eye development Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight. (Gene Ontology, GO_0001654)
External Link http://amigo.geneontology.org/amigo/term/GO:0001654
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Genes

59 genes participating in the eye development biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ABCB5 ATP-binding cassette, sub-family B (MDR/TAP), member 5
ADAMTS18 ADAM metallopeptidase with thrombospondin type 1 motif, 18
ATF6 activating transcription factor 6
BLOC1S3 biogenesis of lysosomal organelles complex-1, subunit 3
BMPR1B bone morphogenetic protein receptor, type IB
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CEP290 centrosomal protein 290kDa
CHRDL1 chordin-like 1
COL5A1 collagen, type V, alpha 1
COL5A2 collagen, type V, alpha 2
CPAMD8 C3 and PZP-like, alpha-2-macroglobulin domain containing 8
CRYBA4 crystallin, beta A4
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
FBN1 fibrillin 1
FBN2 fibrillin 2
FOXC1 forkhead box C1
FOXE3 forkhead box E3
FREM2 FRAS1 related extracellular matrix protein 2
FZD5 frizzled class receptor 5
GDF3 growth differentiation factor 3
HES5 hes family bHLH transcription factor 5
HIPK1 homeodomain interacting protein kinase 1
HIPK2 homeodomain interacting protein kinase 2
MAB21L1 mab-21-like 1 (C. elegans)
MAB21L2 mab-21-like 2 (C. elegans)
MEIS1 Meis homeobox 1
MEIS2 Meis homeobox 2
MEIS3 Meis homeobox 3
NEUROD4 neuronal differentiation 4
NIPBL Nipped-B homolog (Drosophila)
PAX2 paired box 2
PAX6 paired box 6
PBX1 pre-B-cell leukemia homeobox 1
PBX2 pre-B-cell leukemia homeobox 2
PBX3 pre-B-cell leukemia homeobox 3
PBX4 pre-B-cell leukemia homeobox 4
PITX2 paired-like homeodomain 2
PRSS56 protease, serine, 56
RAB18 RAB18, member RAS oncogene family
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic)
RBP4 retinol binding protein 4, plasma
RSC1A1 regulatory solute carrier protein, family 1, member 1
SALL2 spalt-like transcription factor 2
SCO2 SCO2 cytochrome c oxidase assembly protein
SH3PXD2B SH3 and PX domains 2B
SHROOM2 shroom family member 2
SIPA1L3 signal-induced proliferation-associated 1 like 3
SIX3 SIX homeobox 3
SIX6 SIX homeobox 6
SKI SKI proto-oncogene
SLC39A5 solute carrier family 39 (zinc transporter), member 5
SMG9 SMG9 nonsense mediated mRNA decay factor
SMOC1 SPARC related modular calcium binding 1
SOX2 SRY (sex determining region Y)-box 2
STRA6 stimulated by retinoic acid 6
TGFB2 transforming growth factor, beta 2
TSKU tsukushi, small leucine rich proteoglycan
WT1 Wilms tumor 1
ZDHHC16 zinc finger, DHHC-type containing 16