felbinac-3398 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the felbinac-3398 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRL1 adhesion G protein-coupled receptor L1
ANO2 anoctamin 2, calcium activated chloride channel
ARTN artemin
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ATG10 autophagy related 10
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
C10ORF95 chromosome 10 open reading frame 95
C9ORF16 chromosome 9 open reading frame 16
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CALCR calcitonin receptor
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CCDC71 coiled-coil domain containing 71
CEACAM4 carcinoembryonic antigen-related cell adhesion molecule 4
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLCN7 chloride channel, voltage-sensitive 7
COL7A1 collagen, type VII, alpha 1
CT62 cancer/testis antigen 62
CXCR4 chemokine (C-X-C motif) receptor 4
DGCR8 DGCR8 microprocessor complex subunit
DLL3 delta-like 3 (Drosophila)
DNASE1 deoxyribonuclease I
ECE1 endothelin converting enzyme 1
EFNB3 ephrin-B3
ELAVL3 ELAV like neuron-specific RNA binding protein 3
EMP1 epithelial membrane protein 1
EPB41L4B erythrocyte membrane protein band 4.1 like 4B
ERCC2 excision repair cross-complementation group 2
ESM1 endothelial cell-specific molecule 1
F5 coagulation factor V (proaccelerin, labile factor)
FGF6 fibroblast growth factor 6
FGFR1 fibroblast growth factor receptor 1
FHL1 four and a half LIM domains 1
FRMD1 FERM domain containing 1
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GPR3 G protein-coupled receptor 3
GYG2 glycogenin 2
HHLA1 HERV-H LTR-associating 1
HIPK2 homeodomain interacting protein kinase 2
HKDC1 hexokinase domain containing 1
HSF2BP heat shock transcription factor 2 binding protein
IL17RC interleukin 17 receptor C
IRF4 interferon regulatory factor 4
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KDM4B lysine (K)-specific demethylase 4B
KRT16 keratin 16, type I
KRT17 keratin 17, type I
LRP4 low density lipoprotein receptor-related protein 4
MAN2A2 mannosidase, alpha, class 2A, member 2
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MIER2 mesoderm induction early response 1, family member 2
MMP11 matrix metallopeptidase 11
MRPL41 mitochondrial ribosomal protein L41
MST1 macrophage stimulating 1
MX1 MX dynamin-like GTPase 1
MXRA8 matrix-remodelling associated 8
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
NNAT neuronatin
OGDHL oxoglutarate dehydrogenase-like
PAPPA2 pappalysin 2
PAX8 paired box 8
PDHA2 pyruvate dehydrogenase (lipoamide) alpha 2
PIPOX pipecolic acid oxidase
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PRDX2 peroxiredoxin 2
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTHLH parathyroid hormone-like hormone
PTK2B protein tyrosine kinase 2 beta
PVR poliovirus receptor
RAB6B RAB6B, member RAS oncogene family
RECQL5 RecQ protein-like 5
RFXAP regulatory factor X-associated protein
RGS14 regulator of G-protein signaling 14
RHOBTB2 Rho-related BTB domain containing 2
RPS2 ribosomal protein S2
SBF1 SET binding factor 1
SENP7 SUMO1/sentrin specific peptidase 7
SERHL2 serine hydrolase-like 2
SH3GL3 SH3-domain GRB2-like 3
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
TBXA2R thromboxane A2 receptor
TJAP1 tight junction associated protein 1 (peripheral)
TLDC1 TBC/LysM-associated domain containing 1
TRIM29 tripartite motif containing 29
WIZ widely interspaced zinc finger motifs
WNT16 wingless-type MMTV integration site family, member 16
WNT6 wingless-type MMTV integration site family, member 6
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZFP64 ZFP64 zinc finger protein
ZNF358 zinc finger protein 358
ZNF362 zinc finger protein 362
ZNF646 zinc finger protein 646
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ACTL8 actin-like 8
ADH7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALPK1 alpha-kinase 1
ANKH ANKH inorganic pyrophosphate transport regulator
APLP1 amyloid beta (A4) precursor-like protein 1
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
ATAT1 alpha tubulin acetyltransferase 1
C1QB complement component 1, q subcomponent, B chain
C2ORF27A chromosome 2 open reading frame 27A
C3 complement component 3
C5AR1 complement component 5a receptor 1
C8ORF44 chromosome 8 open reading frame 44
CCNK cyclin K
CD82 CD82 molecule
CLEC4E C-type lectin domain family 4, member E
CLGN calmegin
CNR2 cannabinoid receptor 2 (macrophage)
CTSF cathepsin F
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DEAF1 DEAF1 transcription factor
DENND5B DENN/MADD domain containing 5B
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
EMCN endomucin
FAM110B family with sequence similarity 110, member B
FAM198B family with sequence similarity 198, member B
FKBP1B FK506 binding protein 1B, 12.6 kDa
FSCN3 fascin actin-bundling protein 3, testicular
GADD45G growth arrest and DNA-damage-inducible, gamma
GLRA1 glycine receptor, alpha 1
GLTSCR1 glioma tumor suppressor candidate region gene 1
GPR21 G protein-coupled receptor 21
GPR27 G protein-coupled receptor 27
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HOXC5 homeobox C5
HOXC8 homeobox C8
IDI2-AS1 IDI2 antisense RNA 1
IMPG2 interphotoreceptor matrix proteoglycan 2
IQCG IQ motif containing G
ITM2C integral membrane protein 2C
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KIF13A kinesin family member 13A
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLF7 Kruppel-like factor 7 (ubiquitous)
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LY86 lymphocyte antigen 86
MAGEA5 melanoma antigen family A5
MAPK10 mitogen-activated protein kinase 10
MUL1 mitochondrial E3 ubiquitin protein ligase 1
OCLM oculomedin
OVOL1 ovo-like zinc finger 1
PDE12 phosphodiesterase 12
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PEX26 peroxisomal biogenesis factor 26
PICK1 protein interacting with PRKCA 1
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLTP phospholipid transfer protein
PPP1R9A protein phosphatase 1, regulatory subunit 9A
QPCT glutaminyl-peptide cyclotransferase
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RNF122 ring finger protein 122
RPL10L ribosomal protein L10-like
SAYSD1 SAYSVFN motif domain containing 1
SELL selectin L
SLC16A4 solute carrier family 16, member 4
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SLMO1 slowmo homolog 1 (Drosophila)
SPRR2B small proline-rich protein 2B
STRN striatin, calmodulin binding protein
STX1A syntaxin 1A (brain)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAS2R10 taste receptor, type 2, member 10
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TDRD12 tudor domain containing 12
THRB thyroid hormone receptor, beta
TLR5 toll-like receptor 5
TM4SF4 transmembrane 4 L six family member 4
TMEM120B transmembrane protein 120B
TMPRSS4 transmembrane protease, serine 4
TYRP1 tyrosinase-related protein 1
UPK2 uroplakin 2
WDR62 WD repeat domain 62
WDR76 WD repeat domain 76
WDR78 WD repeat domain 78
XYLT1 xylosyltransferase I
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial
ZBTB22 zinc finger and BTB domain containing 22
ZFP37 ZFP37 zinc finger protein
ZNF10 zinc finger protein 10
ZNF205 zinc finger protein 205
ZNF423 zinc finger protein 423
ZNF552 zinc finger protein 552
ZSWIM1 zinc finger, SWIM-type containing 1