exogenous Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

341 genes co-occuring with the biological term exogenous in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACLY ATP citrate lyase
ACSL4 acyl-CoA synthetase long-chain family member 4
ACSS2 acyl-CoA synthetase short-chain family member 2
ADAR adenosine deaminase, RNA-specific
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADM adrenomedullin
AGTR1 angiotensin II receptor, type 1
AHI1 Abelson helper integration site 1
AHR aryl hydrocarbon receptor
AICDA activation-induced cytidine deaminase
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANPEP alanyl (membrane) aminopeptidase
ANXA5 annexin A5
APOA1 apolipoprotein A-I
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
AR androgen receptor
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ASIC1 acid sensing (proton gated) ion channel 1
ASIC4 acid sensing (proton gated) ion channel family member 4
ATM ATM serine/threonine kinase
ATOX1 antioxidant 1 copper chaperone
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATXN3 ataxin 3
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BDNF brain-derived neurotrophic factor
BIRC5 baculoviral IAP repeat containing 5
BMP7 bone morphogenetic protein 7
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BTK Bruton agammaglobulinemia tyrosine kinase
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CASP14 caspase 14, apoptosis-related cysteine peptidase
CCND1 cyclin D1
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD1A CD1a molecule
CD1B CD1b molecule
CD1C CD1c molecule
CD1D CD1d molecule
CD247 CD247 molecule
CD274 CD274 molecule
CD28 CD28 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CDC25C cell division cycle 25C
CDCP1 CUB domain containing protein 1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDT1 chromatin licensing and DNA replication factor 1
CFH complement factor H
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CLU clusterin
COL1A1 collagen, type I, alpha 1
CRH corticotropin releasing hormone
CRHR1 corticotropin releasing hormone receptor 1
CSF1R colony stimulating factor 1 receptor
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CSN2 casein beta
CSPG4 chondroitin sulfate proteoglycan 4
CSTA cystatin A (stefin A)
CTTN cortactin
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DEFB4A defensin, beta 4A
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNASE2B deoxyribonuclease II beta
DUOX2 dual oxidase 2
DUOXA2 dual oxidase maturation factor 2
EGFR epidermal growth factor receptor
EGR1 early growth response 1
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPAS1 endothelial PAS domain protein 1
EPO erythropoietin
ERBB4 erb-b2 receptor tyrosine kinase 4
ESR2 estrogen receptor 2 (ER beta)
F13B coagulation factor XIII, B polypeptide
F3 coagulation factor III (thromboplastin, tissue factor)
FBL fibrillarin
FGF1 fibroblast growth factor 1 (acidic)
FGF12 fibroblast growth factor 12
FGF2 fibroblast growth factor 2 (basic)
FGF7 fibroblast growth factor 7
FGFR1 fibroblast growth factor receptor 1
FHIT fragile histidine triad
FKBP5 FK506 binding protein 5
FLT3LG fms-related tyrosine kinase 3 ligand
FOXO3 forkhead box O3
FSHR follicle stimulating hormone receptor
G6PD glucose-6-phosphate dehydrogenase
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GDF5 growth differentiation factor 5
GEMIN5 gem (nuclear organelle) associated protein 5
GH1 growth hormone 1
GHRL ghrelin/obestatin prepropeptide
GJD3 gap junction protein, delta 3, 31.9kDa
GLP1R glucagon-like peptide 1 receptor
GPC3 glypican 3
GRAP2 GRB2-related adaptor protein 2
HEPACAM hepatic and glial cell adhesion molecule
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HMGB1 high mobility group box 1
HMOX1 heme oxygenase 1
HRAS Harvey rat sarcoma viral oncogene homolog
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA9 heat shock 70kDa protein 9 (mortalin)
HTN3 histatin 3
IAPP islet amyloid polypeptide
ICMT isoprenylcysteine carboxyl methyltransferase
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP3 insulin-like growth factor binding protein 3
IGFBP5 insulin-like growth factor binding protein 5
IGL immunoglobulin lambda locus
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL10 interleukin 10
IL11 interleukin 11
IL15 interleukin 15
IL18 interleukin 18
IL18BP interleukin 18 binding protein
IL1B interleukin 1, beta
IL2 interleukin 2
IL2RB interleukin 2 receptor, beta
IL4 interleukin 4
IL6 interleukin 6
IL7 interleukin 7
IL7R interleukin 7 receptor
ING4 inhibitor of growth family, member 4
INHBA inhibin, beta A
INS insulin
IPO7 importin 7
IRAK1 interleukin-1 receptor-associated kinase 1
IRS1 insulin receptor substrate 1
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB6 integrin, beta 6
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KIF5B kinesin family member 5B
KISS1 KiSS-1 metastasis-suppressor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
KLF2 Kruppel-like factor 2
LACRT lacritin
LAMA5 laminin, alpha 5
LAMB1 laminin, beta 1
LAMC1 laminin, gamma 1 (formerly LAMB2)
LAMP2 lysosomal-associated membrane protein 2
LGALS3 lectin, galactoside-binding, soluble, 3
LRP1 low density lipoprotein receptor-related protein 1
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPT microtubule-associated protein tau
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCM2 minichromosome maintenance complex component 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR141 microRNA 141
MIR155 microRNA 155
MIR21 microRNA 21
MIR370 microRNA 370
MIR9-1 microRNA 9-1
MMP13 matrix metallopeptidase 13
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MR1 major histocompatibility complex, class I-related
MSTN myostatin
MTTP microsomal triglyceride transfer protein
MUC1 mucin 1, cell surface associated
MUC17 mucin 17, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MXRA8 matrix-remodelling associated 8
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NAMPT nicotinamide phosphoribosyltransferase
NFE2L2 nuclear factor, erythroid 2-like 2
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NGF nerve growth factor (beta polypeptide)
NKX3-2 NK3 homeobox 2
NME2 NME/NM23 nucleoside diphosphate kinase 2
NMNAT1 nicotinamide nucleotide adenylyltransferase 1
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NOTCH2 notch 2
NOX1 NADPH oxidase 1
NOX4 NADPH oxidase 4
NPPB natriuretic peptide B
NR0B2 nuclear receptor subfamily 0, group B, member 2
NR1I3 nuclear receptor subfamily 1, group I, member 3
NTF3 neurotrophin 3
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
ORAI1 ORAI calcium release-activated calcium modulator 1
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PARD6A par-6 family cell polarity regulator alpha
PCNA proliferating cell nuclear antigen
PDCD5 programmed cell death 5
PDGFA platelet-derived growth factor alpha polypeptide
PDGFB platelet-derived growth factor beta polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDIA3 protein disulfide isomerase family A, member 3
PEG10 paternally expressed 10
PHF2 PHD finger protein 2
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PKDCC protein kinase domain containing, cytoplasmic
PLA2G10 phospholipase A2, group X
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
PNPLA6 patatin-like phospholipase domain containing 6
POU2F1 POU class 2 homeobox 1
POU5F1 POU class 5 homeobox 1
PPARG peroxisome proliferator-activated receptor gamma
PRL prolactin
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PRTN3 proteinase 3
PSEN1 presenilin 1
PSEN2 presenilin 2
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH parathyroid hormone
RAB3B RAB3B, member RAS oncogene family
RAB3C RAB3C, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAD51 RAD51 recombinase
RAG1 recombination activating gene 1
RAG2 recombination activating gene 2
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RARB retinoic acid receptor, beta
RCOR2 REST corepressor 2
RECQL4 RecQ protein-like 4
RET ret proto-oncogene
RHOA ras homolog family member A
RNF2 ring finger protein 2
ROR2 receptor tyrosine kinase-like orphan receptor 2
S100A7A S100 calcium binding protein A7A
SAT1 spermidine/spermine N1-acetyltransferase 1
SCARB1 scavenger receptor class B, member 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCG5 secretogranin V
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SCO2 SCO2 cytochrome c oxidase assembly protein
SDC1 syndecan 1
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SERPINA12 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SETMAR SET domain and mariner transposase fusion gene
SFTPA1 surfactant protein A1
SFTPA2 surfactant protein A2
SH2D1A SH2 domain containing 1A
SHH sonic hedgehog
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin
SLAMF1 signaling lymphocytic activation molecule family member 1
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOCS5 suppressor of cytokine signaling 5
SOCS7 suppressor of cytokine signaling 7
SORT1 sortilin 1
SOX2 SRY (sex determining region Y)-box 2
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPAST spastin
SPDYA speedy/RINGO cell cycle regulator family member A
SPHK1 sphingosine kinase 1
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SPP1 secreted phosphoprotein 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SSTR2 somatostatin receptor 2
SSTR5 somatostatin receptor 5
STAT1 signal transducer and activator of transcription 1, 91kDa
STK11 serine/threonine kinase 11
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TARDBP TAR DNA binding protein
TDG thymine-DNA glycosylase
TERT telomerase reverse transcriptase
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGFB3 transforming growth factor, beta 3
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGFBR3 transforming growth factor, beta receptor III
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TMPRSS9 transmembrane protease, serine 9
TNF tumor necrosis factor
TOLLIP toll interacting protein
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TP53 tumor protein p53
TP73 tumor protein p73
TRA T cell receptor alpha locus
TRB T cell receptor beta locus
TREH trehalase (brush-border membrane glycoprotein)
TSC22D3 TSC22 domain family, member 3
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast)
VASH1 vasohibin 1
VASP vasodilator-stimulated phosphoprotein
VCAM1 vascular cell adhesion molecule 1
VCP valosin containing protein
VEGFA vascular endothelial growth factor A
VSX2 visual system homeobox 2
WAS Wiskott-Aldrich syndrome
WFDC1 WAP four-disulfide core domain 1
WNT3A wingless-type MMTV integration site family, member 3A
WT1 Wilms tumor 1
WWOX WW domain containing oxidoreductase
XDH xanthine dehydrogenase
ZEB2 zinc finger E-box binding homeobox 2
ZMIZ1 zinc finger, MIZ-type containing 1