famotidine-1946 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the famotidine-1946 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABHD3 abhydrolase domain containing 3
ACLY ATP citrate lyase
ACVRL1 activin A receptor type II-like 1
ADAM12 ADAM metallopeptidase domain 12
ADORA1 adenosine A1 receptor
ANAPC2 anaphase promoting complex subunit 2
APOE apolipoprotein E
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARSJ arylsulfatase family, member J
ATG12 autophagy related 12
BCL9 B-cell CLL/lymphoma 9
BMP6 bone morphogenetic protein 6
BMPR1A bone morphogenetic protein receptor, type IA
C1ORF27 chromosome 1 open reading frame 27
C9ORF16 chromosome 9 open reading frame 16
CACTIN cactin, spliceosome C complex subunit
CHN2 chimerin 2
CIZ1 CDKN1A interacting zinc finger protein 1
CST4 cystatin S
CUEDC1 CUE domain containing 1
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
DHTKD1 dehydrogenase E1 and transketolase domain containing 1
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1
ENOSF1 enolase superfamily member 1
FAM172A family with sequence similarity 172, member A
GATAD1 GATA zinc finger domain containing 1
GEMIN4 gem (nuclear organelle) associated protein 4
GFER growth factor, augmenter of liver regeneration
GLI3 GLI family zinc finger 3
GMPR guanosine monophosphate reductase
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa
HFE hemochromatosis
HHEX hematopoietically expressed homeobox
HLA-G major histocompatibility complex, class I, G
HMOX2 heme oxygenase 2
HOXA10 homeobox A10
HOXC10 homeobox C10
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
ITSN1 intersectin 1 (SH3 domain protein)
KLF6 Kruppel-like factor 6
KLHL3 kelch-like family member 3
KRT17 keratin 17, type I
LPP LIM domain containing preferred translocation partner in lipoma
MBD2 methyl-CpG binding domain protein 2
MECP2 methyl CpG binding protein 2
MYCBP MYC binding protein
NCAM1 neural cell adhesion molecule 1
NPAT nuclear protein, ataxia-telangiectasia locus
NUDT2 nudix (nucleoside diphosphate linked moiety X)-type motif 2
NUP98 nucleoporin 98kDa
OLFM1 olfactomedin 1
PAIP1 poly(A) binding protein interacting protein 1
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PEX16 peroxisomal biogenesis factor 16
PIAS2 protein inhibitor of activated STAT, 2
PKP1 plakophilin 1
PLD1 phospholipase D1, phosphatidylcholine-specific
PLXND1 plexin D1
POLDIP3 polymerase (DNA-directed), delta interacting protein 3
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP1R10 protein phosphatase 1, regulatory subunit 10
PRKD2 protein kinase D2
PROSC proline synthetase co-transcribed homolog (bacterial)
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
PTPRF protein tyrosine phosphatase, receptor type, F
PTPRT protein tyrosine phosphatase, receptor type, T
PXN paxillin
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAD50 RAD50 homolog (S. cerevisiae)
RANBP3 RAN binding protein 3
RNF126 ring finger protein 126
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SH2D1A SH2 domain containing 1A
SLC22A14 solute carrier family 22, member 14
SLC30A1 solute carrier family 30 (zinc transporter), member 1
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TBRG4 transforming growth factor beta regulator 4
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
THTPA thiamine triphosphatase
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TNNI3 troponin I type 3 (cardiac)
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
UBAP2L ubiquitin associated protein 2-like
UBOX5 U-box domain containing 5
UFL1 UFM1-specific ligase 1
UNC45A unc-45 homolog A (C. elegans)
USP24 ubiquitin specific peptidase 24
WNT7A wingless-type MMTV integration site family, member 7A
YLPM1 YLP motif containing 1
ZNF609 zinc finger protein 609
ZNF764 zinc finger protein 764

decreased expression

Symbol Name
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
AES amino-terminal enhancer of split
APIP APAF1 interacting protein
ARGLU1 arginine and glutamate rich 1
ARHGAP5 Rho GTPase activating protein 5
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18
ASCC1 activating signal cointegrator 1 complex subunit 1
AVPI1 arginine vasopressin-induced 1
BNC2 basonuclin 2
C12ORF29 chromosome 12 open reading frame 29
C17ORF85 chromosome 17 open reading frame 85
C1ORF123 chromosome 1 open reading frame 123
C3ORF18 chromosome 3 open reading frame 18
CCDC68 coiled-coil domain containing 68
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CLGN calmegin
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CNTD2 cyclin N-terminal domain containing 2
CPOX coproporphyrinogen oxidase
CROT carnitine O-octanoyltransferase
CSGALNACT2 chondroitin sulfate N-acetylgalactosaminyltransferase 2
DENND1A DENN/MADD domain containing 1A
DENND1B DENN/MADD domain containing 1B
DHRS3 dehydrogenase/reductase (SDR family) member 3
DMTF1 cyclin D binding myb-like transcription factor 1
DPP3 dipeptidyl-peptidase 3
ELAVL2 ELAV like neuron-specific RNA binding protein 2
EPS8 epidermal growth factor receptor pathway substrate 8
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
FAF1 Fas (TNFRSF6) associated factor 1
FAM127B family with sequence similarity 127, member B
FAM188A family with sequence similarity 188, member A
FICD FIC domain containing
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GCHFR GTP cyclohydrolase I feedback regulator
GINS1 GINS complex subunit 1 (Psf1 homolog)
GPX2 glutathione peroxidase 2
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
IL15RA interleukin 15 receptor, alpha
IRF2BP1 interferon regulatory factor 2 binding protein 1
JOSD1 Josephin domain containing 1
JRKL JRK-like
KATNBL1 katanin p80 subunit B-like 1
KLHL12 kelch-like family member 12
KLHL21 kelch-like family member 21
KPNA4 karyopherin alpha 4 (importin alpha 3)
LONRF3 LON peptidase N-terminal domain and ring finger 3
LUC7L LUC7-like (S. cerevisiae)
MB myoglobin
MGMT O-6-methylguanine-DNA methyltransferase
NHEJ1 nonhomologous end-joining factor 1
NINJ1 ninjurin 1
NME3 NME/NM23 nucleoside diphosphate kinase 3
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NOD1 nucleotide-binding oligomerization domain containing 1
NSUN3 NOP2/Sun domain family, member 3
NUPL2 nucleoporin like 2
PARG poly (ADP-ribose) glycohydrolase
PDCD10 programmed cell death 10
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLCD1 phospholipase C, delta 1
PPCDC phosphopantothenoylcysteine decarboxylase
PPL periplakin
PTBP2 polypyrimidine tract binding protein 2
PYROXD1 pyridine nucleotide-disulphide oxidoreductase domain 1
RINT1 RAD50 interactor 1
RNF144A ring finger protein 144A
RPL23AP32 ribosomal protein L23a pseudogene 32
SAP30BP SAP30 binding protein
SHPK sedoheptulokinase
SLC25A38 solute carrier family 25, member 38
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SOAT1 sterol O-acyltransferase 1
SPAG16 sperm associated antigen 16
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STARD13 StAR-related lipid transfer (START) domain containing 13
STBD1 starch binding domain 1
STEAP3 STEAP family member 3, metalloreductase
STXBP1 syntaxin binding protein 1
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TRIM8 tripartite motif containing 8
TTC13 tetratricopeptide repeat domain 13
TTC4 tetratricopeptide repeat domain 4
UBXN2B UBX domain protein 2B
YIPF1 Yip1 domain family, member 1
ZBED1 zinc finger, BED-type containing 1
ZDHHC18 zinc finger, DHHC-type containing 18
ZFYVE16 zinc finger, FYVE domain containing 16
ZNF12 zinc finger protein 12
ZNF226 zinc finger protein 226
ZNF302 zinc finger protein 302
ZNF358 zinc finger protein 358
ZNF552 zinc finger protein 552
ZNF562 zinc finger protein 562
ZNF623 zinc finger protein 623
ZSCAN5A zinc finger and SCAN domain containing 5A