failure of atrioventricular cushion closure Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description failure of the mounds of embryonic connective tissue that bulge into the fetal atrioventricular canal to fuse to form the valves between the right and left atrioventricular orifices (Mammalian Phenotype Ontology, MP_0000299)
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7 gene mutations causing the failure of atrioventricular cushion closure phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CYR61 cysteine-rich, angiogenic inducer, 61
NRG1 neuregulin 1
PITX2 paired-like homeodomain 2
PKD1 polycystic kidney disease 1 (autosomal dominant)
RXRA retinoid X receptor, alpha
TGFB2 transforming growth factor, beta 2
TLL1 tolloid-like 1