famprofazone-3834 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the famprofazone-3834 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A2M alpha-2-macroglobulin
ACVR1B activin A receptor, type IB
ADORA1 adenosine A1 receptor
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AGFG2 ArfGAP with FG repeats 2
ATN1 atrophin 1
BDNF brain-derived neurotrophic factor
BMP15 bone morphogenetic protein 15
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CASP1 caspase 1, apoptosis-related cysteine peptidase
CDO1 cysteine dioxygenase type 1
CHI3L2 chitinase 3-like 2
CHODL chondrolectin
COL13A1 collagen, type XIII, alpha 1
COL1A1 collagen, type I, alpha 1
CPA4 carboxypeptidase A4
CTIF CBP80/20-dependent translation initiation factor
CTSZ cathepsin Z
CXCL6 chemokine (C-X-C motif) ligand 6
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DFNB31 deafness, autosomal recessive 31
FADS2 fatty acid desaturase 2
FAM120C family with sequence similarity 120C
FAXDC2 fatty acid hydroxylase domain containing 2
FEZ1 fasciculation and elongation protein zeta 1 (zygin I)
FOXG1 forkhead box G1
FRMD1 FERM domain containing 1
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GAST gastrin
GFI1 growth factor independent 1 transcription repressor
GPER1 G protein-coupled estrogen receptor 1
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HCRTR2 hypocretin (orexin) receptor 2
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
ICAM1 intercellular adhesion molecule 1
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFITM1 interferon induced transmembrane protein 1
IL1B interleukin 1, beta
ING4 inhibitor of growth family, member 4
INHBE inhibin, beta E
IRF9 interferon regulatory factor 9
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KIAA0754 KIAA0754
KLHL25 kelch-like family member 25
KLRAP1 killer cell lectin-like receptor subfamily A pseudogene 1
KRT19P2 keratin 19 pseudogene 2
LAMP1 lysosomal-associated membrane protein 1
MAOB monoamine oxidase B
MEGF8 multiple EGF-like-domains 8
MGAM maltase-glucoamylase
MGC2889 uncharacterized protein MGC2889
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NOVA2 neuro-oncological ventral antigen 2
NR6A1 nuclear receptor subfamily 6, group A, member 1
NRXN3 neurexin 3
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
PCDHA5 protocadherin alpha 5
PDIA2 protein disulfide isomerase family A, member 2
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLAC4 placenta-specific 4
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
POPDC3 popeye domain containing 3
PRDX2 peroxiredoxin 2
PSCA prostate stem cell antigen
RFPL1 ret finger protein-like 1
RHOH ras homolog family member H
RNASE4 ribonuclease, RNase A family, 4
RPL35A ribosomal protein L35a
RSG1 REM2 and RAB-like small GTPase 1
RUNX1 runt-related transcription factor 1
S100A12 S100 calcium binding protein A12
SCUBE3 signal peptide, CUB domain, EGF-like 3
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SLCO4C1 solute carrier organic anion transporter family, member 4C1
SLURP1 secreted LY6/PLAUR domain containing 1
SWAP70 SWAP switching B-cell complex 70kDa subunit
SYCE1L synaptonemal complex central element protein 1-like
TBC1D8 TBC1 domain family, member 8 (with GRAM domain)
TBX3 T-box 3
TCF25 transcription factor 25 (basic helix-loop-helix)
TDRD12 tudor domain containing 12
THRB thyroid hormone receptor, beta
TMOD2 tropomodulin 2 (neuronal)
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRIM2 tripartite motif containing 2
TTC38 tetratricopeptide repeat domain 38
TTLL1 tubulin tyrosine ligase-like family member 1
WNT10B wingless-type MMTV integration site family, member 10B
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase

decreased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
AHNAK2 AHNAK nucleoprotein 2
ALOX15 arachidonate 15-lipoxygenase
AMPD1 adenosine monophosphate deaminase 1
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ASAP1-IT1 ASAP1 intronic transcript 1
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BHLHE41 basic helix-loop-helix family, member e41
C10ORF95 chromosome 10 open reading frame 95
C22ORF46 chromosome 22 open reading frame 46
C8ORF44 chromosome 8 open reading frame 44
CALML5 calmodulin-like 5
CCDC71 coiled-coil domain containing 71
CD80 CD80 molecule
CDKL3 cyclin-dependent kinase-like 3
CENPO centromere protein O
CGREF1 cell growth regulator with EF-hand domain 1
CNGB3 cyclic nucleotide gated channel beta 3
CRYBB2P1 crystallin, beta B2 pseudogene 1
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DNM1 dynamin 1
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DYSF dysferlin
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EFNA3 ephrin-A3
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EPHB6 EPH receptor B6
F3 coagulation factor III (thromboplastin, tissue factor)
FGF4 fibroblast growth factor 4
FKBP5 FK506 binding protein 5
FLT4 fms-related tyrosine kinase 4
FMOD fibromodulin
FRS2 fibroblast growth factor receptor substrate 2
FUZ fuzzy planar cell polarity protein
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNL1 guanine nucleotide binding protein-like 1
GPATCH2L G patch domain containing 2-like
GPR21 G protein-coupled receptor 21
HIST1H4D histone cluster 1, H4d
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IDI2-AS1 IDI2 antisense RNA 1
IFNA14 interferon, alpha 14
IFT54 intraflagellar transport 54
IL12RB1 interleukin 12 receptor, beta 1
IPO8 importin 8
ITPKB inositol-trisphosphate 3-kinase B
JMJD4 jumonji domain containing 4
KIAA1107 KIAA1107
KIFC1 kinesin family member C1
KRI1 KRI1 homolog (S. cerevisiae)
KRT16 keratin 16, type I
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MBTPS2 membrane-bound transcription factor peptidase, site 2
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCOLN1 mucolipin 1
MEFV Mediterranean fever
MTERF4 mitochondrial transcription termination factor 4
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NPM3 nucleophosmin/nucleoplasmin 3
OLFML2A olfactomedin-like 2A
OVOL1 ovo-like zinc finger 1
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PLA2G3 phospholipase A2, group III
PLCD1 phospholipase C, delta 1
PMEL premelanosome protein
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RNF25 ring finger protein 25
S100A9 S100 calcium binding protein A9
SCYL2 SCY1-like 2 (S. cerevisiae)
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SLC39A1 solute carrier family 39 (zinc transporter), member 1
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
STARD8 StAR-related lipid transfer (START) domain containing 8
STON1 stonin 1
TCP10 t-complex 10
TONSL tonsoku-like, DNA repair protein
TRAF4 TNF receptor-associated factor 4
TRIM25 tripartite motif containing 25
TUBA3C tubulin, alpha 3c
TUBA4B tubulin, alpha 4b
UPK2 uroplakin 2
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
WDR33 WD repeat domain 33
ZBTB33 zinc finger and BTB domain containing 33
ZMAT4 zinc finger, matrin-type 4
ZNF358 zinc finger protein 358
ZNF428 zinc finger protein 428
ZNF446 zinc finger protein 446
ZNF484 zinc finger protein 484
ZNF639 zinc finger protein 639
ZNF862 zinc finger protein 862