felodipine-2433 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the felodipine-2433 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
AFF3 AF4/FMR2 family, member 3
ALG12 ALG12, alpha-1,6-mannosyltransferase
ALOX15B arachidonate 15-lipoxygenase, type B
AMDHD2 amidohydrolase domain containing 2
ANGPTL2 angiopoietin-like 2
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
ATP13A2 ATPase type 13A2
BAGE B melanoma antigen
BCAS1 breast carcinoma amplified sequence 1
BMP7 bone morphogenetic protein 7
BRS3 bombesin-like receptor 3
C7ORF69 chromosome 7 open reading frame 69
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CASP5 caspase 5, apoptosis-related cysteine peptidase
CCDC85C coiled-coil domain containing 85C
CCL13 chemokine (C-C motif) ligand 13
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CFAP69 cilia and flagella associated protein 69
CNGB3 cyclic nucleotide gated channel beta 3
CPN2 carboxypeptidase N, polypeptide 2
CRABP2 cellular retinoic acid binding protein 2
CRYGD crystallin, gamma D
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DCLK2 doublecortin-like kinase 2
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
DSCAM Down syndrome cell adhesion molecule
ERN1 endoplasmic reticulum to nucleus signaling 1
F11R F11 receptor
FCMR Fc fragment of IgM receptor
FGF17 fibroblast growth factor 17
FMO5 flavin containing monooxygenase 5
FOXD2 forkhead box D2
FTH1 ferritin, heavy polypeptide 1
GABRR2 gamma-aminobutyric acid (GABA) A receptor, rho 2
GAS8 growth arrest-specific 8
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GSTA3 glutathione S-transferase alpha 3
HDLBP high density lipoprotein binding protein
HIST1H2BG histone cluster 1, H2bg
HIST1H3B histone cluster 1, H3b
HOXA1 homeobox A1
HOXB3 homeobox B3
HOXB9 homeobox B9
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
IFITM1 interferon induced transmembrane protein 1
IGFBP3 insulin-like growth factor binding protein 3
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIF1A kinesin family member 1A
KRT19P2 keratin 19 pseudogene 2
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LINC00652 long intergenic non-protein coding RNA 652
LPPR1 lipid phosphate phosphatase-related protein type 1
MAPK7 mitogen-activated protein kinase 7
METTL16 methyltransferase like 16
MORN1 MORN repeat containing 1
MTUS1 microtubule associated tumor suppressor 1
MYO15A myosin XVA
MYO6 myosin VI
NOVA2 neuro-oncological ventral antigen 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
NUP214 nucleoporin 214kDa
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OPRM1 opioid receptor, mu 1
PLCH1 phospholipase C, eta 1
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PPP1R26 protein phosphatase 1, regulatory subunit 26
RHO rhodopsin
RIMS2 regulating synaptic membrane exocytosis 2
RRAS2 related RAS viral (r-ras) oncogene homolog 2
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SIGLEC9 sialic acid binding Ig-like lectin 9
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SMR3A submaxillary gland androgen regulated protein 3A
SOCS1 suppressor of cytokine signaling 1
SORBS3 sorbin and SH3 domain containing 3
SPTBN2 spectrin, beta, non-erythrocytic 2
SUGCT succinyl-CoA:glutarate-CoA transferase
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TAT tyrosine aminotransferase
THBS1 thrombospondin 1
TJAP1 tight junction associated protein 1 (peripheral)
TLL1 tolloid-like 1
TTLL7 tubulin tyrosine ligase-like family member 7
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VPREB1 pre-B lymphocyte 1
XDH xanthine dehydrogenase
ZFHX2 zinc finger homeobox 2
ZFYVE9 zinc finger, FYVE domain containing 9

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADGRA3 adhesion G protein-coupled receptor A3
ADRB2 adrenoceptor beta 2, surface
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKRD28 ankyrin repeat domain 28
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
BAHCC1 BAH domain and coiled-coil containing 1
BRMS1 breast cancer metastasis suppressor 1
C1ORF109 chromosome 1 open reading frame 109
CAPRIN2 caprin family member 2
CCNA1 cyclin A1
CD2AP CD2-associated protein
CDADC1 cytidine and dCMP deaminase domain containing 1
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12
COQ6 coenzyme Q6 monooxygenase
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)
CTNNBIP1 catenin, beta interacting protein 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CXCR2 chemokine (C-X-C motif) receptor 2
CXORF56 chromosome X open reading frame 56
DENND4C DENN/MADD domain containing 4C
DHRS11 dehydrogenase/reductase (SDR family) member 11
DHTKD1 dehydrogenase E1 and transketolase domain containing 1
DIXDC1 DIX domain containing 1
EMID1 EMI domain containing 1
ENAH enabled homolog (Drosophila)
ENO2 enolase 2 (gamma, neuronal)
ENO3 enolase 3 (beta, muscle)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ERCC4 excision repair cross-complementation group 4
ETAA1 Ewing tumor-associated antigen 1
FBXL6 F-box and leucine-rich repeat protein 6
FOSB FBJ murine osteosarcoma viral oncogene homolog B
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GIPC1 GIPC PDZ domain containing family, member 1
GLTSCR1 glioma tumor suppressor candidate region gene 1
GPR18 G protein-coupled receptor 18
GUSBP3 glucuronidase, beta pseudogene 3
HCAR3 hydroxycarboxylic acid receptor 3
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
KAT2A K(lysine) acetyltransferase 2A
KLHL28 kelch-like family member 28
LINS lines homolog (Drosophila)
LOC100287590 uncharacterized LOC100287590
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LRP5 low density lipoprotein receptor-related protein 5
LRRC20 leucine rich repeat containing 20
LRRK1 leucine-rich repeat kinase 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
NCS1 neuronal calcium sensor 1
NFE2L3 nuclear factor, erythroid 2-like 3
NPIPB15 nuclear pore complex interacting protein family, member B15
NSD1 nuclear receptor binding SET domain protein 1
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OVGP1 oviductal glycoprotein 1, 120kDa
PARP16 poly (ADP-ribose) polymerase family, member 16
PCSK7 proprotein convertase subtilisin/kexin type 7
PDGFD platelet derived growth factor D
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRMT7 protein arginine methyltransferase 7
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PRSS53 protease, serine, 53
RGS2 regulator of G-protein signaling 2
RHOBTB2 Rho-related BTB domain containing 2
RPA4 replication protein A4, 30kDa
SARS2 seryl-tRNA synthetase 2, mitochondrial
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC39A4 solute carrier family 39 (zinc transporter), member 4
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SPATS2 spermatogenesis associated, serine-rich 2
TBC1D4 TBC1 domain family, member 4
TCTN1 tectonic family member 1
TERT telomerase reverse transcriptase
TET3 tet methylcytosine dioxygenase 3
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM110 transmembrane protein 110
TMEM209 transmembrane protein 209
TNRC6B trinucleotide repeat containing 6B
TRAF1 TNF receptor-associated factor 1
TWISTNB TWIST neighbor
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae)
WDR62 WD repeat domain 62
WDR76 WD repeat domain 76
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
ZNF345 zinc finger protein 345
ZNF76 zinc finger protein 76
ZW10 zw10 kinetochore protein