| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the fasudil-343 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 |
| ANKRD40 | ankyrin repeat domain 40 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| BAIAP2 | BAI1-associated protein 2 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BCLAF1 | BCL2-associated transcription factor 1 |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| C16ORF58 | chromosome 16 open reading frame 58 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CCDC7 | coiled-coil domain containing 7 |
| CD5 | CD5 molecule |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CHRM4 | cholinergic receptor, muscarinic 4 |
| CIDEB | cell death-inducing DFFA-like effector b |
| CLDN15 | claudin 15 |
| CNP | 2',3'-cyclic nucleotide 3' phosphodiesterase |
| CORO2A | coronin, actin binding protein, 2A |
| CPNE7 | copine VII |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 |
| CSTF1 | cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa |
| CUL4B | cullin 4B |
| DBR1 | debranching RNA lariats 1 |
| ELAVL4 | ELAV like neuron-specific RNA binding protein 4 |
| ELMO2 | engulfment and cell motility 2 |
| ERCC4 | excision repair cross-complementation group 4 |
| FAM153A | family with sequence similarity 153, member A |
| FAM175B | family with sequence similarity 175, member B |
| FGFR1 | fibroblast growth factor receptor 1 |
| FUT2 | fucosyltransferase 2 (secretor status included) |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GAS7 | growth arrest-specific 7 |
| GLMN | glomulin, FKBP associated protein |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GRPR | gastrin-releasing peptide receptor |
| GUF1 | GUF1 GTPase homolog (S. cerevisiae) |
| HEG1 | heart development protein with EGF-like domains 1 |
| HEXA | hexosaminidase A (alpha polypeptide) |
| HINFP | histone H4 transcription factor |
| HTR1B | 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled |
| HUS1 | HUS1 checkpoint homolog (S. pombe) |
| IL15RA | interleukin 15 receptor, alpha |
| IL1B | interleukin 1, beta |
| IL6ST | interleukin 6 signal transducer |
| JADE3 | jade family PHD finger 3 |
| JOSD1 | Josephin domain containing 1 |
| KBTBD4 | kelch repeat and BTB (POZ) domain containing 4 |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| LINC00216 | long intergenic non-protein coding RNA 216 |
| LUZP4 | leucine zipper protein 4 |
| MAGEA5 | melanoma antigen family A5 |
| MEFV | Mediterranean fever |
| MTCP1 | mature T-cell proliferation 1 |
| MTRR | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase |
| MYL10 | myosin, light chain 10, regulatory |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NACA | nascent polypeptide-associated complex alpha subunit |
| NAP1L1 | nucleosome assembly protein 1-like 1 |
| NOVA1 | neuro-oncological ventral antigen 1 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NUP188 | nucleoporin 188kDa |
| OR10H3 | olfactory receptor, family 10, subfamily H, member 3 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 |
| PDHA2 | pyruvate dehydrogenase (lipoamide) alpha 2 |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PEX11A | peroxisomal biogenesis factor 11 alpha |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 |
| QSER1 | glutamine and serine rich 1 |
| RHOBTB3 | Rho-related BTB domain containing 3 |
| RPS2 | ribosomal protein S2 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| S100A3 | S100 calcium binding protein A3 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SEC23B | Sec23 homolog B (S. cerevisiae) |
| SEC63 | SEC63 homolog (S. cerevisiae) |
| SERPINI2 | serpin peptidase inhibitor, clade I (pancpin), member 2 |
| SETD4 | SET domain containing 4 |
| SH3BP2 | SH3-domain binding protein 2 |
| SNRPN | small nuclear ribonucleoprotein polypeptide N |
| SOD2 | superoxide dismutase 2, mitochondrial |
| SON | SON DNA binding protein |
| SPEG | SPEG complex locus |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TOB2 | transducer of ERBB2, 2 |
| TOLLIP | toll interacting protein |
| TRAFD1 | TRAF-type zinc finger domain containing 1 |
| TRBC1 | T cell receptor beta constant 1 |
| TRIM2 | tripartite motif containing 2 |
| TRIP11 | thyroid hormone receptor interactor 11 |
| TYR | tyrosinase |
| UBE4B | ubiquitination factor E4B |
| WDR18 | WD repeat domain 18 |
| WWTR1 | WW domain containing transcription regulator 1 |
| ZNF154 | zinc finger protein 154 |
| Symbol | Name |
|---|---|
| ADAM30 | ADAM metallopeptidase domain 30 |
| ADGRE1 | adhesion G protein-coupled receptor E1 |
| AXIN1 | axin 1 |
| BTBD2 | BTB (POZ) domain containing 2 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C2CD2 | C2 calcium-dependent domain containing 2 |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CBX7 | chromobox homolog 7 |
| CBX8 | chromobox homolog 8 |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CD2 | CD2 molecule |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CLEC4E | C-type lectin domain family 4, member E |
| CNTD2 | cyclin N-terminal domain containing 2 |
| CNTN1 | contactin 1 |
| CRYGB | crystallin, gamma B |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DYSF | dysferlin |
| ECM1 | extracellular matrix protein 1 |
| EGFL7 | EGF-like-domain, multiple 7 |
| EN2 | engrailed homeobox 2 |
| ERO1L | ERO1-like (S. cerevisiae) |
| EVPL | envoplakin |
| F2 | coagulation factor II (thrombin) |
| FAM171A1 | family with sequence similarity 171, member A1 |
| FOXC1 | forkhead box C1 |
| GAB2 | GRB2-associated binding protein 2 |
| GMIP | GEM interacting protein |
| HSD17B3 | hydroxysteroid (17-beta) dehydrogenase 3 |
| IFNA4 | interferon, alpha 4 |
| KIR2DS1 | killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1 |
| KLF11 | Kruppel-like factor 11 |
| KLF15 | Kruppel-like factor 15 |
| KLHL26 | kelch-like family member 26 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| LMTK1 | lemur tail kinase 1 |
| LRRC49 | leucine rich repeat containing 49 |
| LRRC61 | leucine rich repeat containing 61 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) |
| MECR | mitochondrial trans-2-enoyl-CoA reductase |
| MEPE | matrix extracellular phosphoglycoprotein |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MIP | major intrinsic protein of lens fiber |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
| MYOC | myocilin, trabecular meshwork inducible glucocorticoid response |
| NDRG4 | NDRG family member 4 |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 |
| NEUROD6 | neuronal differentiation 6 |
| NOX5 | NADPH oxidase, EF-hand calcium binding domain 5 |
| NR0B2 | nuclear receptor subfamily 0, group B, member 2 |
| NRSN2 | neurensin 2 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| PCDHB6 | protocadherin beta 6 |
| PFKFB1 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
| PLCD1 | phospholipase C, delta 1 |
| PQLC3 | PQ loop repeat containing 3 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) |
| PRY | PTPN13-like, Y-linked |
| RASL12 | RAS-like, family 12 |
| RBPJL | recombination signal binding protein for immunoglobulin kappa J region-like |
| RNF186 | ring finger protein 186 |
| S100A9 | S100 calcium binding protein A9 |
| SCN5A | sodium channel, voltage gated, type V alpha subunit |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLC13A4 | solute carrier family 13 (sodium/sulfate symporter), member 4 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SMA4 | glucuronidase, beta pseudogene |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SNTA1 | syntrophin, alpha 1 |
| STAC | SH3 and cysteine rich domain |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| SURF2 | surfeit 2 |
| T | T, brachyury homolog (mouse) |
| TCEA2 | transcription elongation factor A (SII), 2 |
| TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 |
| TCTN1 | tectonic family member 1 |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TMEM176A | transmembrane protein 176A |
| TMEM53 | transmembrane protein 53 |
| TMEM57 | transmembrane protein 57 |
| TNF | tumor necrosis factor |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TTR | transthyretin |
| VEGFB | vascular endothelial growth factor B |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| WDR13 | WD repeat domain 13 |
| WNT3 | wingless-type MMTV integration site family, member 3 |
| XYLT2 | xylosyltransferase II |
| ZCCHC6 | zinc finger, CCHC domain containing 6 |
| ZFP36 | ZFP36 ring finger protein |
| ZIC1 | Zic family member 1 |
| ZNF701 | zinc finger protein 701 |