extreme Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

116 genes co-occuring with the biological term extreme in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACE angiotensin I converting enzyme
ACKR1 atypical chemokine receptor 1 (Duffy blood group)
ADIPOQ adiponectin, C1Q and collagen domain containing
ADIPOR1 adiponectin receptor 1
ADIPOR2 adiponectin receptor 2
AGTR1 angiotensin II receptor, type 1
ALX1 ALX homeobox 1
AMH anti-Mullerian hormone
APLP1 amyloid beta (A4) precursor-like protein 1
APLP2 amyloid beta (A4) precursor-like protein 2
APOA1 apolipoprotein A-I
APOA5 apolipoprotein A-V
APOE apolipoprotein E
ATM ATM serine/threonine kinase
BCR breakpoint cluster region
BNC2 basonuclin 2
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BRCA2 breast cancer 2, early onset
CCK cholecystokinin
CCL8 chemokine (C-C motif) ligand 8
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CNR1 cannabinoid receptor 1 (brain)
CPSF3L cleavage and polyadenylation specific factor 3-like
CPT1B carnitine palmitoyltransferase 1B (muscle)
CREB3L3 cAMP responsive element binding protein 3-like 3
CUL1 cullin 1
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DCTN4 dynactin 4 (p62)
DLK1 delta-like 1 homolog (Drosophila)
DNM1L dynamin 1-like
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
ESR1 estrogen receptor 1
FAAH fatty acid amide hydrolase
FANCD2 Fanconi anemia, complementation group D2
FANCE Fanconi anemia, complementation group E
FGF10 fibroblast growth factor 10
FTO fat mass and obesity associated
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GCK glucokinase (hexokinase 4)
GRM1 glutamate receptor, metabotropic 1
HLA-B major histocompatibility complex, class I, B
IGF1 insulin-like growth factor 1 (somatomedin C)
IL6 interleukin 6
INS insulin
INTS9 integrator complex subunit 9
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KLK3 kallikrein-related peptidase 3
LEP leptin
LEPR leptin receptor
LIG4 ligase IV, DNA, ATP-dependent
LMNA lamin A/C
LPA lipoprotein, Lp(a)
LPL lipoprotein lipase
LRRK2 leucine-rich repeat kinase 2
MAPT microtubule-associated protein tau
MC4R melanocortin 4 receptor
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MFRP membrane frizzled-related protein
MSH2 mutS homolog 2
MTTP microsomal triglyceride transfer protein
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
NF1 neurofibromin 1
NLRP12 NLR family, pyrin domain containing 12
NPPB natriuretic peptide B
NPY neuropeptide Y
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR5A1 nuclear receptor subfamily 5, group A, member 1
NRG1 neuregulin 1
OFD1 oral-facial-digital syndrome 1
OXT oxytocin/neurophysin I prepropeptide
OXTR oxytocin receptor
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
P4HB prolyl 4-hydroxylase, beta polypeptide
PAX6 paired box 6
PER1 period circadian clock 1
PGM1 phosphoglucomutase 1
PKN2 protein kinase N2
PON1 paraoxonase 1
POU5F1 POU class 5 homeobox 1
PPARA peroxisome proliferator-activated receptor alpha
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PTEN phosphatase and tensin homolog
RAD52 RAD52 homolog (S. cerevisiae)
RB1 retinoblastoma 1
RBX1 ring-box 1, E3 ubiquitin protein ligase
RHOA ras homolog family member A
RNH1 ribonuclease/angiogenin inhibitor 1
RYR1 ryanodine receptor 1 (skeletal)
SALL1 spalt-like transcription factor 1
SCN4A sodium channel, voltage gated, type IV alpha subunit
SCN4B sodium channel, voltage gated, type IV beta subunit
SCN5A sodium channel, voltage gated, type V alpha subunit
SCN9A sodium channel, voltage gated, type IX alpha subunit
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SOCS3 suppressor of cytokine signaling 3
SOD1 superoxide dismutase 1, soluble
STIM1 stromal interaction molecule 1
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic)
TMEM43 transmembrane protein 43
TNF tumor necrosis factor
TP53 tumor protein p53
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
VKORC1 vitamin K epoxide reductase complex, subunit 1
WAS Wiskott-Aldrich syndrome
XCL1 chemokine (C motif) ligand 1
XPO1 exportin 1