exposure Gene Set

Dataset Phosphosite Textmining Biological Term Annotations
Category structural or functional annotations
Type biological term
Description The act of subjecting someone or something to an influencing experience. E.g. exposure to cigarette smoke (Experimental Factor Ontology, EFO_0000487)
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Genes

322 proteins co-occuring with the biological term exposure in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Symbol Name
AANAT aralkylamine N-acetyltransferase
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACACA acetyl-CoA carboxylase alpha
ACE angiotensin I converting enzyme
ACIN1 apoptotic chromatin condensation inducer 1
ADCY3 adenylate cyclase 3
ADD1 adducin 1 (alpha)
ADORA2A adenosine A2a receptor
ADRA2A adrenoceptor alpha 2A
ADRB1 adrenoceptor beta 1
ADRB2 adrenoceptor beta 2, surface
AHR aryl hydrocarbon receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALOX5 arachidonate 5-lipoxygenase
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
AQP2 aquaporin 2 (collecting duct)
AQP4 aquaporin 4
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
ARHGAP5 Rho GTPase activating protein 5
ASCL1 achaete-scute family bHLH transcription factor 1
ATF1 activating transcription factor 1
ATF2 activating transcription factor 2
ATM ATM serine/threonine kinase
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATR ATR serine/threonine kinase
AURKA aurora kinase A
AURKB aurora kinase B
AVPR2 arginine vasopressin receptor 2
BAD BCL2-associated agonist of cell death
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
BCHE butyrylcholinesterase
BCL10 B-cell CLL/lymphoma 10
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BIRC5 baculoviral IAP repeat containing 5
BLM Bloom syndrome, RecQ helicase-like
BRCA1 breast cancer 1, early onset
CACYBP calcyclin binding protein
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CASP8 caspase 8, apoptosis-related cysteine peptidase
CASR calcium-sensing receptor
CAV1 caveolin 1, caveolae protein, 22kDa
CCDC6 coiled-coil domain containing 6
CCND1 cyclin D1
CDC25A cell division cycle 25A
CDC25B cell division cycle 25B
CDC25C cell division cycle 25C
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CFL1 cofilin 1 (non-muscle)
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHAT choline O-acetyltransferase
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CHRM2 cholinergic receptor, muscarinic 2
CHUK conserved helix-loop-helix ubiquitous kinase
CLCN3 chloride channel, voltage-sensitive 3
COIL coilin
CREB1 cAMP responsive element binding protein 1
CRYAB crystallin, alpha B
CTBP1 C-terminal binding protein 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTTN cortactin
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
DAPK1 death-associated protein kinase 1
DRD1 dopamine receptor D1
DRD4 dopamine receptor D4
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
EGFR epidermal growth factor receptor
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
EIF4E eukaryotic translation initiation factor 4E
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ELAVL1 ELAV like RNA binding protein 1
ELK1 ELK1, member of ETS oncogene family
EP300 E1A binding protein p300
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERN1 endoplasmic reticulum to nucleus signaling 1
ESR1 estrogen receptor 1
F5 coagulation factor V (proaccelerin, labile factor)
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOXO1 forkhead box O1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GAP43 growth associated protein 43
GATA1 GATA binding protein 1 (globin transcription factor 1)
GATA4 GATA binding protein 4
GFPT1 glutamine--fructose-6-phosphate transaminase 1
GJA1 gap junction protein, alpha 1, 43kDa
GJA4 gap junction protein, alpha 4, 37kDa
GLRA3 glycine receptor, alpha 3
GNG12 guanine nucleotide binding protein (G protein), gamma 12
GOLGA2 golgin A2
GP1BB glycoprotein Ib (platelet), beta polypeptide
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIA2 glutamate receptor, ionotropic, AMPA 2
GRIA3 glutamate receptor, ionotropic, AMPA 3
GRIA4 glutamate receptor, ionotropic, AMPA 4
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRK1 G protein-coupled receptor kinase 1
GRK7 G protein-coupled receptor kinase 7
GRM1 glutamate receptor, metabotropic 1
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
GYS1 glycogen synthase 1 (muscle)
H2AFX H2A histone family, member X
H3F3A H3 histone, family 3A
H3F3B H3 histone, family 3B (H3.3B)
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HIST1H2BB histone cluster 1, H2bb
HIST1H3A histone cluster 1, H3a
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HSPB1 heat shock 27kDa protein 1
HSPB6 heat shock protein, alpha-crystallin-related, B6
HTRA2 HtrA serine peptidase 2
ICAM1 intercellular adhesion molecule 1
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
INSR insulin receptor
IRF3 interferon regulatory factor 3
IRF7 interferon regulatory factor 7
IRS1 insulin receptor substrate 1
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITGB4 integrin, beta 4
JAK2 Janus kinase 2
JUN jun proto-oncogene
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KCNE3 potassium channel, voltage gated subfamily E regulatory beta subunit 3
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KDR kinase insert domain receptor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KRT18 keratin 18, type I
KRT8 keratin 8, type II
L1CAM L1 cell adhesion molecule
LASP1 LIM and SH3 protein 1
LCK LCK proto-oncogene, Src family tyrosine kinase
LHX3 LIM homeobox 3
LIMK1 LIM domain kinase 1
LIMK2 LIM domain kinase 2
LIPE lipase, hormone-sensitive
LRP6 low density lipoprotein receptor-related protein 6
LTB4R leukotriene B4 receptor
LY96 lymphocyte antigen 96
LYN LYN proto-oncogene, Src family tyrosine kinase
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K6 mitogen-activated protein kinase kinase 6
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAPK1 mitogen-activated protein kinase 1
MAPK12 mitogen-activated protein kinase 12
MAPK14 mitogen-activated protein kinase 14
MAPK15 mitogen-activated protein kinase 15
MAPK3 mitogen-activated protein kinase 3
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MARCKS myristoylated alanine-rich protein kinase C substrate
MCC mutated in colorectal cancers
MCL1 myeloid cell leukemia 1
MCM3 minichromosome maintenance complex component 3
MCTS1 malignant T cell amplified sequence 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MET MET proto-oncogene, receptor tyrosine kinase
MITF microphthalmia-associated transcription factor
MKNK1 MAP kinase interacting serine/threonine kinase 1
MPL MPL proto-oncogene, thrombopoietin receptor
MSN moesin
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYF6 myogenic factor 6 (herculin)
MYOD1 myogenic differentiation 1
NBN nibrin
NCF1 neutrophil cytosolic factor 1
NEFL neurofilament, light polypeptide
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NPR1 natriuretic peptide receptor 1
NR2C1 nuclear receptor subfamily 2, group C, member 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRIP1 nuclear receptor interacting protein 1
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
OPRD1 opioid receptor, delta 1
OPRK1 opioid receptor, kappa 1
OPRM1 opioid receptor, mu 1
OXSR1 oxidative stress responsive 1
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PDE6G phosphodiesterase 6G, cGMP-specific, rod, gamma
PDE6H phosphodiesterase 6H, cGMP-specific, cone, gamma
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDPK1 3-phosphoinositide dependent protein kinase 1
PEA15 phosphoprotein enriched in astrocytes 15
PECAM1 platelet/endothelial cell adhesion molecule 1
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PKLR pyruvate kinase, liver and RBC
PKN1 protein kinase N1
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLIN1 perilipin 1
PLN phospholamban
PLSCR1 phospholipid scramblase 1
PNPT1 polyribonucleotide nucleotidyltransferase 1
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PPP1R14A protein phosphatase 1, regulatory (inhibitor) subunit 14A
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKCE protein kinase C, epsilon
PRKCG protein kinase C, gamma
PRKCZ protein kinase C, zeta
PRKD1 protein kinase D1
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator
PROS1 protein S (alpha)
PTEN phosphatase and tensin homolog
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTPRA protein tyrosine phosphatase, receptor type, A
PXN paxillin
RAD51 RAD51 recombinase
RAD52 RAD52 homolog (S. cerevisiae)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RB1 retinoblastoma 1
RBM4 RNA binding motif protein 4
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RGS9 regulator of G-protein signaling 9
RHO rhodopsin
RHOA ras homolog family member A
RIPK2 receptor-interacting serine-threonine kinase 2
RPA2 replication protein A2, 32kDa
RPS6 ribosomal protein S6
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RUNX1 runt-related transcription factor 1
RXRA retinoid X receptor, alpha
RYR1 ryanodine receptor 1 (skeletal)
S100A11 S100 calcium binding protein A11
SCN5A sodium channel, voltage gated, type V alpha subunit
SCNN1B sodium channel, non voltage gated 1 beta subunit
SH3BP4 SH3-domain binding protein 4
SIRT1 sirtuin 1
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SLC14A2 solute carrier family 14 (urea transporter), member 2
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SLN sarcolipin
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMC1A structural maintenance of chromosomes 1A
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
SOX9 SRY (sex determining region Y)-box 9
SPHK1 sphingosine kinase 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SSTR2 somatostatin receptor 2
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT2 signal transducer and activator of transcription 2, 113kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STK11 serine/threonine kinase 11
STK39 serine threonine kinase 39
STMN2 stathmin 2
STXBP3 syntaxin binding protein 3
SUB1 SUB1 homolog (S. cerevisiae)
SYN1 synapsin I
SYNGAP1 synaptic Ras GTPase activating protein 1
TACC3 transforming, acidic coiled-coil containing protein 3
TBC1D4 TBC1 domain family, member 4
TERT telomerase reverse transcriptase
TH tyrosine hydroxylase
THOP1 thimet oligopeptidase 1
TLX1 T-cell leukemia homeobox 1
TNNI3 troponin I type 3 (cardiac)
TOPBP1 topoisomerase (DNA) II binding protein 1
TP53 tumor protein p53
TP63 tumor protein p63
TRHR thyrotropin-releasing hormone receptor
TRIM28 tripartite motif containing 28
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TRPV4 transient receptor potential cation channel, subfamily V, member 4
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7
VASP vasodilator-stimulated phosphoprotein
VCL vinculin
VIM vimentin
WHSC1 Wolf-Hirschhorn syndrome candidate 1
WNK1 WNK lysine deficient protein kinase 1
WWOX WW domain containing oxidoreductase
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
YAP1 Yes-associated protein 1
YBX1 Y box binding protein 1