fasting hyperinsulinemia Gene Set

Dataset GWASdb SNP-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description An increased concentration of insulin in the blood in the fasting state, i.e., not as the response to food intake. (Human Phenotype Ontology, HP_0008283)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/HP:0008283
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Genes

27 genes associated with the fasting hyperinsulinemia phenotype in GWAS datasets from the GWASdb SNP-Phenotype Associations dataset.

Symbol Name Standardized Value
G6PC2 glucose-6-phosphatase, catalytic, 2 3.4216
MTNR1B melatonin receptor 1B 3.27214
GCKR glucokinase (hexokinase 4) regulator 2.3565
ADCY5 adenylate cyclase 5 2.03563
COBLL1 cordon-bleu WH2 repeat protein-like 1 1.95098
MADD MAP-kinase activating death domain 1.88591
FADS1 fatty acid desaturase 1 1.74205
CRY2 cryptochrome circadian clock 2 1.68604
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 1.57026
GLIS3 GLIS family zinc finger 3 1.5645
SLC30A8 solute carrier family 30 (zinc transporter), member 8 1.47083
IGF1 insulin-like growth factor 1 (somatomedin C) 1.32793
PDGFC platelet derived growth factor C 1.28282
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 1.24751
PEPD peptidase D 1.15743
PPARG peroxisome proliferator-activated receptor gamma 1.12851
SYN2 synapsin II 1.12851
AKAP6 A kinase (PRKA) anchor protein 6 1.08774
SPAG16 sperm associated antigen 16 1.07729
SULF1 sulfatase 1 1.0674
CLSTN2 calsyntenin 2 0.969142
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 0.942765
PTCHD3 patched domain containing 3 0.919744
SNX29 sorting nexin 29 0.873412
TMEM135 transmembrane protein 135 0.694714
CCDC109B coiled-coil domain containing 109B 0.522421
ALK anaplastic lymphoma receptor tyrosine kinase 0.504316