expansion Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

400 genes co-occuring with the biological term expansion in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACTA1 actin, alpha 1, skeletal muscle
ADAM10 ADAM metallopeptidase domain 10
ADD1 adducin 1 (alpha)
ADIPOQ adiponectin, C1Q and collagen domain containing
ADRB2 adrenoceptor beta 2, surface
AHR aryl hydrocarbon receptor
AICDA activation-induced cytidine deaminase
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALDH18A1 aldehyde dehydrogenase 18 family, member A1
ALK anaplastic lymphoma receptor tyrosine kinase
ANGPT2 angiopoietin 2
APC adenomatous polyposis coli
APOA1 apolipoprotein A-I
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
APTX aprataxin
AR androgen receptor
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7
ARRB1 arrestin, beta 1
ARX aristaless related homeobox
ATF6 activating transcription factor 6
ATM ATM serine/threonine kinase
ATN1 atrophin 1
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
ATXN1 ataxin 1
ATXN10 ataxin 10
ATXN2 ataxin 2
ATXN3 ataxin 3
ATXN7 ataxin 7
ATXN8 ataxin 8
ATXN8OS ATXN8 opposite strand (non-protein coding)
AURKB aurora kinase B
B3GAT1 beta-1,3-glucuronyltransferase 1
BCL3 B-cell CLL/lymphoma 3
BCL6 B-cell CLL/lymphoma 6
BCR breakpoint cluster region
BDNF brain-derived neurotrophic factor
BIRC2 baculoviral IAP repeat containing 2
BIRC3 baculoviral IAP repeat containing 3
BIRC5 baculoviral IAP repeat containing 5
BMI1 BMI1 proto-oncogene, polycomb ring finger
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
BMPR1B bone morphogenetic protein receptor, type IB
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
BTK Bruton agammaglobulinemia tyrosine kinase
BTLA B and T lymphocyte associated
C1ORF186 chromosome 1 open reading frame 186
C9ORF72 chromosome 9 open reading frame 72
CA9 carbonic anhydrase IX
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CALCA calcitonin-related polypeptide alpha
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCL2 chemokine (C-C motif) ligand 2
CCL4 chemokine (C-C motif) ligand 4
CCNC cyclin C
CCND1 cyclin D1
CD14 CD14 molecule
CD19 CD19 molecule
CD1C CD1c molecule
CD1D CD1d molecule
CD27 CD27 molecule
CD274 CD274 molecule
CD28 CD28 molecule
CD34 CD34 molecule
CD4 CD4 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD63 CD63 molecule
CD70 CD70 molecule
CD80 CD80 molecule
CD86 CD86 molecule
CD8A CD8a molecule
CDC25A cell division cycle 25A
CDC42 cell division cycle 42
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CELF1 CUGBP, Elav-like family member 1
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CLU clusterin
CNBP CCHC-type zinc finger, nucleic acid binding protein
CORO1A coronin, actin binding protein, 1A
CR2 complement component (3d/Epstein Barr virus) receptor 2
CRABP2 cellular retinoic acid binding protein 2
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CSTB cystatin B (stefin B)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSS cathepsin S
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL12 chemokine (C-X-C motif) ligand 12
CXCR4 chemokine (C-X-C motif) receptor 4
CYR61 cysteine-rich, angiogenic inducer, 61
DENND2D DENN/MADD domain containing 2D
DGKA diacylglycerol kinase, alpha 80kDa
DGKZ diacylglycerol kinase, zeta
DLK1 delta-like 1 homolog (Drosophila)
DMD dystrophin
DMPK dystrophia myotonica-protein kinase
DNM1 dynamin 1
DOCK8 dedicator of cytokinesis 8
DUOX2 dual oxidase 2
EGFL6 EGF-like-domain, multiple 6
ELN elastin
ELP3 elongator acetyltransferase complex subunit 3
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EPOR erythropoietin receptor
ERCC6 excision repair cross-complementation group 6
ERN1 endoplasmic reticulum to nucleus signaling 1
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FABP12 fatty acid binding protein 12
FADD Fas (TNFRSF6)-associated via death domain
FANCD2 Fanconi anemia, complementation group D2
FANCL Fanconi anemia, complementation group L
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
FCRL5 Fc receptor-like 5
FEN1 flap structure-specific endonuclease 1
FGF10 fibroblast growth factor 10
FGF7 fibroblast growth factor 7
FGF9 fibroblast growth factor 9
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FLT1 fms-related tyrosine kinase 1
FLT3LG fms-related tyrosine kinase 3 ligand
FMOD fibromodulin
FMR1 fragile X mental retardation 1
FMR1-AS1 FMR1 antisense RNA 1
FOXE1 forkhead box E1
FOXL2 forkhead box L2
FOXP3 forkhead box P3
FXN frataxin
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GATA1 GATA binding protein 1 (globin transcription factor 1)
GATA2 GATA binding protein 2
GATA3 GATA binding protein 3
GFI1B growth factor independent 1B transcription repressor
GHRH growth hormone releasing hormone
GJA1 gap junction protein, alpha 1, 43kDa
GLI1 GLI family zinc finger 1
GNL3L guanine nucleotide binding protein-like 3 (nucleolar)-like
GRN granulin
GSK3B glycogen synthase kinase 3 beta
GSTO1 glutathione S-transferase omega 1
H2AFX H2A histone family, member X
HAVCR2 hepatitis A virus cellular receptor 2
HBB hemoglobin, beta
HDAC3 histone deacetylase 3
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-G major histocompatibility complex, class I, G
HMGA2 high mobility group AT-hook 2
HMOX1 heme oxygenase 1
HNF1A HNF1 homeobox A
HOXA13 homeobox A13
HOXD13 homeobox D13
HTN3 histatin 3
HTT huntingtin
ICOSLG inducible T-cell co-stimulator ligand
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IDO1 indoleamine 2,3-dioxygenase 1
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IGFALS insulin-like growth factor binding protein, acid labile subunit
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP4 insulin-like growth factor binding protein 4
IHH indian hedgehog
IKZF2 IKAROS family zinc finger 2 (Helios)
IL10 interleukin 10
IL12A interleukin 12A
IL12RB1 interleukin 12 receptor, beta 1
IL13 interleukin 13
IL15 interleukin 15
IL15RA interleukin 15 receptor, alpha
IL17A interleukin 17A
IL17RA interleukin 17 receptor A
IL18 interleukin 18
IL2 interleukin 2
IL21 interleukin 21
IL25 interleukin 25
IL27 interleukin 27
IL2RA interleukin 2 receptor, alpha
IL2RB interleukin 2 receptor, beta
IL2RG interleukin 2 receptor, gamma
IL32 interleukin 32
IL33 interleukin 33
IL4 interleukin 4
IL4I1 interleukin 4 induced 1
IL6 interleukin 6
IL7 interleukin 7
IL7R interleukin 7 receptor
IL9 interleukin 9
ISL1 ISL LIM homeobox 1
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1
ITK IL2-inducible T-cell kinase
JAG1 jagged 1
JAK2 Janus kinase 2
JMJD1C jumonji domain containing 1C
JPH3 junctophilin 3
KCNN3 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 3
KDR kinase insert domain receptor
KEAP1 kelch-like ECH-associated protein 1
KIR2DS2 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 2
KIR2DS4 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2
KIR3DS1 killer cell immunoglobulin-like receptor, three domains, short cytoplasmic tail, 1
KITLG KIT ligand
KLK1 kallikrein 1
KLRC2 killer cell lectin-like receptor subfamily C, member 2
KLRD1 killer cell lectin-like receptor subfamily D, member 1
KLRG1 killer cell lectin-like receptor subfamily G, member 1
KLRK1 killer cell lectin-like receptor subfamily K, member 1
LCK LCK proto-oncogene, Src family tyrosine kinase
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
LIF leukemia inhibitory factor
LIN28A lin-28 homolog A (C. elegans)
LMO2 LIM domain only 2 (rhombotin-like 1)
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
MAPK8 mitogen-activated protein kinase 8
MAPT microtubule-associated protein tau
MARCO macrophage receptor with collagenous structure
MCL1 myeloid cell leukemia 1
MCOLN3 mucolipin 3
MECOM MDS1 and EVI1 complex locus
MECP2 methyl CpG binding protein 2
MEDAG mesenteric estrogen-dependent adipogenesis
MICA MHC class I polypeptide-related sequence A
MIR146A microRNA 146a
MIR155 microRNA 155
MIR17 microRNA 17
MIR17HG miR-17-92 cluster host gene
MIR21 microRNA 21
MIR223 microRNA 223
MIR363 microRNA 363
MMP12 matrix metallopeptidase 12
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP7 matrix metallopeptidase 7
MPL MPL proto-oncogene, thrombopoietin receptor
MRC1 mannose receptor, C type 1
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MSH2 mutS homolog 2
MSH3 mutS homolog 3
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUS81 MUS81 structure-specific endonuclease subunit
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NCAM1 neural cell adhesion molecule 1
NFE2 nuclear factor, erythroid 2
NGFR nerve growth factor receptor
NOD2 nucleotide-binding oligomerization domain containing 2
NOG noggin
NOP56 NOP56 ribonucleoprotein
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NOTCH3 notch 3
NPNT nephronectin
NPPB natriuretic peptide B
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRG1 neuregulin 1
NTF3 neurotrophin 3
NTN1 netrin 1
OPA1 optic atrophy 1 (autosomal dominant)
PABPN1 poly(A) binding protein, nuclear 1
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PCNA proliferating cell nuclear antigen
PDCD1 programmed cell death 1
PDGFC platelet derived growth factor C
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PHOX2B paired-like homeobox 2b
PIGA phosphatidylinositol glycan anchor biosynthesis, class A
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PLAU plasminogen activator, urokinase
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLEKHG4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4
PLK2 polo-like kinase 2
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPARG peroxisome proliferator-activated receptor gamma
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PRAME preferentially expressed antigen in melanoma
PREP prolyl endopeptidase
PRNP prion protein
PROM1 prominin 1
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH parathyroid hormone
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTX3 pentraxin 3, long
PXN paxillin
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RBL1 retinoblastoma-like 1
RBL2 retinoblastoma-like 2
REG1A regenerating islet-derived 1 alpha
REG1B regenerating islet-derived 1 beta
REG3A regenerating islet-derived 3 alpha
REG4 regenerating islet-derived family, member 4
RELN reelin
RET ret proto-oncogene
RETN resistin
RIPK3 receptor-interacting serine-threonine kinase 3
RPL13A ribosomal protein L13a
RPL35 ribosomal protein L35
RPL7 ribosomal protein L7
RRBP1 ribosome binding protein 1
RUNX1 runt-related transcription factor 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
S100A9 S100 calcium binding protein A9
S100B S100 calcium binding protein B
SAA1 serum amyloid A1
SALL4 spalt-like transcription factor 4
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SCNN1G sodium channel, non voltage gated 1 gamma subunit
SCRG1 stimulator of chondrogenesis 1
SEC13 SEC13 homolog (S. cerevisiae)
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SH2B3 SH2B adaptor protein 3
SHH sonic hedgehog
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SMAD1 SMAD family member 1
SOCS3 suppressor of cytokine signaling 3
SOX2 SRY (sex determining region Y)-box 2
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPP1 secreted phosphoprotein 1
SQSTM1 sequestosome 1
SRF serum response factor (c-fos serum response element-binding transcription factor)
ST2 suppression of tumorigenicity 2
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
SYK spleen tyrosine kinase
TAC1 tachykinin, precursor 1
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TARDBP TAR DNA binding protein
TBP TATA box binding protein
TCF3 transcription factor 3
TCF4 transcription factor 4
TFF3 trefoil factor 3 (intestinal)
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGFB3 transforming growth factor, beta 3
THBD thrombomodulin
THPO thrombopoietin
TLR2 toll-like receptor 2
TMEM106B transmembrane protein 106B
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TNFRSF17 tumor necrosis factor receptor superfamily, member 17
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF12 tumor necrosis factor (ligand) superfamily, member 12
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TP53 tumor protein p53
TP63 tumor protein p63
TRA T cell receptor alpha locus
TRBV5-2 T cell receptor beta variable 5-2 (pseudogene)
TRDV2 T cell receptor delta variable 2
TRG T cell receptor gamma locus
TRGV9 T cell receptor gamma variable 9
TRNP1 TMF1-regulated nuclear protein 1
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TTPA tocopherol (alpha) transfer protein
TWIST1 twist family bHLH transcription factor 1
USP16 ubiquitin specific peptidase 16
UTRN utrophin
VASP vasodilator-stimulated phosphoprotein
VCAM1 vascular cell adhesion molecule 1
VCAN versican
VCP valosin containing protein
VDAC2 voltage-dependent anion channel 2
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VENTX VENT homeobox
VWF von Willebrand factor
WNT1 wingless-type MMTV integration site family, member 1
WNT3A wingless-type MMTV integration site family, member 3A
WT1 Wilms tumor 1
XBP1 X-box binding protein 1
YAP1 Yes-associated protein 1
ZIC2 Zic family member 2