK5 cyclin-dependent kinase 5
CHGA chromogranin A
CHGB chromogranin B
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal)
CIT citron rho-interacting serine/threonine kinase
CLCN4 chloride channel, voltage-sensitive 4
CPLX1 complexin 1
CPLX2 complexin 2
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTSB cathepsin B
CYBB cytochrome b-245, beta polypeptide
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DGKE diacylglycerol kinase, epsilon 64kDa
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5
EBAG9 estrogen receptor binding site associated, antigen, 9
EXOC2 exocyst complex component 2
FCGRT Fc fragment of IgG, receptor, transporter, alpha
FHOD1 formin homology 2 domain containing 1
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
FPR2 formyl peptide receptor 2
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GIP gastric inhibitory polypeptide
GMIP GEM interacting protein
GP1BB glycoprotein Ib (platelet), beta polypeptide
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HMGB1 high mobility group box 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPB1 heat shock 27kDa protein 1
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HTT huntingtin
HYAL3 hyaluronoglucosaminidase 3
IDS iduronate 2-sulfatase
IGHE immunoglobulin heavy constant epsilon
IL15 interleukin 15
IL15RA interleukin 15 receptor, alpha
IL2 interleukin 2
INS insulin
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITSN1 intersectin 1 (SH3 domain protein)
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KDR kinase insert domain receptor
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2
KLK3 kallikrein-related peptidase 3
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LTB4R leukotriene B4 receptor
MARCKS myristoylated alanine-rich protein kinase C substrate
MCOLN1 mucolipin 1
MFN1 mitofusin 1
MIR7-1 microRNA 7-1
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYH9 myosin, heavy chain 9, non-muscle
NEU1 sialidase 1 (lysosomal sialidase)
NEUROD1 neuronal differentiation 1
NEUROG3 neurogenin 3
NOS3 nitric oxide synthase 3 (endothelial cell)
NSF N-ethylmaleimide-sensitive factor
NUCB2 nucleobindin 2
ORAI1 ORAI calcium release-activated calcium modulator 1
OTOF otoferlin
OXT oxytocin/neurophysin I prepropeptide
P2RY11 purinergic receptor P2Y, G-protein coupled, 11
PF4 platelet factor 4
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLA2G2D phospholipase A2, group IID
PLAT plasminogen activator, tissue
PLD1 phospholipase D1, phosphatidylcholine-specific
PLSCR1 phospholipid scramblase 1
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKCI protein kinase C, iota
RAB11A RAB11A, member RAS oncogene family
RAB11B RAB11B, member RAS oncogene family
RAB27A RAB27A, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RAB3B RAB3B, member RAS oncogene family
RAB3D RAB3D, member RAS oncogene family
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RAB4A RAB4A, member RAS oncogene family
RAB6A RAB6A, member RAS oncogene family
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RALB v-ral simian leukemia viral oncogene homolog B
RALGDS ral guanine nucleotide dissociation stimulator
RAP1A RAP1A, member of RAS oncogene family
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1
RAP2A RAP2A, member of RAS oncogene family
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RCAN1 regulator of calcineurin 1
REM2 RAS (RAD and GEM)-like GTP binding 2
REST RE1-silencing transcription factor
RGS7 regulator of G-protein signaling 7
RHOQ ras homolog family member Q
RIMS1 regulating synaptic membrane exocytosis 1
RIMS2 regulating synaptic membrane exocytosis 2
RPH3A rabphilin 3A
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
S100A10 S100 calcium binding protein A10
S100A11 S100 calcium binding protein A11
SCAMP2 secretory carrier membrane protein 2
SCAMP5 secretory carrier membrane protein 5
SFRP4 secreted frizzled-related protein 4
SLC17A9 solute carrier family 17 (vesicular nucleotide transporter), member 9
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SNAP23 synaptosomal-associated protein, 23kDa
SNAP25 synaptosomal-associated protein, 25kDa
SNAPIN SNAP-associated protein
SNAR-E small ILF3/NF90-associated RNA E
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOD1 superoxide dismutase 1, soluble
SST somatostatin
SSTR2 somatostatin receptor 2
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STX11 syntaxin 11
STX1A syntaxin 1A (brain)
STX3 syntaxin 3
STX4 syntaxin 4
STX7 syntaxin 7
STXBP1 syntaxin binding protein 1
STXBP2 syntaxin binding protein 2
STXBP3 syntaxin binding protein 3
STXBP5 syntaxin binding protein 5 (tomosyn)
SYT1 synaptotagmin I
SYT12 synaptotagmin XII
SYT4 synaptotagmin IV
SYT6 synaptotagmin VI
SYTL1 synaptotagmin-like 1
SYTL4 synaptotagmin-like 4
TERF2IP telomeric repeat binding factor 2, interacting protein
TFE3 transcription factor binding to IGHM enhancer 3
TFEB transcription factor EB
TLR2 toll-like receptor 2
TRIB3 tribbles pseudokinase 3
TXN thioredoxin
UNC13A unc-13 homolog A (C. elegans)
UNC13B unc-13 homolog B (C. elegans)
UNC13D unc-13 homolog D (C. elegans)
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VAMP7 vesicle-associated membrane protein 7
VAMP8 vesicle-associated membrane protein 8
VEGFA vascular endothelial growth factor A
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
VWF von Willebrand factor
WARS tryptophanyl-tRNA synthetase
WWC1 WW and C2 domain containing 1
XPO1 exportin 1
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
ZP1 zona pellucida glycoprotein 1 (sperm receptor)
ZP2 zona pellucida glycoprotein 2 (sperm receptor)
ZP3 zona pellucida glycoprotein 3 (sperm receptor)
ZP4 zona pellucida glycoprotein 4