eyelid disease Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description An adnexa disease that is located_in the eyelid. (Human Disease Ontology, DOID_530)
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Genes

282 genes co-occuring with the disease eyelid disease in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
FOXL2 forkhead box L2 2.73564
CAMP cathelicidin antimicrobial peptide 2.17706
LAX1 lymphocyte transmembrane adaptor 1 2.13921
FOXP2 forkhead box P2 1.60636
MBD5 methyl-CpG binding domain protein 5 1.54318
THAP1 THAP domain containing, apoptosis associated protein 1 1.4149
LACRT lacritin 1.35812
DCXR dicarbonyl/L-xylulose reductase 1.32629
OMD osteomodulin 1.27039
EIF4E3 eukaryotic translation initiation factor 4E family member 3 1.23212
UBE3B ubiquitin protein ligase E3B 1.16735
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12 1.16435
SCARF2 scavenger receptor class F, member 2 1.09209
GPR27 G protein-coupled receptor 27 1.09125
DOCK8 dedicator of cytokinesis 8 1.08915
TGM1 transglutaminase 1 1.06774
COPB2 coatomer protein complex, subunit beta 2 (beta prime) 1.0168
GMEB1 glucocorticoid modulatory element binding protein 1 0.994861
LTF lactotransferrin 0.97296
ALS2CL ALS2 C-terminal like 0.968341
ZMIZ2 zinc finger, MIZ-type containing 2 0.959542
LIPA lipase A, lysosomal acid, cholesterol esterase 0.929173
MECR mitochondrial trans-2-enoyl-CoA reductase 0.908142
TOR1A torsin family 1, member A (torsin A) 0.890898
GDF9 growth differentiation factor 9 0.874509
CXXC5 CXXC finger protein 5 0.847078
SRCIN1 SRC kinase signaling inhibitor 1 0.844621
GCH1 GTP cyclohydrolase 1 0.839296
MRPS22 mitochondrial ribosomal protein S22 0.833148
SOX14 SRY (sex determining region Y)-box 14 0.799923
NR2C1 nuclear receptor subfamily 2, group C, member 1 0.799103
SHE Src homology 2 domain containing E 0.789262
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) 0.788442
LYZ lysozyme 0.783526
AADAC arylacetamide deacetylase 0.745172
CD79A CD79a molecule, immunoglobulin-associated alpha 0.709975
MYOM1 myomesin 1 0.707157
DRD5 dopamine receptor D5 0.706351
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 0.697109
CXXC4 CXXC finger protein 4 0.693098
WIPI1 WD repeat domain, phosphoinositide interacting 1 0.682294
KRT38 keratin 38, type I 0.680697
ALX3 ALX homeobox 3 0.6791
ZFYVE1 zinc finger, FYVE domain containing 1 0.670732
LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 0.670333
CDIP1 cell death-inducing p53 target 1 0.661594
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type 0.653276
FOXD3 forkhead box D3 0.651298
KAT6B K(lysine) acetyltransferase 6B 0.63907
ZIC4 Zic family member 4 0.636708
NOTCH1 notch 1 0.636708
CD4 CD4 molecule 0.624535
BCO1 beta-carotene oxygenase 1 0.623359
AIRE autoimmune regulator 0.621008
SON SON DNA binding protein 0.616312
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae) 0.614747
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 0.606543
CYP4V2 cytochrome P450, family 4, subfamily V, polypeptide 2 0.593285
PPP1R3C protein phosphatase 1, regulatory subunit 3C 0.590169
FSHR follicle stimulating hormone receptor 0.578883
MED12 mediator complex subunit 12 0.572273
PAX6 paired box 6 0.564889
ARHGEF19 Rho guanine nucleotide exchange factor (GEF) 19 0.564889
NIPBL Nipped-B homolog (Drosophila) 0.562169
RP2 retinitis pigmentosa 2 (X-linked recessive) 0.547032
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa 0.543155
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2 0.541605
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 0.521888
RP9 retinitis pigmentosa 9 (autosomal dominant) 0.518805
TBX20 T-box 20 0.516879
ZIC1 Zic family member 1 0.503058
FOXP1 forkhead box P1 0.497321
DDT D-dopachrome tautomerase 0.495029
BTD biotinidase 0.493885
RFXANK regulatory factor X-associated ankyrin-containing protein 0.489691
AFG3L2 AFG3-like AAA ATPase 2 0.486266
UROS uroporphyrinogen III synthase 0.485125
AADAT aminoadipate aminotransferase 0.476393
KIAA1109 KIAA1109 0.475634
PLXNA1 plexin A1 0.470711
CA3 carbonic anhydrase III 0.460129
ABHD5 abhydrolase domain containing 5 0.456732
CCBL1 cysteine conjugate-beta lyase, cytoplasmic 0.445805
MMP23B matrix metallopeptidase 23B 0.442418
CRYAA crystallin, alpha A 0.440914
CP ceruloplasmin (ferroxidase) 0.435651
GJB4 gap junction protein, beta 4, 30.3kDa 0.434148
BCL9 B-cell CLL/lymphoma 9 0.429642
CADM1 cell adhesion molecule 1 0.42814
GPR148 G protein-coupled receptor 148 0.420266
CMA1 chymase 1, mast cell 0.416521
ZFPM2 zinc finger protein, FOG family member 2 0.410161
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa 0.407172
TWIST2 twist family bHLH transcription factor 2 0.407172
PKD2L1 polycystic kidney disease 2-like 1 0.406798
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit 0.384822
PIAS1 protein inhibitor of activated STAT, 1 0.379256
SMC1A structural maintenance of chromosomes 1A 0.377773
PRCD progressive rod-cone degeneration 0.376661
OXA1L oxidase (cytochrome c) assembly 1-like 0.37592
OR10T2 olfactory receptor, family 10, subfamily T, member 2 0.371847
ALX4 ALX homeobox 4 0.369997
LTBP3 latent transforming growth factor beta binding protein 3 0.351923
DYNLRB1 dynein, light chain, roadblock-type 1 0.350084
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.328105
HPSE2 heparanase 2 (inactive) 0.322273
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) 0.321909
LTBP2 latent transforming growth factor beta binding protein 2 0.316456
ACKR1 atypical chemokine receptor 1 (Duffy blood group) 0.309928
PLCH2 phospholipase C, eta 2 0.308118
GJB6 gap junction protein, beta 6, 30kDa 0.30631
ACRV1 acrosomal vesicle protein 1 0.304503
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa 0.294053
MMP7 matrix metallopeptidase 7 0.291539
FLAD1 flavin adenine dinucleotide synthetase 1 0.28616
GSN gelsolin 0.284728
PTER phosphotriesterase related 0.27794
HEYL hes-related family bHLH transcription factor with YRPW motif-like 0.274021
IL33R interleukin 33 receptor 0.273664
CCL15 chemokine (C-C motif) ligand 15 0.271886
LCK LCK proto-oncogene, Src family tyrosine kinase 0.271886
PSIP1 PC4 and SFRS1 interacting protein 1 0.266203
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.263014
FOXE1 forkhead box E1 0.26266
KDM6A lysine (K)-specific demethylase 6A 0.260184
CHST14 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14 0.259124
ADAR adenosine deaminase, RNA-specific 0.257711
EHF ets homologous factor 0.253831
KLF5 Kruppel-like factor 5 (intestinal) 0.249608
TOB1 transducer of ERBB2, 1 0.249608
RNASE3 ribonuclease, RNase A family, 3 0.246799
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 0.244345
MNT MAX network transcriptional repressor 0.242245
MMP9 matrix metallopeptidase 9 0.242245
GJB3 gap junction protein, beta 3, 31kDa 0.239799
TTR transthyretin 0.23945
KMT2B lysine (K)-specific methyltransferase 2B 0.238752
PMM2 phosphomannomutase 2 0.232142
RBP1 retinol binding protein 1, cellular 0.230755
EGFR epidermal growth factor receptor 0.230063
FBLIM1 filamin binding LIM protein 1 0.227988
STAB2 stabilin 2 0.226607
PROK2 prokineticin 2 0.220766
VSX1 visual system homeobox 1 0.21974
ZNF77 zinc finger protein 77 0.21974
ZAK sterile alpha motif and leucine zipper containing kinase AZK 0.213283
MRPL49 mitochondrial ribosomal protein L49 0.213283
SEPT9 septin 9 0.212271
CCL4L2 chemokine (C-C motif) ligand 4-like 2 0.209583
CST4 cystatin S 0.209583
GJA4 gap junction protein, alpha 4, 37kDa 0.205254
CCL4L1 chemokine (C-C motif) ligand 4-like 1 0.203275
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.198709
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 0.196139
SHOX short stature homeobox 0.195501
PER2 period circadian clock 2 0.192971
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 0.192031
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.191719
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.191097
BBS1 Bardet-Biedl syndrome 1 0.190476
PANK2 pantothenate kinase 2 0.189859
CCL13 chemokine (C-C motif) ligand 13 0.187719
FOXC2 forkhead box C2 0.18621
CA2 carbonic anhydrase II 0.18621
FLNA filamin A, alpha 0.18591
FPR1 formyl peptide receptor 1 0.181798
OR10R2 olfactory receptor, family 10, subfamily R, member 2 0.180367
CLCN1 chloride channel, voltage-sensitive 1 0.178682
DAND5 DAN domain family member 5, BMP antagonist 0.178682
EDA ectodysplasin A 0.173571
TOX thymocyte selection-associated high mobility group box 0.173057
CHD7 chromodomain helicase DNA binding protein 7 0.166544
ST14 suppression of tumorigenicity 14 (colon carcinoma) 0.165874
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 0.163938
IFNAR2 interferon (alpha, beta and omega) receptor 2 0.160948
RECQL4 RecQ protein-like 4 0.158434
TIMP2 TIMP metallopeptidase inhibitor 2 0.129622
MMP3 matrix metallopeptidase 3 0.12859
ICAM1 intercellular adhesion molecule 1 0.127957
MMP2 matrix metallopeptidase 2 0.124983
CLDN3 claudin 3 0.122931
IL6R interleukin 6 receptor 0.122299
NDUFS7 NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) 0.118734
TSPO translocator protein (18kDa) 0.115904
CBS cystathionine-beta-synthase 0.114787
PPT1 palmitoyl-protein thioesterase 1 0.112706
CSN1S1 casein alpha s1 0.109077
DSG3 desmoglein 3 0.108087
PNMA2 paraneoplastic Ma antigen 2 0.107982
CCL20 chemokine (C-C motif) ligand 20 0.107648
NELFCD negative elongation factor complex member C/D 0.10528
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.105248
CXCL8 chemokine (C-X-C motif) ligand 8 0.104292
FYN FYN proto-oncogene, Src family tyrosine kinase 0.10088
CXCL9 chemokine (C-X-C motif) ligand 9 0.099618
CTSG cathepsin G 0.09951
TF transferrin 0.096121
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.096064
C5AR1 complement component 5a receptor 1 0.094167
CD34 CD34 molecule 0.092483
DAXX death-domain associated protein 0.091473
SAA1 serum amyloid A1 0.090557
MMP1 matrix metallopeptidase 1 0.089606
LOR loricrin 0.086655
FOXC1 forkhead box C1 0.086633
PABPN1 poly(A) binding protein, nuclear 1 0.086484
NF1 neurofibromin 1 0.086033
PITX2 paired-like homeodomain 2 0.085168
PPP1R12A protein phosphatase 1, regulatory subunit 12A 0.084995
PRSS21 protease, serine, 21 (testisin) 0.084973
PIDD1 p53-induced death domain protein 1 0.082578
DNAH8 dynein, axonemal, heavy chain 8 0.082422
CYGB cytoglobin 0.080635
CD59 CD59 molecule, complement regulatory protein 0.079415
DCT dopachrome tautomerase 0.07912
HLA-C major histocompatibility complex, class I, C 0.079075
ATM ATM serine/threonine kinase 0.078644
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 0.078187
SDC2 syndecan 2 0.077935
HMOX2 heme oxygenase 2 0.077477
BANF1 barrier to autointegration factor 1 0.077408
TLR8 toll-like receptor 8 0.077111
SMO smoothened, frizzled class receptor 0.07658
SRY sex determining region Y 0.076534
FBN2 fibrillin 2 0.076003
NUP98 nucleoporin 98kDa 0.075518
IGFBP5 insulin-like growth factor binding protein 5 0.075426
ICK intestinal cell (MAK-like) kinase 0.074542
GALT galactose-1-phosphate uridylyltransferase 0.074472
TNS1 tensin 1 0.074472
MRAP melanocortin 2 receptor accessory protein 0.074262
LMNA lamin A/C 0.074053
PLA2G10 phospholipase A2, group X 0.07403
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.073563
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) 0.07354
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 0.072931
LATS1 large tumor suppressor kinase 1 0.072252
COL7A1 collagen, type VII, alpha 1 0.072158
IL4 interleukin 4 0.071569
SRSF1 serine/arginine-rich splicing factor 1 0.071428
ATR ATR serine/threonine kinase 0.071216
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 0.071192
PML promyelocytic leukemia 0.071121
CD68 CD68 molecule 0.07098
UBE3A ubiquitin protein ligase E3A 0.070863
CD6 CD6 molecule 0.070721
FST follistatin 0.070273
C1QBP complement component 1, q subcomponent binding protein 0.070202
COL17A1 collagen, type XVII, alpha 1 0.070155
PLA2G1B phospholipase A2, group IB (pancreas) 0.069184
MUC4 mucin 4, cell surface associated 0.069042
CREM cAMP responsive element modulator 0.068093
PTPRC protein tyrosine phosphatase, receptor type, C 0.067784
MCM8 minichromosome maintenance complex component 8 0.067547
MMP8 matrix metallopeptidase 8 0.067452
RBP4 retinol binding protein 4, plasma 0.067405
IFNA2 interferon, alpha 2 0.067357
PIP prolactin-induced protein 0.067357
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.06731
MUC1 mucin 1, cell surface associated 0.067191
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.067096
POLG polymerase (DNA directed), gamma 0.067072
IL1B interleukin 1, beta 0.067048
GOLPH3 golgi phosphoprotein 3 (coat-protein) 0.066834
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.065834
TACR1 tachykinin receptor 1 0.06531
STAT4 signal transducer and activator of transcription 4 0.065286
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 0.065143
HPSE heparanase 0.064428
KLF4 Kruppel-like factor 4 (gut) 0.064332
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.064166
PAX5 paired box 5 0.064166
SDC1 syndecan 1 0.06388
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.063737
CALR calreticulin 0.063522
FN1 fibronectin 1 0.062854
SOX9 SRY (sex determining region Y)-box 9 0.062663
IL2RA interleukin 2 receptor, alpha 0.06252
CCL4 chemokine (C-C motif) ligand 4 0.062377
HLA-B major histocompatibility complex, class I, B 0.062353
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.06221
PAX3 paired box 3 0.062139