famprofazone-2174 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the famprofazone-2174 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AKAP8L A kinase (PRKA) anchor protein 8-like
ALDOB aldolase B, fructose-bisphosphate
AP4S1 adaptor-related protein complex 4, sigma 1 subunit
APOE apolipoprotein E
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
ASB4 ankyrin repeat and SOCS box containing 4
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BAIAP2 BAI1-associated protein 2
BTN3A1 butyrophilin, subfamily 3, member A1
C20ORF27 chromosome 20 open reading frame 27
CCDC92 coiled-coil domain containing 92
CCKAR cholecystokinin A receptor
CCL22 chemokine (C-C motif) ligand 22
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CFHR4 complement factor H-related 4
DCSTAMP dendrocyte expressed seven transmembrane protein
DDAH2 dimethylarginine dimethylaminohydrolase 2
DEFA4 defensin, alpha 4, corticostatin
DNAH17 dynein, axonemal, heavy chain 17
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DPF1 D4, zinc and double PHD fingers family 1
DSPP dentin sialophosphoprotein
DTNB dystrobrevin, beta
EGR3 early growth response 3
EML3 echinoderm microtubule associated protein like 3
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FAM120C family with sequence similarity 120C
FAM49B family with sequence similarity 49, member B
FAM86C1 family with sequence similarity 86, member C1
FKBP8 FK506 binding protein 8, 38kDa
FZD1 frizzled class receptor 1
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GPR153 G protein-coupled receptor 153
GRM1 glutamate receptor, metabotropic 1
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HBB hemoglobin, beta
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HOXA10 homeobox A10
HOXB6 homeobox B6
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
HYAL3 hyaluronoglucosaminidase 3
ICOSLG inducible T-cell co-stimulator ligand
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IGFBP4 insulin-like growth factor binding protein 4
IHH indian hedgehog
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KXD1 KxDL motif containing 1
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LMF1 lipase maturation factor 1
MAP4 microtubule-associated protein 4
MAPK7 mitogen-activated protein kinase 7
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MBP myelin basic protein
MIA2 melanoma inhibitory activity 2
MOB3B MOB kinase activator 3B
MPDZ multiple PDZ domain protein
MT1G metallothionein 1G
MYCT1 myc target 1
NPEPL1 aminopeptidase-like 1
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
NUP214 nucleoporin 214kDa
PKNOX1 PBX/knotted 1 homeobox 1
PPP1R14D protein phosphatase 1, regulatory (inhibitor) subunit 14D
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RNF39 ring finger protein 39
RPL10 ribosomal protein L10
RPL7 ribosomal protein L7
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
SCN11A sodium channel, voltage gated, type XI alpha subunit
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
STARD13 StAR-related lipid transfer (START) domain containing 13
STON1 stonin 1
SYNGR3 synaptogyrin 3
T T, brachyury homolog (mouse)
TACC2 transforming, acidic coiled-coil containing protein 2
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
THBS1 thrombospondin 1
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
VIPR2 vasoactive intestinal peptide receptor 2
ZC3H7B zinc finger CCCH-type containing 7B
ZMAT4 zinc finger, matrin-type 4
ZNF137P zinc finger protein 137, pseudogene
ZNF407 zinc finger protein 407
ZXDB zinc finger, X-linked, duplicated B

decreased expression

Symbol Name
ABCA11P ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene
ABHD17B abhydrolase domain containing 17B
ACP6 acid phosphatase 6, lysophosphatidic
ADORA3 adenosine A3 receptor
AMT aminomethyltransferase
AP5S1 adaptor-related protein complex 5, sigma 1 subunit
ARHGAP11A Rho GTPase activating protein 11A
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3
ASGR2 asialoglycoprotein receptor 2
ASPN asporin
BATF basic leucine zipper transcription factor, ATF-like
BSPRY B-box and SPRY domain containing
BZRAP1 benzodiazepine receptor (peripheral) associated protein 1
C1RL complement component 1, r subcomponent-like
CD151 CD151 molecule (Raph blood group)
CD1D CD1d molecule
CD320 CD320 molecule
CDA cytidine deaminase
CDK3 cyclin-dependent kinase 3
CEP72 centrosomal protein 72kDa
CHML choroideremia-like (Rab escort protein 2)
CLCF1 cardiotrophin-like cytokine factor 1
CLGN calmegin
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CNR2 cannabinoid receptor 2 (macrophage)
COG4 component of oligomeric golgi complex 4
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CST3 cystatin C
CTNNBIP1 catenin, beta interacting protein 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DCAF13 DDB1 and CUL4 associated factor 13
DEAF1 DEAF1 transcription factor
ERAP2 endoplasmic reticulum aminopeptidase 2
ERN2 endoplasmic reticulum to nucleus signaling 2
ERO1LB ERO1-like beta (S. cerevisiae)
FAM204A family with sequence similarity 204, member A
FAM63A family with sequence similarity 63, member A
FMOD fibromodulin
FNBP1L formin binding protein 1-like
FOXN2 forkhead box N2
FSTL3 follistatin-like 3 (secreted glycoprotein)
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GFI1 growth factor independent 1 transcription repressor
GIMAP6 GTPase, IMAP family member 6
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GJA1 gap junction protein, alpha 1, 43kDa
GPR27 G protein-coupled receptor 27
GPR65 G protein-coupled receptor 65
GRAMD1B GRAM domain containing 1B
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
LNPEP leucyl/cystinyl aminopeptidase
LPAR6 lysophosphatidic acid receptor 6
MAGEB2 melanoma antigen family B2
MED9 mediator complex subunit 9
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MXD3 MAX dimerization protein 3
NARFL nuclear prelamin A recognition factor-like
NDE1 nudE neurodevelopment protein 1
NFE2L3 nuclear factor, erythroid 2-like 3
NINJ2 ninjurin 2
NPM3 nucleophosmin/nucleoplasmin 3
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PDLIM2 PDZ and LIM domain 2 (mystique)
PECR peroxisomal trans-2-enoyl-CoA reductase
PHACTR1 phosphatase and actin regulator 1
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAB13 RAB13, member RAS oncogene family
RAB23 RAB23, member RAS oncogene family
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RFXAP regulatory factor X-associated protein
RHBDF1 rhomboid 5 homolog 1 (Drosophila)
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
SERGEF secretion regulating guanine nucleotide exchange factor
SIRT6 sirtuin 6
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLITRK5 SLIT and NTRK-like family, member 5
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SNHG20 small nucleolar RNA host gene 20
SNRPN small nuclear ribonucleoprotein polypeptide N
SOX12 SRY (sex determining region Y)-box 12
STARD3 StAR-related lipid transfer (START) domain containing 3
THBS3 thrombospondin 3
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast)
TLR4 toll-like receptor 4
TMEM242 transmembrane protein 242
TMEM62 transmembrane protein 62
TRIM25 tripartite motif containing 25
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
USB1 U6 snRNA biogenesis 1
WASF3 WAS protein family, member 3
ZFAND3 zinc finger, AN1-type domain 3
ZNF250 zinc finger protein 250
ZNF574 zinc finger protein 574
ZNF747 zinc finger protein 747
ZW10 zw10 kinetochore protein