famotidine-6665 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the famotidine-6665 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM12 ADAM metallopeptidase domain 12
ANP32A-IT1 ANP32A intronic transcript 1
BAIAP3 BAI1-associated protein 3
BRSK2 BR serine/threonine kinase 2
BTNL8 butyrophilin-like 8
C11ORF16 chromosome 11 open reading frame 16
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CASR calcium-sensing receptor
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCR7 chemokine (C-C motif) receptor 7
CNPY4 canopy FGF signaling regulator 4
COL14A1 collagen, type XIV, alpha 1
CRHR2 corticotropin releasing hormone receptor 2
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DAPK2 death-associated protein kinase 2
DAPK3 death-associated protein kinase 3
DICER1 dicer 1, ribonuclease type III
DSC1 desmocollin 1
EFNB1 ephrin-B1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
F2RL2 coagulation factor II (thrombin) receptor-like 2
FAM149A family with sequence similarity 149, member A
FAM149B1 family with sequence similarity 149, member B1
FBXO40 F-box protein 40
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FGF22 fibroblast growth factor 22
FGF8 fibroblast growth factor 8 (androgen-induced)
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXO4 forkhead box O4
GCNT4 glucosaminyl (N-acetyl) transferase 4, core 2
GIF gastric intrinsic factor (vitamin B synthesis)
GRM1 glutamate receptor, metabotropic 1
GRM7 glutamate receptor, metabotropic 7
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HAP1 huntingtin-associated protein 1
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IGFBP7 insulin-like growth factor binding protein 7
IKZF1 IKAROS family zinc finger 1 (Ikaros)
INPP5J inositol polyphosphate-5-phosphatase J
KCNJ13 potassium channel, inwardly rectifying subfamily J, member 13
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KLF9 Kruppel-like factor 9
KLK13 kallikrein-related peptidase 13
KLRF1 killer cell lectin-like receptor subfamily F, member 1
KMT2A lysine (K)-specific methyltransferase 2A
LBX1 ladybird homeobox 1
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LMOD1 leiomodin 1 (smooth muscle)
LOC100131532 uncharacterized LOC100131532
LRRN3 leucine rich repeat neuronal 3
MAPK8 mitogen-activated protein kinase 8
MCFD2 multiple coagulation factor deficiency 2
MOGAT2 monoacylglycerol O-acyltransferase 2
MPZ myelin protein zero
MRPL20 mitochondrial ribosomal protein L20
MTSS1L metastasis suppressor 1-like
MYO7B myosin VIIB
NCAM1 neural cell adhesion molecule 1
NIPAL2 NIPA-like domain containing 2
NOX1 NADPH oxidase 1
NR1H4 nuclear receptor subfamily 1, group H, member 4
PENK proenkephalin
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PIGO phosphatidylinositol glycan anchor biosynthesis, class O
PMP2 peripheral myelin protein 2
POU6F1 POU class 6 homeobox 1
PPP2R5A protein phosphatase 2, regulatory subunit B', alpha
PRIM2 primase, DNA, polypeptide 2 (58kDa)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
QPCT glutaminyl-peptide cyclotransferase
RPL10L ribosomal protein L10-like
S100A11 S100 calcium binding protein A11
SAA3P serum amyloid A3 pseudogene
SCAND2P SCAN domain containing 2 pseudogene
SCGB1D2 secretoglobin, family 1D, member 2
SIGLEC8 sialic acid binding Ig-like lectin 8
SLAMF8 SLAM family member 8
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
SPARCL1 SPARC-like 1 (hevin)
SSX1 synovial sarcoma, X breakpoint 1
SSX3 synovial sarcoma, X breakpoint 3
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TG thyroglobulin
TIMP4 TIMP metallopeptidase inhibitor 4
TNNT3 troponin T type 3 (skeletal, fast)
TNPO2 transportin 2
TPM2 tropomyosin 2 (beta)
TRAF3IP3 TRAF3 interacting protein 3
TRIM49 tripartite motif containing 49
TTLL4 tubulin tyrosine ligase-like family member 4
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)

decreased expression

Symbol Name
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACADSB acyl-CoA dehydrogenase, short/branched chain
ADGRG2 adhesion G protein-coupled receptor G2
ANXA2P1 annexin A2 pseudogene 1
APOL6 apolipoprotein L, 6
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ATAD5 ATPase family, AAA domain containing 5
ATF7IP2 activating transcription factor 7 interacting protein 2
AXIN1 axin 1
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
C14ORF93 chromosome 14 open reading frame 93
C1S complement component 1, s subcomponent
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CHMP1A charged multivesicular body protein 1A
CNN2 calponin 2
CNTNAP1 contactin associated protein 1
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DLL3 delta-like 3 (Drosophila)
EPPK1 epiplakin 1
ERF Ets2 repressor factor
ETNK2 ethanolamine kinase 2
FBXL7 F-box and leucine-rich repeat protein 7
FMO4 flavin containing monooxygenase 4
FZD3 frizzled class receptor 3
GDAP1 ganglioside induced differentiation associated protein 1
GLS2 glutaminase 2 (liver, mitochondrial)
GLT8D2 glycosyltransferase 8 domain containing 2
GMPR guanosine monophosphate reductase
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPC3 glypican 3
GRAMD1C GRAM domain containing 1C
GSTCD glutathione S-transferase, C-terminal domain containing
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
HDAC7 histone deacetylase 7
HLX H2.0-like homeobox
HOMER2 homer scaffolding protein 2
HOXA2 homeobox A2
HOXA4 homeobox A4
HOXC8 homeobox C8
IQSEC2 IQ motif and Sec7 domain 2
KIAA0319L KIAA0319-like
KIAA0513 KIAA0513
KIAA0753 KIAA0753
KIAA0922 KIAA0922
KIAA1107 KIAA1107
KIAA1456 KIAA1456
LIG4 ligase IV, DNA, ATP-dependent
LIPG lipase, endothelial
LMNB1 lamin B1
LMO7 LIM domain 7
LNPEP leucyl/cystinyl aminopeptidase
LOC730101 uncharacterized LOC730101
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
NR3C2 nuclear receptor subfamily 3, group C, member 2
NSD1 nuclear receptor binding SET domain protein 1
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
POLM polymerase (DNA directed), mu
POMT2 protein-O-mannosyltransferase 2
PRB3 proline-rich protein BstNI subfamily 3
PRKX protein kinase, X-linked
PTK6 protein tyrosine kinase 6
PTPRE protein tyrosine phosphatase, receptor type, E
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RHOBTB2 Rho-related BTB domain containing 2
RPH3AL rabphilin 3A-like (without C2 domains)
SCEL sciellin
SERINC5 serine incorporator 5
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SETD8 SET domain containing (lysine methyltransferase) 8
SHROOM2 shroom family member 2
SLC12A9 solute carrier family 12, member 9
SLC25A40 solute carrier family 25, member 40
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
ST5 suppression of tumorigenicity 5
SYNGR3 synaptogyrin 3
THBS3 thrombospondin 3
TMC7 transmembrane channel-like 7
TMSB15A thymosin beta 15a
TOM1 target of myb1 (chicken)
TPST2 tyrosylprotein sulfotransferase 2
TRDMT1 tRNA aspartic acid methyltransferase 1
TUBA4B tubulin, alpha 4b
USP18 ubiquitin specific peptidase 18
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
VWA1 von Willebrand factor A domain containing 1
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZBTB44 zinc finger and BTB domain containing 44
ZMYM3 zinc finger, MYM-type 3
ZNF215 zinc finger protein 215
ZNF510 zinc finger protein 510
ZNF528 zinc finger protein 528
ZNF76 zinc finger protein 76
ZNRD1-AS1 ZNRD1 antisense RNA 1
ZW10 zw10 kinetochore protein