failed Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

317 genes co-occuring with the biological term failed in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACE angiotensin I converting enzyme
ACOT13 acyl-CoA thioesterase 13
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
ADIPOQ adiponectin, C1Q and collagen domain containing
ADRM1 adhesion regulating molecule 1
AGER advanced glycosylation end product-specific receptor
AGO2 argonaute RISC catalytic component 2
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ALK anaplastic lymphoma receptor tyrosine kinase
ALOX12 arachidonate 12-lipoxygenase
ALOX15 arachidonate 15-lipoxygenase
ALOX5 arachidonate 5-lipoxygenase
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ANGPT1 angiopoietin 1
ANGPT2 angiopoietin 2
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANXA11 annexin A11
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
AQP4 aquaporin 4
AR androgen receptor
ARHGAP6 Rho GTPase activating protein 6
ASPN asporin
ASPRV1 aspartic peptidase, retroviral-like 1
ATM ATM serine/threonine kinase
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
AURKA aurora kinase A
AVP arginine vasopressin
BAX BCL2-associated X protein
BCR breakpoint cluster region
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase)
CALHM1 calcium homeostasis modulator 1
CALHM2 calcium homeostasis modulator 2
CALHM3 calcium homeostasis modulator 3
CAMP cathelicidin antimicrobial peptide
CAPN10 calpain 10
CARD11 caspase recruitment domain family, member 11
CARTPT CART prepropeptide
CASP3 caspase 3, apoptosis-related cysteine peptidase
CAT catalase
CCL2 chemokine (C-C motif) ligand 2
CCNA1 cyclin A1
CCNB1 cyclin B1
CCNB2 cyclin B2
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD180 CD180 molecule
CD274 CD274 molecule
CD79B CD79b molecule, immunoglobulin-associated beta
CD86 CD86 molecule
CDC25A cell division cycle 25A
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CLEC4M C-type lectin domain family 4, member M
CLOCK clock circadian regulator
COL1A1 collagen, type I, alpha 1
COMT catechol-O-methyltransferase
CTH cystathionine gamma-lyase
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSC cathepsin C
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR2 chemokine (C-X-C motif) receptor 2
CYBA cytochrome b-245, alpha polypeptide
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DACH1 dachshund family transcription factor 1
DAOA D-amino acid oxidase activator
DAOA-AS1 DAOA antisense RNA 1
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DDR1 discoidin domain receptor tyrosine kinase 1
DFFA DNA fragmentation factor, 45kDa, alpha polypeptide
DFNB59 deafness, autosomal recessive 59
DIAPH3 diaphanous-related formin 3
DRD4 dopamine receptor D4
DSG1 desmoglein 1
EDN1 endothelin 1
EDNRA endothelin receptor type A
EDNRB endothelin receptor type B
EGF epidermal growth factor
EGFR epidermal growth factor receptor
ELN elastin
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB4 erb-b2 receptor tyrosine kinase 4
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
F2R coagulation factor II (thrombin) receptor
F8 coagulation factor VIII, procoagulant component
FABP3 fatty acid binding protein 3, muscle and heart
FADD Fas (TNFRSF6)-associated via death domain
FBN1 fibrillin 1
FGF16 fibroblast growth factor 16
FGF23 fibroblast growth factor 23
FGFR4 fibroblast growth factor receptor 4
FLOT1 flotillin 1
FLT1 fms-related tyrosine kinase 1
FLT4 fms-related tyrosine kinase 4
FLVCR1 feline leukemia virus subgroup C cellular receptor 1
FN1 fibronectin 1
FOXP3 forkhead box P3
FRK fyn-related Src family tyrosine kinase
FSHR follicle stimulating hormone receptor
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3
GH1 growth hormone 1
GHRL ghrelin/obestatin prepropeptide
GJB1 gap junction protein, beta 1, 32kDa
GJB2 gap junction protein, beta 2, 26kDa
GNAS GNAS complex locus
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GRIA1 glutamate receptor, ionotropic, AMPA 1
HABP2 hyaluronan binding protein 2
HEPACAM hepatic and glial cell adhesion molecule
HFE hemochromatosis
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-B major histocompatibility complex, class I, B
HMOX1 heme oxygenase 1
HMOX2 heme oxygenase 2
HR hair growth associated
HRAS Harvey rat sarcoma viral oncogene homolog
IDDM8 insulin-dependent diabetes mellitus 8
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IFNL1 interferon, lambda 1
IFNL3 interferon, lambda 3
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGFBP4 insulin-like growth factor binding protein 4
IGHD3-3 immunoglobulin heavy diversity 3-3
IL10 interleukin 10
IL12B interleukin 12B
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL4 interleukin 4
IL6 interleukin 6
INS insulin
IRF3 interferon regulatory factor 3
ITPKC inositol-trisphosphate 3-kinase C
JAK2 Janus kinase 2
JAK3 Janus kinase 3
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KCNK5 potassium channel, two pore domain subfamily K, member 5
KCTD15 potassium channel tetramerization domain containing 15
KDR kinase insert domain receptor
KLF12 Kruppel-like factor 12
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT14 keratin 14, type I
KRT5 keratin 5, type II
LAMP1 lysosomal-associated membrane protein 1
LAMP2 lysosomal-associated membrane protein 2
LARS leucyl-tRNA synthetase
LHCGR luteinizing hormone/choriogonadotropin receptor
LTA4H leukotriene A4 hydrolase
LTC4S leukotriene C4 synthase
MBL2 mannose-binding lectin (protein C) 2, soluble
MIR122 microRNA 122
MIR137 microRNA 137
MIR146A microRNA 146a
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MRC1 mannose receptor, C type 1
MRPL19 mitochondrial ribosomal protein L19
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MUC1 mucin 1, cell surface associated
MUC16 mucin 16, cell surface associated
MYD88 myeloid differentiation primary response 88
NDE1 nudE neurodevelopment protein 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NHEJ1 nonhomologous end-joining factor 1
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1
NOD2 nucleotide-binding oligomerization domain containing 2
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
NPPB natriuretic peptide B
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUAK2 NUAK family, SNF1-like kinase, 2
NUP62 nucleoporin 62kDa
OXTR oxytocin receptor
PANX1 pannexin 1
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PCM1 pericentriolar material 1
PCSK1 proprotein convertase subtilisin/kexin type 1
PDPN podoplanin
PDZD8 PDZ domain containing 8
PGF placental growth factor
PICK1 protein interacting with PRKCA 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PKLR pyruvate kinase, liver and RBC
PLCZ1 phospholipase C, zeta 1
PLK1 polo-like kinase 1
PLXNA2 plexin A2
PMP22 peripheral myelin protein 22
POU2F1 POU class 2 homeobox 1
PRC1 protein regulator of cytokinesis 1
PREX1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
PRKCD protein kinase C, delta
PRM1 protamine 1
PRM2 protamine 2
PROCR protein C receptor, endothelial
PROS1 protein S (alpha)
PRRC2A proline-rich coiled-coil 2A
PRSS1 protease, serine, 1 (trypsin 1)
PSEN1 presenilin 1
PSIP1 PC4 and SFRS1 interacting protein 1
PTEN phosphatase and tensin homolog
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTN pleiotrophin
PTX3 pentraxin 3, long
RAB11A RAB11A, member RAS oncogene family
RB1 retinoblastoma 1
RECQL4 RecQ protein-like 4
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RETN resistin
RIPK2 receptor-interacting serine-threonine kinase 2
RIT2 Ras-like without CAAX 2
RRBP1 ribosome binding protein 1
RTN3 reticulon 3
RWDD3 RWD domain containing 3
SAT1 spermidine/spermine N1-acetyltransferase 1
SCG3 secretogranin III
SCG5 secretogranin V
SEC16B SEC16 homolog B (S. cerevisiae)
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SESN2 sestrin 2
SH2B1 SH2B adaptor protein 1
SLC19A1 solute carrier family 19 (folate transporter), member 1
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC25A19 solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SMAD3 SMAD family member 3
SMAD4 SMAD family member 4
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOD2 superoxide dismutase 2, mitochondrial
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
ST7 suppression of tumorigenicity 7
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STK11 serine/threonine kinase 11
STXBP1 syntaxin binding protein 1
STXBP3 syntaxin binding protein 3
TBX1 T-box 1
TBX21 T-box 21
TCF4 transcription factor 4
TECTA tectorin alpha
TGFB1 transforming growth factor, beta 1
TGM2 transglutaminase 2
TICAM1 toll-like receptor adaptor molecule 1
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TIMP3 TIMP metallopeptidase inhibitor 3
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TMEM173 transmembrane protein 173
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TP53 tumor protein p53
TP63 tumor protein p63
TPH2 tryptophan hydroxylase 2
TRAPPC2 trafficking protein particle complex 2
TRAPPC8 trafficking protein particle complex 8
TRAPPC9 trafficking protein particle complex 9
TYMP thymidine phosphorylase
UBB ubiquitin B
UBE2D1 ubiquitin-conjugating enzyme E2D 1
UBE3A ubiquitin protein ligase E3A
UCN urocortin
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae)
WIF1 WNT inhibitory factor 1
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
YAP1 Yes-associated protein 1
ZBTB3 zinc finger and BTB domain containing 3