famotidine-5011 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the famotidine-5011 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
ALOX12 arachidonate 12-lipoxygenase
ALOX5 arachidonate 5-lipoxygenase
ATN1 atrophin 1
BARX2 BARX homeobox 2
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BBS9 Bardet-Biedl syndrome 9
BHLHE40 basic helix-loop-helix family, member e40
BIN1 bridging integrator 1
C9ORF9 chromosome 9 open reading frame 9
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAPN9 calpain 9
CCDC134 coiled-coil domain containing 134
CD58 CD58 molecule
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CLCN7 chloride channel, voltage-sensitive 7
CLTC clathrin, heavy chain (Hc)
CTSE cathepsin E
DGCR2 DiGeorge syndrome critical region gene 2
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
DOK4 docking protein 4
DPF3 D4, zinc and double PHD fingers, family 3
DSC3 desmocollin 3
EFR3B EFR3 homolog B (S. cerevisiae)
EGFL7 EGF-like-domain, multiple 7
ERCC2 excision repair cross-complementation group 2
ETV5 ets variant 5
FGFR3 fibroblast growth factor receptor 3
FLJ42627 uncharacterized LOC645644
FSCN1 fascin actin-bundling protein 1
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GAST gastrin
GFI1 growth factor independent 1 transcription repressor
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GLP1R glucagon-like peptide 1 receptor
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GNRHR gonadotropin-releasing hormone receptor
GPM6A glycoprotein M6A
GRB10 growth factor receptor-bound protein 10
GRPR gastrin-releasing peptide receptor
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HFE hemochromatosis
HIST1H2BN histone cluster 1, H2bn
IL1RN interleukin 1 receptor antagonist
ING1 inhibitor of growth family, member 1
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCTD7 potassium channel tetramerization domain containing 7
KLHL29 kelch-like family member 29
KRT24 keratin 24, type I
LMX1B LIM homeobox transcription factor 1, beta
MBNL2 muscleblind-like splicing regulator 2
MKL1 megakaryoblastic leukemia (translocation) 1
MMP3 matrix metallopeptidase 3
MYOZ1 myozenin 1
NEURL1 neuralized E3 ubiquitin protein ligase 1
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PADI1 peptidyl arginine deiminase, type I
PARVA parvin, alpha
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PPARG peroxisome proliferator-activated receptor gamma
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PYHIN1 pyrin and HIN domain family, member 1
RAB40AL RAB40A, member RAS oncogene family-like
RAD23B RAD23 homolog B (S. cerevisiae)
RBMS2 RNA binding motif, single stranded interacting protein 2
RHBG Rh family, B glycoprotein (gene/pseudogene)
RHOBTB2 Rho-related BTB domain containing 2
RUNX1 runt-related transcription factor 1
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SETBP1 SET binding protein 1
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SMG7 SMG7 nonsense mediated mRNA decay factor
SMIM14 small integral membrane protein 14
SPARCL1 SPARC-like 1 (hevin)
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SSX3 synovial sarcoma, X breakpoint 3
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
STEAP4 STEAP family member 4
SYNDIG1 synapse differentiation inducing 1
TBXA2R thromboxane A2 receptor
TLDC1 TBC/LysM-associated domain containing 1
TTC9 tetratricopeptide repeat domain 9
TTLL3 tubulin tyrosine ligase-like family member 3
UNC93B1 unc-93 homolog B1 (C. elegans)
VIPR2 vasoactive intestinal peptide receptor 2
WIPI2 WD repeat domain, phosphoinositide interacting 2
XAF1 XIAP associated factor 1
ZBTB33 zinc finger and BTB domain containing 33
ZNF37BP zinc finger protein 37B, pseudogene

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ACSL4 acyl-CoA synthetase long-chain family member 4
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AXIN1 axin 1
BLNK B-cell linker
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
BTF3P11 basic transcription factor 3 pseudogene 11
CCDC132 coiled-coil domain containing 132
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CIC capicua transcriptional repressor
CISH cytokine inducible SH2-containing protein
CNGB3 cyclic nucleotide gated channel beta 3
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
DCAF13 DDB1 and CUL4 associated factor 13
DGKE diacylglycerol kinase, epsilon 64kDa
DOCK4 dedicator of cytokinesis 4
EFNA3 ephrin-A3
EN2 engrailed homeobox 2
ENO2 enolase 2 (gamma, neuronal)
ETAA1 Ewing tumor-associated antigen 1
FAM155A family with sequence similarity 155, member A
FAN1 FANCD2/FANCI-associated nuclease 1
FBXL2 F-box and leucine-rich repeat protein 2
FBXO22 F-box protein 22
FSTL3 follistatin-like 3 (secreted glycoprotein)
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GMEB1 glucocorticoid modulatory element binding protein 1
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
HYI hydroxypyruvate isomerase (putative)
IFI27 interferon, alpha-inducible protein 27
IFT54 intraflagellar transport 54
INO80D INO80 complex subunit D
ITPKB inositol-trisphosphate 3-kinase B
KIAA0355 KIAA0355
KIF13B kinesin family member 13B
LAMA3 laminin, alpha 3
LHX6 LIM homeobox 6
LRRC61 leucine rich repeat containing 61
MALL mal, T-cell differentiation protein-like
MAP3K6 mitogen-activated protein kinase kinase kinase 6
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTA2 metastasis associated 1 family, member 2
MYO9A myosin IXA
N4BP3 NEDD4 binding protein 3
NECAP2 NECAP endocytosis associated 2
NIPAL2 NIPA-like domain containing 2
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae)
NPIPB3 nuclear pore complex interacting protein family, member B3
OR12D2 olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
OVGP1 oviductal glycoprotein 1, 120kDa
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PAIP2B poly(A) binding protein interacting protein 2B
PCDHGB5 protocadherin gamma subfamily B, 5
PGBD5 piggyBac transposable element derived 5
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLA2G10 phospholipase A2, group X
PLAU plasminogen activator, urokinase
PLEKHO1 pleckstrin homology domain containing, family O member 1
PRKCE protein kinase C, epsilon
PRODH proline dehydrogenase (oxidase) 1
PTDSS2 phosphatidylserine synthase 2
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RGS17 regulator of G-protein signaling 17
RGS2 regulator of G-protein signaling 2
ROM1 retinal outer segment membrane protein 1
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
S100A9 S100 calcium binding protein A9
SCPEP1 serine carboxypeptidase 1
SCRN3 secernin 3
SIX1 SIX homeobox 1
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SLN sarcolipin
SPINK5 serine peptidase inhibitor, Kazal type 5
SYT17 synaptotagmin XVII
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TBC1D19 TBC1 domain family, member 19
TEX40 testis expressed 40
TMEM132A transmembrane protein 132A
TSGA10 testis specific, 10
TTC30A tetratricopeptide repeat domain 30A
TUBA4B tubulin, alpha 4b
UPK3B uroplakin 3B
USP20 ubiquitin specific peptidase 20
VAX2 ventral anterior homeobox 2
WBP2 WW domain binding protein 2
WDR3 WD repeat domain 3
WDR4 WD repeat domain 4
ZBTB25 zinc finger and BTB domain containing 25
ZBTB48 zinc finger and BTB domain containing 48
ZNF329 zinc finger protein 329
ZNF34 zinc finger protein 34
ZNF350 zinc finger protein 350
ZNF639 zinc finger protein 639