exopeptidase activity Gene Set

Dataset GO Molecular Function Annotations 2025
Category structural or functional annotations
Type molecular function
Description Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain, in a reaction that requires a free N-terminal amino group, C-terminal carboxyl group or both. (Gene Ontology, GO_0008238)
External Link http://amigo.geneontology.org/amigo/term/GO:0008238
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Genes

54 genes performing the exopeptidase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

Symbol Name
ACE angiotensin I converting enzyme
ACE2 angiotensin I converting enzyme 2
ANPEP alanyl (membrane) aminopeptidase
ATG4D autophagy related 4D, cysteine peptidase
BLMH bleomycin hydrolase
CNDP1 carnosine dipeptidase 1 (metallopeptidase M20 family)
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family)
CPA2 carboxypeptidase A2 (pancreatic)
CPB1 carboxypeptidase B1 (tissue)
CPE carboxypeptidase E
CPM carboxypeptidase M
CTSA cathepsin A
CTSH cathepsin H
CTSZ cathepsin Z
DPEP1 dipeptidase 1 (renal)
DPEP2 dipeptidase 2
DPEP3 dipeptidase 3
DPP10 dipeptidyl-peptidase 10 (non-functional)
DPP3 dipeptidyl-peptidase 3
DPP4 dipeptidyl-peptidase 4
DPP6 dipeptidyl-peptidase 6
DPP7 dipeptidyl-peptidase 7
DPP8 dipeptidyl-peptidase 8
DPP9 dipeptidyl-peptidase 9
ENPEP glutamyl aminopeptidase (aminopeptidase A)
ERAP1 endoplasmic reticulum aminopeptidase 1
ERAP2 endoplasmic reticulum aminopeptidase 2
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GLMN glomulin, FKBP associated protein
JMJD7 jumonji domain containing 7
KDM8 lysine (K)-specific demethylase 8
LAP3 leucine aminopeptidase 3
LNPEP leucyl/cystinyl aminopeptidase
LTA4H leukotriene A4 hydrolase
METAP1 methionyl aminopeptidase 1
METAP1D methionyl aminopeptidase type 1D (mitochondrial)
METAP2 methionyl aminopeptidase 2
MMP12 matrix metallopeptidase 12
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NAALADL1 N-acetylated alpha-linked acidic dipeptidase-like 1
NPEPPS aminopeptidase puromycin sensitive
NUDT16 nudix (nucleoside diphosphate linked moiety X)-type motif 16
PM20D2 peptidase M20 domain containing 2
PRCP prolylcarboxypeptidase (angiotensinase C)
PRSS16 protease, serine, 16 (thymus)
RCE1 Ras converting CAAX endopeptidase 1
RNPEP arginyl aminopeptidase (aminopeptidase B)
TPP2 tripeptidyl peptidase II
TRHDE thyrotropin-releasing hormone degrading enzyme
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
XPNPEP2 X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZMPSTE24 zinc metallopeptidase STE24