| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the famotidine-2029 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAN | aggrecan |
| ADAR | adenosine deaminase, RNA-specific |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| AMBRA1 | autophagy/beclin-1 regulator 1 |
| ANKRD55 | ankyrin repeat domain 55 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| AQP8 | aquaporin 8 |
| ARRB2 | arrestin, beta 2 |
| ATP5L | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G |
| B4GALT4 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 |
| BAX | BCL2-associated X protein |
| BICD2 | bicaudal D homolog 2 (Drosophila) |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) |
| C22ORF24 | chromosome 22 open reading frame 24 |
| C2CD2 | C2 calcium-dependent domain containing 2 |
| C3 | complement component 3 |
| C8ORF44 | chromosome 8 open reading frame 44 |
| CA12 | carbonic anhydrase XII |
| CANT1 | calcium activated nucleotidase 1 |
| CEP68 | centrosomal protein 68kDa |
| CETN1 | centrin, EF-hand protein, 1 |
| CHKA | choline kinase alpha |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLDN15 | claudin 15 |
| COL4A2 | collagen, type IV, alpha 2 |
| COMT | catechol-O-methyltransferase |
| DCTN4 | dynactin 4 (p62) |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) |
| ELMO2 | engulfment and cell motility 2 |
| ELOVL6 | ELOVL fatty acid elongase 6 |
| EPX | eosinophil peroxidase |
| FBXW11 | F-box and WD repeat domain containing 11 |
| FKBP9 | FK506 binding protein 9, 63 kDa |
| FNTB | farnesyltransferase, CAAX box, beta |
| GABPB1 | GA binding protein transcription factor, beta subunit 1 |
| GCAT | glycine C-acetyltransferase |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GLS | glutaminase |
| GMDS | GDP-mannose 4,6-dehydratase |
| HIST1H4J | histone cluster 1, H4j |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HR | hair growth associated |
| HTR1B | 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled |
| JRK | Jrk homolog (mouse) |
| KIFC1 | kinesin family member C1 |
| LDB1 | LIM domain binding 1 |
| LPP | LIM domain containing preferred translocation partner in lipoma |
| LRRK1 | leucine-rich repeat kinase 1 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MED27 | mediator complex subunit 27 |
| MYF6 | myogenic factor 6 (herculin) |
| N4BP1 | NEDD4 binding protein 1 |
| NUDT13 | nudix (nucleoside diphosphate linked moiety X)-type motif 13 |
| NUP160 | nucleoporin 160kDa |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PCIF1 | PDX1 C-terminal inhibiting factor 1 |
| PGC | progastricsin (pepsinogen C) |
| PIGA | phosphatidylinositol glycan anchor biosynthesis, class A |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PITPNA | phosphatidylinositol transfer protein, alpha |
| PLIN2 | perilipin 2 |
| POFUT1 | protein O-fucosyltransferase 1 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
| PPM1G | protein phosphatase, Mg2+/Mn2+ dependent, 1G |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PRDM14 | PR domain containing 14 |
| PSG9 | pregnancy specific beta-1-glycoprotein 9 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 |
| RBM48 | RNA binding motif protein 48 |
| REC8 | REC8 meiotic recombination protein |
| RECQL4 | RecQ protein-like 4 |
| RHOT2 | ras homolog family member T2 |
| SCCPDH | saccharopine dehydrogenase (putative) |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SETD4 | SET domain containing 4 |
| SIGLEC5 | sialic acid binding Ig-like lectin 5 |
| SIRT3 | sirtuin 3 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC31A1 | solute carrier family 31 (copper transporter), member 1 |
| SPPL2B | signal peptide peptidase like 2B |
| SPTLC1 | serine palmitoyltransferase, long chain base subunit 1 |
| SSSCA1 | Sjogren syndrome/scleroderma autoantigen 1 |
| TCF3 | transcription factor 3 |
| TERT | telomerase reverse transcriptase |
| TEX261 | testis expressed 261 |
| THTPA | thiamine triphosphatase |
| TMED2 | transmembrane emp24 domain trafficking protein 2 |
| TPM3 | tropomyosin 3 |
| TRABD | TraB domain containing |
| TRAF3IP3 | TRAF3 interacting protein 3 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 |
| WDR48 | WD repeat domain 48 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZNF335 | zinc finger protein 335 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| AACS | acetoacetyl-CoA synthetase |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 |
| AES | amino-terminal enhancer of split |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 |
| APH1B | APH1B gamma secretase subunit |
| ARG1 | arginase 1 |
| ASCC1 | activating signal cointegrator 1 complex subunit 1 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BCL10 | B-cell CLL/lymphoma 10 |
| BCL7C | B-cell CLL/lymphoma 7C |
| CARD9 | caspase recruitment domain family, member 9 |
| CCDC53 | coiled-coil domain containing 53 |
| CD248 | CD248 molecule, endosialin |
| CD2AP | CD2-associated protein |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
| CLP1 | cleavage and polyadenylation factor I subunit 1 |
| CLPB | ClpB homolog, mitochondrial AAA ATPase chaperonin |
| CMAS | cytidine monophosphate N-acetylneuraminic acid synthetase |
| COMMD10 | COMM domain containing 10 |
| CSF1R | colony stimulating factor 1 receptor |
| CTAGE9 | CTAGE family, member 9 |
| CTNNAL1 | catenin (cadherin-associated protein), alpha-like 1 |
| CYCS | cytochrome c, somatic |
| DEAF1 | DEAF1 transcription factor |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| DPF2 | D4, zinc and double PHD fingers family 2 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 |
| DUSP5 | dual specificity phosphatase 5 |
| DYNC1LI1 | dynein, cytoplasmic 1, light intermediate chain 1 |
| EDAR | ectodysplasin A receptor |
| EHD4 | EH-domain containing 4 |
| FAHD2A | fumarylacetoacetate hydrolase domain containing 2A |
| FAM111A | family with sequence similarity 111, member A |
| FMO4 | flavin containing monooxygenase 4 |
| FTH1P5 | ferritin, heavy polypeptide 1 pseudogene 5 |
| GAB2 | GRB2-associated binding protein 2 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GPALPP1 | GPALPP motifs containing 1 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HACD2 | 3-hydroxyacyl-CoA dehydratase 2 |
| INO80D | INO80 complex subunit D |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITPKC | inositol-trisphosphate 3-kinase C |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LOC642236 | FSHD region gene 1 pseudogene |
| LONRF3 | LON peptidase N-terminal domain and ring finger 3 |
| MAGT1 | magnesium transporter 1 |
| MRPL19 | mitochondrial ribosomal protein L19 |
| MT1HL1 | metallothionein 1H-like 1 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
| PABPC3 | poly(A) binding protein, cytoplasmic 3 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PJA1 | praja ring finger 1, E3 ubiquitin protein ligase |
| PKN1 | protein kinase N1 |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PTER | phosphotriesterase related |
| RBM4B | RNA binding motif protein 4B |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| RSF1 | remodeling and spacing factor 1 |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SH2B3 | SH2B adaptor protein 3 |
| SIRAL2 | SIR2 antiphage like 2 |
| SNHG3 | small nucleolar RNA host gene 3 |
| SPC25 | SPC25, NDC80 kinetochore complex component |
| SPON2 | spondin 2, extracellular matrix protein |
| SPR | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) |
| SPX | spexin hormone |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| TAC3 | tachykinin 3 |
| TBC1D31 | TBC1 domain family, member 31 |
| TCTN2 | tectonic family member 2 |
| TESK2 | testis-specific kinase 2 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) |
| TMEM115 | transmembrane protein 115 |
| TMEM14A | transmembrane protein 14A |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TOB1 | transducer of ERBB2, 1 |
| TTF2 | transcription termination factor, RNA polymerase II |
| TXNL4B | thioredoxin-like 4B |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| UBP1 | upstream binding protein 1 (LBP-1a) |
| UBQLN4 | ubiquilin 4 |
| UFM1 | ubiquitin-fold modifier 1 |
| USB1 | U6 snRNA biogenesis 1 |
| ZC3H12A | zinc finger CCCH-type containing 12A |
| ZCCHC8 | zinc finger, CCHC domain containing 8 |
| ZDHHC13 | zinc finger, DHHC-type containing 13 |
| ZNF268 | zinc finger protein 268 |
| ZNF33B | zinc finger protein 33B |
| ZNF432 | zinc finger protein 432 |
