felbinac-4639 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the felbinac-4639 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAP1 ArfGAP with dual PH domains 1
ADRBK1 adrenergic, beta, receptor kinase 1
ALK anaplastic lymphoma receptor tyrosine kinase
AQP3 aquaporin 3 (Gill blood group)
ARHGAP26 Rho GTPase activating protein 26
ARSA arylsulfatase A
ASPHD1 aspartate beta-hydroxylase domain containing 1
BAK1 BCL2-antagonist/killer 1
C1ORF116 chromosome 1 open reading frame 116
C2ORF27A chromosome 2 open reading frame 27A
C7ORF43 chromosome 7 open reading frame 43
CAPN9 calpain 9
CD4 CD4 molecule
CD58 CD58 molecule
CD80 CD80 molecule
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEP290 centrosomal protein 290kDa
COBL cordon-bleu WH2 repeat protein
COL3A1 collagen, type III, alpha 1
CPM carboxypeptidase M
CTIF CBP80/20-dependent translation initiation factor
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit
FCAR Fc fragment of IgA receptor
FDPS farnesyl diphosphate synthase
FRMD8 FERM domain containing 8
FUS FUS RNA binding protein
FZD1 frizzled class receptor 1
GAL3ST1 galactose-3-O-sulfotransferase 1
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GPM6B glycoprotein M6B
GPR1 G protein-coupled receptor 1
GREM1 gremlin 1, DAN family BMP antagonist
GUSBP3 glucuronidase, beta pseudogene 3
HES2 hes family bHLH transcription factor 2
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
HSF1 heat shock transcription factor 1
ICAM2 intercellular adhesion molecule 2
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
ING2 inhibitor of growth family, member 2
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KCNK12 potassium channel, two pore domain subfamily K, member 12
KDM6B lysine (K)-specific demethylase 6B
KIR2DS4 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4
KLHL22 kelch-like family member 22
KRIT1 KRIT1, ankyrin repeat containing
KRT37 keratin 37, type I
LIMCH1 LIM and calponin homology domains 1
LOC390998 ribosomal protein L10 pseudogene
LZTS1 leucine zipper, putative tumor suppressor 1
MST1L macrophage stimulating 1-like
NFX1 nuclear transcription factor, X-box binding 1
NIPAL2 NIPA-like domain containing 2
NMUR1 neuromedin U receptor 1
NPY2R neuropeptide Y receptor Y2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDH11Y protocadherin 11 Y-linked
PCDHB3 protocadherin beta 3
PF4 platelet factor 4
PHF20L1 PHD finger protein 20-like 1
PPP1R37 protein phosphatase 1, regulatory subunit 37
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRF1 perforin 1 (pore forming protein)
PRLH prolactin releasing hormone
PTK7 protein tyrosine kinase 7 (inactive)
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RUNX1 runt-related transcription factor 1
SGK2 serum/glucocorticoid regulated kinase 2
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SPATA2L spermatogenesis associated 2-like
SSBP2 single-stranded DNA binding protein 2
STON1 stonin 1
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SYT5 synaptotagmin V
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAPBP TAP binding protein (tapasin)
TBXA2R thromboxane A2 receptor
TMOD1 tropomodulin 1
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNPO2 transportin 2
TP53I11 tumor protein p53 inducible protein 11
TRIM14 tripartite motif containing 14
TSHR thyroid stimulating hormone receptor
TUBB1 tubulin, beta 1 class VI
UPK1B uroplakin 1B
VGF VGF nerve growth factor inducible
VLDLR very low density lipoprotein receptor
VPS41 vacuolar protein sorting 41 homolog (S. cerevisiae)
ZHX3 zinc fingers and homeoboxes 3
ZNF467 zinc finger protein 467
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ADTRP androgen-dependent TFPI-regulating protein
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ARMCX4 armadillo repeat containing, X-linked 4
ASAP1-IT1 ASAP1 intronic transcript 1
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
BEND5 BEN domain containing 5
C1RL complement component 1, r subcomponent-like
C7ORF69 chromosome 7 open reading frame 69
CASP5 caspase 5, apoptosis-related cysteine peptidase
CASS4 Cas scaffolding protein family member 4
CIR1 corepressor interacting with RBPJ, 1
CISH cytokine inducible SH2-containing protein
CRISP2 cysteine-rich secretory protein 2
CSF1R colony stimulating factor 1 receptor
ELSPBP1 epididymal sperm binding protein 1
FGF6 fibroblast growth factor 6
FGG fibrinogen gamma chain
FILIP1L filamin A interacting protein 1-like
FLJ21369 uncharacterized protein FLJ21369
FLT4 fms-related tyrosine kinase 4
FOXRED2 FAD-dependent oxidoreductase domain containing 2
FRMPD1 FERM and PDZ domain containing 1
GADD45G growth arrest and DNA-damage-inducible, gamma
GPC3 glypican 3
GRAMD1C GRAM domain containing 1C
HAMP hepcidin antimicrobial peptide
HIST1H2AJ histone cluster 1, H2aj
HOXA6 homeobox A6
IFT140 intraflagellar transport 140
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IQCG IQ motif containing G
IRAK4 interleukin-1 receptor-associated kinase 4
KDM7A lysine (K)-specific demethylase 7A
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KRT31 keratin 31, type I
KRT33A keratin 33A, type I
LIG4 ligase IV, DNA, ATP-dependent
LINC00597 long intergenic non-protein coding RNA 597
LOC100127972 uncharacterized LOC100127972
MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K
MAP3K7CL MAP3K7 C-terminal like
MBTPS2 membrane-bound transcription factor peptidase, site 2
METTL16 methyltransferase like 16
MGP matrix Gla protein
MOB3B MOB kinase activator 3B
MORC1 MORC family CW-type zinc finger 1
MRPL41 mitochondrial ribosomal protein L41
MYH7 myosin, heavy chain 7, cardiac muscle, beta
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NXPH4 neurexophilin 4
OLFM4 olfactomedin 4
OLFML2B olfactomedin-like 2B
OR1G1 olfactory receptor, family 1, subfamily G, member 1
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PALM paralemmin
PARM1 prostate androgen-regulated mucin-like protein 1
PLA2G15 phospholipase A2, group XV
PLCD1 phospholipase C, delta 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PRAF2 PRA1 domain family, member 2
PRB3 proline-rich protein BstNI subfamily 3
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PTTG2 pituitary tumor-transforming 2
PWAR5 Prader Willi/Angelman region RNA 5
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RIMBP2 RIMS binding protein 2
RNF126P1 ring finger protein 126 pseudogene 1
RPL10L ribosomal protein L10-like
RRAGB Ras-related GTP binding B
SAMD9 sterile alpha motif domain containing 9
SCAI suppressor of cancer cell invasion
SCG2 secretogranin II
SCN1B sodium channel, voltage gated, type I beta subunit
SDC3 syndecan 3
SETD8 SET domain containing (lysine methyltransferase) 8
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
TBC1D8B TBC1 domain family, member 8B (with GRAM domain)
TCEAL2 transcription elongation factor A (SII)-like 2
TCF15 transcription factor 15 (basic helix-loop-helix)
TGFBI transforming growth factor, beta-induced, 68kDa
TLR2 toll-like receptor 2
TXLNG taxilin gamma
VASH1 vasohibin 1
WDR78 WD repeat domain 78
WFDC2 WAP four-disulfide core domain 2
ZNF208 zinc finger protein 208
ZNF254 zinc finger protein 254
ZNF37BP zinc finger protein 37B, pseudogene
ZNF510 zinc finger protein 510
ZNF768 zinc finger protein 768