famprofazone-4309 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the famprofazone-4309 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ADGRG1 adhesion G protein-coupled receptor G1
ADGRL2 adhesion G protein-coupled receptor L2
ADRA2B adrenoceptor alpha 2B
AHSP alpha hemoglobin stabilizing protein
ALK anaplastic lymphoma receptor tyrosine kinase
AMHR2 anti-Mullerian hormone receptor, type II
ANGPTL2 angiopoietin-like 2
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
BCL3 B-cell CLL/lymphoma 3
C17ORF59 chromosome 17 open reading frame 59
C4BPA complement component 4 binding protein, alpha
CA12 carbonic anhydrase XII
CBS cystathionine-beta-synthase
CCL27 chemokine (C-C motif) ligand 27
CD4 CD4 molecule
CDK10 cyclin-dependent kinase 10
CDX1 caudal type homeobox 1
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
COL1A2 collagen, type I, alpha 2
COL6A1 collagen, type VI, alpha 1
CSHL1 chorionic somatomammotropin hormone-like 1
CSNK1E casein kinase 1, epsilon
CTSZ cathepsin Z
DKFZP434C153 DKFZP434C153 protein
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DRD5 dopamine receptor D5
DSCAM Down syndrome cell adhesion molecule
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FEZ2 fasciculation and elongation protein zeta 2 (zygin II)
FGF1 fibroblast growth factor 1 (acidic)
GABARAPL3 GABA(A) receptors associated protein like 3, pseudogene
GPR157 G protein-coupled receptor 157
GSTTP1 glutathione S-transferase theta pseudogene 1
HIP1 huntingtin interacting protein 1
HMGA1 high mobility group AT-hook 1
HSF1 heat shock transcription factor 1
HSPG2 heparan sulfate proteoglycan 2
IL32 interleukin 32
IL9R interleukin 9 receptor
IQSEC2 IQ motif and Sec7 domain 2
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KLF12 Kruppel-like factor 12
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAP2K7 mitogen-activated protein kinase kinase 7
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAPK7 mitogen-activated protein kinase 7
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MED25 mediator complex subunit 25
MGC2889 uncharacterized protein MGC2889
MT4 metallothionein 4
MUC3B mucin 3B, cell surface associated
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYO9B myosin IXB
NEUROD4 neuronal differentiation 4
NGF nerve growth factor (beta polypeptide)
OSBPL7 oxysterol binding protein-like 7
OXCT2 3-oxoacid CoA transferase 2
PAPPA2 pappalysin 2
PDE4A phosphodiesterase 4A, cAMP-specific
PDPN podoplanin
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLK3 polo-like kinase 3
POFUT2 protein O-fucosyltransferase 2
PTGIS prostaglandin I2 (prostacyclin) synthase
PXN paxillin
RAB11B RAB11B, member RAS oncogene family
RAP1GAP RAP1 GTPase activating protein
RIC3 RIC3 acetylcholine receptor chaperone
RNF122 ring finger protein 122
RUNX1 runt-related transcription factor 1
SAPCD1 suppressor APC domain containing 1
SH3BP2 SH3-domain binding protein 2
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
SNX29 sorting nexin 29
SP140 SP140 nuclear body protein
SPPL2B signal peptide peptidase like 2B
SPRR1B small proline-rich protein 1B
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
SULF1 sulfatase 1
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae)
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TNPO2 transportin 2
TRAPPC9 trafficking protein particle complex 9
TRIM3 tripartite motif containing 3
TUBA3C tubulin, alpha 3c
ULBP1 UL16 binding protein 1
XYLB xylulokinase homolog (H. influenzae)
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
ZNF710 zinc finger protein 710

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ADGRB2 adhesion G protein-coupled receptor B2
ANKRD36 ankyrin repeat domain 36
ANXA10 annexin A10
ATAD5 ATPase family, AAA domain containing 5
AZI2 5-azacytidine induced 2
BEND5 BEN domain containing 5
C17ORF75 chromosome 17 open reading frame 75
C1R complement component 1, r subcomponent
C7ORF43 chromosome 7 open reading frame 43
CCNO cyclin O
CEMIP cell migration inducing protein, hyaluronan binding
CENPJ centromere protein J
CENPO centromere protein O
CORT cortistatin
CREB5 cAMP responsive element binding protein 5
CTSF cathepsin F
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DUSP8 dual specificity phosphatase 8
EHF ets homologous factor
EPN3 epsin 3
FBXW12 F-box and WD repeat domain containing 12
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GK3P glycerol kinase 3 pseudogene
GMEB1 glucocorticoid modulatory element binding protein 1
GSTCD glutathione S-transferase, C-terminal domain containing
GUSBP3 glucuronidase, beta pseudogene 3
HAUS6 HAUS augmin-like complex, subunit 6
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HIST1H2AM histone cluster 1, H2am
HIST1H4C histone cluster 1, H4c
IFI6 interferon, alpha-inducible protein 6
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IKZF5 IKAROS family zinc finger 5 (Pegasus)
INTS6 integrator complex subunit 6
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KIAA1107 KIAA1107
KIRREL kin of IRRE like (Drosophila)
LRRC37A4P leucine rich repeat containing 37, member A4, pseudogene
MANSC1 MANSC domain containing 1
MATN3 matrilin 3
MIS18BP1 MIS18 binding protein 1
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
NAP1L3 nucleosome assembly protein 1-like 3
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NKX3-2 NK3 homeobox 2
NOL10 nucleolar protein 10
NR1H3 nuclear receptor subfamily 1, group H, member 3
NRTN neurturin
NT5C 5', 3'-nucleotidase, cytosolic
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
NUP62CL nucleoporin 62kDa C-terminal like
NUTF2 nuclear transport factor 2
PADI1 peptidyl arginine deiminase, type I
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PER3 period circadian clock 3
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PMCH pro-melanin-concentrating hormone
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PTPRE protein tyrosine phosphatase, receptor type, E
PTTG3P pituitary tumor-transforming 3, pseudogene
RAB33B RAB33B, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAD51AP1 RAD51 associated protein 1
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RPS14P3 ribosomal protein S14 pseudogene 3
RSF1 remodeling and spacing factor 1
SETD1B SET domain containing 1B
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC35F6 solute carrier family 35, member F6
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SMAD5 SMAD family member 5
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SRD5A3 steroid 5 alpha-reductase 3
STAG3L4 stromal antigen 3-like 4 (pseudogene)
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TESK1 testis-specific kinase 1
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM19 transmembrane protein 19
TMEM53 transmembrane protein 53
TUBA4B tubulin, alpha 4b
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
WDR41 WD repeat domain 41
ZFP30 ZFP30 zinc finger protein
ZNF141 zinc finger protein 141
ZNF215 zinc finger protein 215
ZNF480 zinc finger protein 480
ZNF669 zinc finger protein 669
ZNF76 zinc finger protein 76
ZNF862 zinc finger protein 862